58 Early Intervention and Rehabilitation
FIGURE 58.1A: Opening the eyes did not change the image, so the baby kept the eyes shut. B: After the operation of the right eye, she received near correction glasses…
6 Choroidal Vascular Development
FIGURE 6.1 Cross-sections of 6.5 WG fetal choroid demonstrate hemovasculogenesis (A–F). Erythroblasts (bright pink cytoplasm) in the CC layer can form solid cord-like structures (double arrow) without a lumen (A). Erythroblasts…
52 Coats Disease
From Gomez Morales A. Coats’ disease. Natural history and results of treatment. Am J Ophthalmol 1965;60:855–864; Shields JA, Shields CL, Honavar SG, et al. Classification and management of Coats’ disease:…
24 Gene Therapy and Pharmacology
Listed are the diseases, the genetic defects, and the gene therapy strategies under consideration. ABCA4, ATP-binding cassette transporter cassette A member 4 gene; AR, autosomal recessive; NA, not applicable; AD,…
43 Oxidative Stress and Signaling Pathways Involved in Developmental and Aberrant Angiogenesis Relating to Retinopathy of Prematurity
FIGURE 43.1 Factors contribute to the development of ROP. Low serum insulin-like growth factor-1 (IGF-1) and its binding protein 3 IGFBP3 derived from preterm birth lead to impaired retinal vascular development….
1 Embryology of the Retina and Developmental Disorders
RPE, retinal pigment epithelium. TABLE 1.2 Time line of retinal development: organogenesis RPE, retinal pigment epithelium. TABLE 1.3 Time line of retinal development: differentiation IRBP, interstitial retinol-binding protein. FIGURE 1.1 Four-week-old…
