One-Year Tumor Volume Regression Predicts Survival After I-125 Plaque Brachytherapy for Posterior Uveal Melanoma

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on One-Year Tumor Volume Regression Predicts Survival After I-125 Plaque Brachytherapy for Posterior Uveal Melanoma
Objective To evaluate the prognostic significance of one-year tumor volume regression (TVR) following low-dose-rate iodine-125 episcleral plaque brachytherapy (EPBT) in patients with uveal melanoma. Design Retrospective single-center clinical cohort study….
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Efficacy and Safety of Gene Therapy for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Efficacy and Safety of Gene Therapy for Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
Topic This systematic review and meta-analysis evaluated whether gene therapy provides safe and clinically meaningful efficacy for patients with neovascular age-related macular degeneration (nAMD). The clinical question addressed outcomes in…
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Ocular Symptoms Lead to Shortest Diagnostic Delay in Biopsy-Proven Giant Cell Arteritis: A Nationwide Veterans Health Study

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Ocular Symptoms Lead to Shortest Diagnostic Delay in Biopsy-Proven Giant Cell Arteritis: A Nationwide Veterans Health Study
Purpose To evaluate diagnostic delays in biopsy-proven giant cell arteritis (GCA) within the Veterans Health Administration (VHA), with a focus on the impact of presenting symptoms and provider specialty on…
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Comment on: Assessing the Fragility of Statistically Significant Outcomes in Randomised Controlled Trials of Minimally Invasive Glaucoma Surgery (MIGS)

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Comment on: Assessing the Fragility of Statistically Significant Outcomes in Randomised Controlled Trials of Minimally Invasive Glaucoma Surgery (MIGS)
W e read with great interest the article by Ansari et al on the fragility in studies of minimally invasive glaucoma surgery (MIGS), and we would like to comment on…
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Tubercular Retinitis: Clinical Spectrum and Multimodal Imaging Features of an Insufficiently Characterized Entity

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Tubercular Retinitis: Clinical Spectrum and Multimodal Imaging Features of an Insufficiently Characterized Entity
Purpose Ocular tuberculosis (OTB) affecting the posterior segment commonly presents with choroiditis lesions. However, tubercular retinitis (TBR) is a rare and poorly characterized phenotype. This study aims to define the…
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Imaging Biomarkers for Early Differentiation of Candida and Aspergillus Endogenous Fungal Endophthalmitis: Multicenter Optical Coherence Tomography-Based Analysis

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Imaging Biomarkers for Early Differentiation of Candida and Aspergillus Endogenous Fungal Endophthalmitis: Multicenter Optical Coherence Tomography-Based Analysis
Purpose Endogenous fungal endophthalmitis (EFE) is a rare, sight-threatening intraocular infection with heterogeneous clinical presentations. Candida and Aspergillus species are the most common etiologic agents and may manifest with retinochoroiditis…
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Genotype–Phenotype Correlations in RPGRIP1 -Associated Retinal Dystrophy in a Nationwide Japanese Cohort

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Genotype–Phenotype Correlations in RPGRIP1 -Associated Retinal Dystrophy in a Nationwide Japanese Cohort
Purpose To investigate genotype–phenotype correlations in a nationwide Japanese cohort of patients with RPGRIP1 -associated retinal dystrophy. Design Retrospective, multicenter cohort study. Methods Japanese patients with biallelic pathogenic RPGRIP1 variants…
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Altitude-Specific IOP Risks After Vitrectomy With Gas Tamponade: Modeling and Travel Guidance Based on Calculated Elevation Profiles

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Altitude-Specific IOP Risks After Vitrectomy With Gas Tamponade: Modeling and Travel Guidance Based on Calculated Elevation Profiles
Purpose To develop a globally applicable, theoretical mathematical construct for predicting altitude-related intraocular pressure (IOP) elevation following pars plana vitrectomy (PPV) with intraocular gas tamponade, enabling personalized travel risk assessment…
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Auto Machine Learning for Diabetic Retinopathy Screening: A Head-to-Head Multiplatform Comparison Against Human Graders and IDx-DR

Sep 20, 2026 by in OPHTHALMOLOGY Comments Off on Auto Machine Learning for Diabetic Retinopathy Screening: A Head-to-Head Multiplatform Comparison Against Human Graders and IDx-DR
Highlights • We performed a head-to-head benchmark of AutoML platforms for DR screening. • Amazon SageMaker Canvas and AutoGluon achieved the highest AUCs for RDR and STDR. • Model performance…
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