Histopathology of Age-Related Macular Degeneration
Figure 5.1 Histopathological changes in the two main forms of AMD. This diagram is showing the structural and functional changes of a normal RPE cell when developing dry or wet…
Macugen for Age-Related Macular Degeneration
Figure 16.1 Pegaptanib structure and target binding. A. Sequence and predicted secondary structure of pegaptanib. 2′-O-methylated purines are shown in red, 2′-fluorine-modified pyrimidines are shown in blue, and unmodified ribonucleotides…
Introduction to Gene Therapy and Related Techniques for Retinal Disorders and Age-Related Macular Degeneration
At present, there are two general approaches by which therapeutic AAV-mediated gene transfer might be useful in the context of ocular disease. First, AAV-mediated gene therapy has the potential to…
