Artificial Cochlear Epithelium
Fig. 17.1 Travelling wave theory and our hypothesis [4] The cochlear implant is a hearing device that restores hearing in deafened patients, of which development is worthy for Lascar prize….
Anatomy of the Inner Ear
Fig. 1.1 Membranous labyrinth of vertebrates. Membranous labyrinths of a rat (a), a bird (b), and a fish (c) were shown. (Modified from “The Vertebrate body” by Romer et al….
Regenerative Medicine for the Inner Ear: Summary
Subjects: unilateral acute profound hearing loss; systemic steroid treatment application is ineffective within 1 month after deafness onset Single application (5 mg) of IGF-1 containing hydrogel on the RWM Observation period: 2 months…
Cochlear Development
Fig. 12.1 Graphical abstract of Chap. 12. (Modified from [68]) 12.1.1 Factors Regulating Cochlear Duct Extension Multiple extrinsic factors regulate proper outgrowth and extension of the cochlear duct. One clear…
Vestibular Development
Fig. 13.1 Subcellular planar polarity. (Modified from Deans [2]) Fig. 13.2 Planar cell polarity (PCP). (Modified from Deans [2]) Fig. 13.3 Tissue polarity. (Modified from Deans [2]) 13.4.1 Subcellular Planar…
Cell Therapy for Regeneration of Spinal Ganglion Neurons
Fig. 28.1 (a) During normal development, sensory neuroblasts delaminate from the otocyst epithelium and migrate through the periotic mesenchyme (POM). During this phase there is a period of proliferation called…
Clinical Background
Fig. 25.1 Diverse causes of the clinically diagnosed “retrocochlear” type of hearing loss. The precise pathology of each case is often difficult to determine clinically. Note that “synaptopathy” refers to…
Hair Cell Regeneration in the Avian
Fig. 19.1 Structure of inner ear sensory epitheria (modified from [1]). (a) Mammalian organ of Corti. (b) Avian basilar papilla. (c) Avian and mammalian vestibular epitheria Another typical point of…
Transdifferentiation
Fig. 21.1 Schematic illustration of normal development, de-differentiation, and transdifferentiation. The top of the hill represents an immature status of the cell, and the bottom represents a differentiated status. (a)…
Auditory Brainstem Implant
Fig. 18.1 (a) Cross section of pontomedullary junction at level of lateral recess of the fourth ventricle (4th Vent.). DCN (Dorsal Coch. Nucl.) and VCN (Ventral Coch. Nucl.) are located…
