Spirochetal Diseases
Key concepts • Spirochetal disease includes a historical and clinical gamut of infections causing uveitis, including syphilis, endemic syphilis, Lyme disease, relapsing fever, and leptospirosis. • Ocular findings can occur…
Acute Retinal Necrosis and Progressive Outer Retinal Necrosis
Key concepts • Despite effective antiviral therapies, herpes infection of the eye can lead to severe uveitis with substantial vision loss. • Because acute retinal necrosis (ARN) can often begin…
Other Viral Diseases
Key concepts • Herpes simplex virus (HSV) is a common cause of inflammatory eye disease. • Keratitis and anterior uveitis are frequent manifestations of HSV disease; secondary glaucoma is an…
Examination of the Patient with Uveitis
Key concepts • A thorough ophthalmic examination is critical for both diagnosis and assessing response to therapy. • Use of standardized grading scales for assessing intraocular inflammation can improve patient…
Elements of the Immune System and Concepts of Intraocular Inflammatory Disease Pathogenesis
* The author thanks Drs William Paul and Igal Gery for reviewing this chapter. The helpful parts of the chapter are due to their good and wise counsel. The parts…
Diagnostic Testing
Key concepts • Mistakes in ordering and interpreting diagnostic tests can lead to misdiagnosis and inappropriate therapy. • Diagnostic tests should be ordered to narrow down the differential diagnosis. •…
Evidence-Based Medicine in Uveitis
Key concepts • All published literature does not have equal import. • All medical literature, including this book, must be read critically. • Whenever possible, treatment decisions should be based…
Development of a Differential Diagnosis
Key concepts • Diagnosis of uveitis is often challenging and developing an erudite differential diagnosis is a key to success. • Classification of the uveitis is the first step and…
Medical History in the Patient with Uveitis
Key concepts • A detailed medical history is the key to diagnosis in the majority of cases of uveitis. • A uveitis medical history questionnaire provides a core of standardized…
Corneal Infections, Inflammations, and Surface Disorders
Corneal Infections, Inflammations, and Surface Disorders BACTERIAL KERATITIS Bacterial keratitis is a serious, potentially sight-threatening corneal infection that typically develops in patients with a compromised corneal surface. Predisposing Factors •…
