42.1 Features Choroideremia is X-linked chorioretinal dystrophy characterized by progressive degeneration and atrophy of the retinal pigment epithelium (RPE), choriocapillaris, and retina. First described by Mauthnuer in 1872, its prevalence is…
Features Intermediate uveitis is the general terminology for inflammation localized predominantly in the vitreous, ciliary body, and peripheral retina that may or may not be associated with an infectious agent…
28.1 Features Polypoidal choroidal vasculopathy (PCV) is known to be more common in people of Asian and African ancestry. Clinically, PCV is characterized by polypoidal aneurysmal dilations of network vessels originating…
Features Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an idiopathic bilateral inflammatory condition most often affecting young individuals aged 20 to 40 years with equal sex predilection. The disease…
Features Multiple evanescent white dot syndrome (MEWDS) is unilateral, multifocal retinitis that affects young, myopic women aged 12 to 57 years, with a mean age of 27 years. Females are…
36.1 Features Retinitis pigmentosa (RP) is a group of genetically and phenotypically heterogeneous conditions affecting approximately 1 in 4,000 individuals. RP can be inherited in an autosomal dominant (15–25%), autosomal recessive…
32.1 Features Autosomal dominant (AD) cases have early age of onset and diagnosis occurs in early childhood to teenage years. In a minority of patients, a choroidal neovascular membrane (CNVM) can…
Features Ocriplasmin is a recombinant truncated form of plasmin approved by the FDA in 2012 for the treatment of symptomatic vitreomacular adhesion. The enzyme has nonspecific proteolytic activity against multiple…
Features Familial exudative vitreoretinopathy (FEVR) is an inherited vitreoretinal disease characterized by abnormal retinal vascular development. FEVR is a lifelong disease that often shows progression with periods of quiescence and…
52.1 Features Toxoplasma retinochoroiditis is the most common cause of infectious posterior uveitis in immunocompetent individuals and is a result of congenital or acquired infection with the ubiquitous intracellular protozoan parasite…
