GUCY2D-Associated Leber Congenital Amaurosis: A Retrospective Natural History Study in Preparation for Trials of Novel Therapies

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on GUCY2D-Associated Leber Congenital Amaurosis: A Retrospective Natural History Study in Preparation for Trials of Novel Therapies

Purpose To describe the natural history of Leber congenital amaurosis (LCA) associated with GUCY2D variants ( GUCY2D -LCA) in a cohort of children and adults, in preparation for trials of…

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Management of Congenital Aniridia-Associated Keratopathy: Long-Term Outcomes from a Tertiary Referral Center

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Management of Congenital Aniridia-Associated Keratopathy: Long-Term Outcomes from a Tertiary Referral Center

Purpose To report the outcomes of medical and surgical management for congenital aniridia-associated keratopathy (AAK) over a long-term follow-up period. Design Retrospective, comparative case series. Methods Medical records of patients…

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Diagnostic Performance of Three-Dimensional Endothelium/Descemet Membrane Complex Thickness Maps in Active Corneal Graft Rejection

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Diagnostic Performance of Three-Dimensional Endothelium/Descemet Membrane Complex Thickness Maps in Active Corneal Graft Rejection

Purpose To evaluate the performance of 3-dimensional (3D) endothelium/Descemet membrane complex thickness (En/DMT) maps vs total corneal thickness (TCT) maps in the diagnosis of active corneal graft rejection. Design Cross-sectional…

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Association of Age-Related Macular Degeneration on Alzheimer or Parkinson Disease: A Retrospective Cohort Study

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Association of Age-Related Macular Degeneration on Alzheimer or Parkinson Disease: A Retrospective Cohort Study

Purpose To determine the association of age-related macular degeneration (AMD) with Alzheimer disease (AD) and Parkinson disease (PD). Design Retrospective cohort study. Methods The study population consisted of 308,340 participants…

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Ganglion Cell-Inner Plexiform Layer and Retinal Nerve Fiber Layer Changes in Glaucoma Suspects Enable Prediction of Glaucoma Development

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Ganglion Cell-Inner Plexiform Layer and Retinal Nerve Fiber Layer Changes in Glaucoma Suspects Enable Prediction of Glaucoma Development

Purpose To investigate whether progressive macular ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thinning predict development of visual field (VF) defects in glaucoma suspects. Design…

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Comparison of Short- And Long-Term Variability in Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Comparison of Short- And Long-Term Variability in Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma

Purpose To assess short- and long-term variability on standard automated perimetry (SAP) and spectral domain optical coherence tomography (SD-OCT) in glaucoma. Design Prospective cohort. Methods Ordinary least squares linear regression…

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Long-term Outcomes Following Surgery for Infantile Nystagmus Syndrome With Abnormal Head Positioning

Mar 14, 2020 by in OPHTHALMOLOGY Comments Off on Long-term Outcomes Following Surgery for Infantile Nystagmus Syndrome With Abnormal Head Positioning

Purpose To evaluate long-term outcomes of surgical treatment for abnormal head positioning (AHP) associated with infantile nystagmus syndrome (INS). Design Retrospective observational case series. Methods Review of 150 patients who…

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