Purpose To describe the natural history of Leber congenital amaurosis (LCA) associated with GUCY2D variants ( GUCY2D -LCA) in a cohort of children and adults, in preparation for trials of…
Purpose To report the outcomes of medical and surgical management for congenital aniridia-associated keratopathy (AAK) over a long-term follow-up period. Design Retrospective, comparative case series. Methods Medical records of patients…
Purpose To evaluate the performance of 3-dimensional (3D) endothelium/Descemet membrane complex thickness (En/DMT) maps vs total corneal thickness (TCT) maps in the diagnosis of active corneal graft rejection. Design Cross-sectional…
Purpose To provide a state-level prediction of the future burden of visual impairment and its causes in adults in the state of Georgia through 2050, accounting for age and race…
Purpose To determine the association of age-related macular degeneration (AMD) with Alzheimer disease (AD) and Parkinson disease (PD). Design Retrospective cohort study. Methods The study population consisted of 308,340 participants…
Purpose To investigate whether progressive macular ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thinning predict development of visual field (VF) defects in glaucoma suspects. Design…
Purpose To assess short- and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma. Design Prospective cohort. Methods Ordinary least squares linear regression…
Purpose To evaluate long-term outcomes of surgical treatment for abnormal head positioning (AHP) associated with infantile nystagmus syndrome (INS). Design Retrospective observational case series. Methods Review of 150 patients who…
Ophthalmology is rooted in a rich history of imaging and equipment-assisted examination. Ancient dissections of the human eye by polymaths such as Aristotle and Rufus of Ephesus disclosed a cascading…
Purpose To report outcomes and complications of trabeculotomy ab interno using the Trab360 device (Trab360; Sight Sciences, Menlo Park, California, USA) in eyes with childhood glaucomas. Design Multicenter retrospective interventional…
