General Principles of Medical Therapy
• History of trauma/injury with vegetative matter • History of contact lens use • Past history of viral keratitis Slit lamp evaluation suggestive of poor ocular surface, presence of corneal…
Medical Therapy Algorithms
Points Suggestive of Infectious Aetiology • History of trauma/injury with vegetative matter • History of Contact lens use • Past history of viral keratitis • Slit lamp evaluation suggestive of…
Investigative Modalities
Fig. 4.1 AS-OCT shows area of inflammation with edema and gross separation of the collagen fibers Necrotizing Anterior Scleritis This condition is characterized by the destruction of the collagen fibers and…
General Principles of Surgery
Causes of PUK 1. Inflammatory disorders – Systemic vasculitides • Rheumatoid arthritis • Wegener’s granulomatosis • Polyarteritis nodosa • Relapsing polychondritis – Ocular conditions • Mooren’s Ulcer • Marginal keratitis…
Clinical Syndromes, Classifications, and Differential Diagnosis
Systemic diseases 1. Rheumatoid arthritis 2. Wegener’s granulomatosis 3. Systemic lupus erythematosus 4. Polyarteritis nodosa 5. Relapsing polychondritis 6. Progressive systemic sclerosis 7. Giant cell arteritis 8. Churg-Strauss syndrome 9….
C-shaped Lamellar Corneal Patch Grafts “Match and Patch” Technique
Fig. 11.1 Photograph demonstrating a case with severe extensive (Almost 270°) peripheral corneal thinning before and after surgical intervention using the “match and patch” technique Concept of “Match and Patch” The…
Anatomical Considerations
Fig. 1.1 Anatomy of the limbus The limbus is composed of only two layers namely the epithelium and the stroma, because the Bowman’s membrane stops abruptly and Descemet’s membrane merges into…
Noninfectious Causes
Fig. 9.1 a, b Peripheral ulcerative keratitis On examination, early PUK manifests as peripheral corneal opacities composed of stromal cellular infiltrates in the perilimbal cornea. Progressive disease is exhibited by breakdown…
Clinical Evaluation
Clinical features Systemic disease Skin and hair Rash/ulcers All vascular syndromes, SLE Sunburn easily SLE, PSS Depigmentation SLE Loss of hair PSS, SLE, GCA Painfully cold fingers PSS Puffy hands…
Practical Guide to Immunomodulatory Agents
• Minimal fetal or maternal risk Hydroxychloroquine Sulfasalazine • Selective use allowed during pregnancy NSAIDs and aspirin Glucocorticoids Azathioprine and 6-MP TNF inhibitors Intravenous immune globulin Cyclosporine Tacrolimus • Contraindicated…
