Clinical Diagnostic Gene Expression Thyroid Testing

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Clinical Diagnostic Gene Expression Thyroid Testing

Thyroid fine-needle aspiration biopsies are cytologically indeterminate in 15% to 30% of cases. When cytologically indeterminate thyroid nodules undergo diagnostic surgery, approximately three-quarters prove to be histologically benign. A negative…

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Decision Making for Diagnosis and Management

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Decision Making for Diagnosis and Management

Cases are presented in light of the current diagnostic and therapeutic trends in management of thyroid nodules and well-differentiated cancers. Demographic, historical, and population-based risk factors are used to risk…

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Clinical Application of Molecular Testing of Fine-needle Aspiration Specimens in Thyroid Nodules

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Clinical Application of Molecular Testing of Fine-needle Aspiration Specimens in Thyroid Nodules

Key points • Distinct genetic alterations involving the mitogen-activated protein kinase and phosphatidylinositol 3 kinase pathways characterize thyroid cancer subtypes, and can be detected in preoperative fine-needle aspiration biopsy specimens….

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Management of the Neck in Thyroid Cancer

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Management of the Neck in Thyroid Cancer

The management of regional lymph nodes in thyroid carcinoma is guided by preoperative evaluation, histologic subtype, and often a consideration of data for potential benefit and morbidity of a neck…

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Contemporary Surgical Techniques

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Contemporary Surgical Techniques

Recent technologic advances have engendered alternative and innovative approaches to thyroid surgery aimed at reducing cosmetic sequelae. Minimally invasive techniques via small anterior cervical incisions hidden in natural skin creases…

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Surgical Diagnosis

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Surgical Diagnosis

This article outlines features of the biology of well differentiated thyroid cancer, and how these impact on systems of risk prediction. It covers salient points that the surgeon should consider…

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Thyroid Cytology

Apr 1, 2017 by in OTOLARYNGOLOGY Comments Off on Thyroid Cytology

This article covers, in a comprehensive way, thyroid cytopathology. The Bethesda System for Reporting Thyroid Cytology is reviewed, with emphasis on the atypical and indeterminate diagnostic categories. Immunohistochemistry stains and…

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