Key points • The inner ear has several structural and functional characteristics that make it an appealing target for novel gene therapy, RNA-based therapy, and stem cell therapy for treatment…
Auditory brainstem implants (ABIs) provide auditory perception in patients with profound hearing loss who are not candidates for the cochlear implant (CI) because of anatomic constraints or failed CI surgery….
Key points • Early identification and intervention by qualified professionals is critical to successful outcomes for children with hearing loss. • Families of children with hearing loss should receive thorough…
Key points • The initiation of newborn hearing screening and the resultant opportunity for children with hearing loss to begin early intervention in the first months of life have dramatically…
Key points • Autosomal-recessive (AR) nonsyndromic hearing loss is usually prelingual and frequently results in severe hearing loss, although milder and progressive hearing loss forms also exist. GJB2 and SLC26A4…
Key points • Syndromic hearing loss (SHL) is a form of hearing loss (HL) accompanied by additional clinical features in the visual, nervous system, endocrine, and other systems. The most…
Key points • Effect, directly or indirectly, is on neural processing of auditory stimuli. ○ Physiologic measures are needed to accurately characterize patients with auditory neuropathy spectrum disorder (ANSD). ○…
Key points • Lack of binaural input results in difficulties with sound localization and understanding speech in noisy backgrounds. • Children with unilateral hearing loss (UHL) are at risk for…
Key points • Early diagnosis of hearing loss with a combination of electrophysiological and behavioral test measures is critical in initiating treatment during a period of maximal neural plasticity. •…
Key points • Management of children with hearing loss requires collaborative, interprofessional teams focused on patient-centered goals and shared problem solving. • Referrals to otolaryngologists, audiologists, and speech-language pathologists with…
