Purpose To describe, apply, and test a new ocular grading system for assessing keratoconjunctivitis sicca (KCS) using lissamine green and fluorescein. Design Prospective, observational, multicenter cohort study. Methods The National…
Purpose To evaluate complications and clinical outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) with intraocular lens (IOL) exchange compared with DSAEK alone. Design Retrospective, interventional case series. Methods DSAEK…
Purpose To summarize emerging concepts regarding the onset and progression, traction effects, and complications of the early stages of age-related posterior vitreous detachment (PVD). Design Interpretive essay. Methods Review and…
Purpose To describe a patient with 2 ipsilateral supernumerary caruncles and to determine if they are predictive of associated abnormalities. Design Retrospective and interventional clinicopathologic study with a critical review…
Purpose To determine whether implantation of an aspherical intraocular lens (IOL) results in reduced ocular aberrations and improved contrast sensitivity after cataract surgery without critical reduction of depth of focus….
Facing an enormous influx of information from medical research, clinicians need to differentiate robust study findings from spurious ones and to decide which results they can use with high confidence…
In the 1950s and ’60s, a doctoral student in biostatistics could be reasonably expected to acquire a fairly sophisticated knowledge of the whole field before completing the doctoral dissertation. This…
Although von Graefe described some of the clinical aspects of “relapsing idiopathic detachment of the macula” as early as 1866, it was more than 100 years later that Maumenee, using…
Most medical journals do not have a mechanism for producing well-written evidence-based medicine on a measured monthly basis. Some published articles are poorly written and some have few usable clinical…
Purpose To evaluate the intraocular pressure (IOP)-lowering efficacy and safety of ophthalmic formulations of bimatoprost 0.01% and 0.0125% compared with bimatoprost 0.03%. Design Prospective, randomized, double-masked, multicenter clinical trial. Methods…
