Systemic Pain Conditions and Dry Eye Disease
The Link Between Systemic Pain Conditions and Dry Eye Introduction Chronic pain is a pain that persists or recurs for longer than 3 months. With an estimated 20% prevalence in the…
Glaucoma and Dry Eye Syndrome: Double Trouble
Acknowledgments I would like to thank Sunita Radhakrishnan, Robert Honkanen, and Sarah Weissbart for their valuable input on this topic. Thank you to Samuel Gurevich for helping in editing and…
Treatment of Dry Eye Disease in Europe
European Dry Eye Society The European Dry Eye Society (EuDES) was founded in 2020. Its goal is to support European researchers and clinicians to expand our knowledge in the area…
Sjögren’s Syndrome Dry Eye Disease
Acknowledgment We wish to acknowledge Chuan Yu Wu for his asssistance in creating Fig. 6.1 . Introduction The term keratoconjunctivitis sicca , introduced by the Swedish ophthalmologist Henrik Sjögren, refers to…
Pathophysiology of Dry Eye Disease Using Animal Models
Introduction Dry eye disease (DED) is a multifactorial condition of the ocular surface, characterized by chronic inflammatory damages of the cornea and conjunctiva, along with the involvement of Meibomian and…
Pathophysiology of Dry Eye Disease Using Human Models
Introduction Dry eye disease (DED) is an umbrella term that represents a wide spectrum of disorders with different clinical presentations and variable risk factors. In 2017, in light of studies…
Clinical Assessment of Dry Eye Disease: Nerve Health
Introduction Dry eye disease (DED) is a multifactorial disease for which the exact pathophysiological mechanism remains unknown. Nevertheless, a combination of a compromised tear film, ocular surface inflammation, and neurosensory…
Questionnaire Design and Use to Assess Dry Eye Disease
The accepted TFOS DEWS II definition (2017) of dry eye includes symptoms as a required element of a diagnosis of dry eye disease and this was also the case with…
Clinical Assessments of Dry Eye Disease: Tear Film and Ocular Surface Health
Introduction Over the last 25 years, our collective knowledge of dry eye disease (DED) has grown exponentially, yet many of the most commonly used clinical diagnostic tests have remained largely…
Robot-based otological surgery
Introduction Robot-based surgery first emerged in the mid-eighties, with orthopedic and neurosurgical applications [ ]. The RoboDoc® system, reported by Taylor et al. [ ], was designed to assist the…
