Unexplained Cough in the Adult
Unexplained cough is a diagnosis of exclusion that should not be made until a thorough validated diagnostic evaluation is performed, specific and appropriate validated treatments have been tried and failed,…
Future Directions in Treating Cough
Cough is a common and troublesome symptom that can be difficult to treat. New therapeutic options that are safe and more effective than those currently available are needed. In this…
Assessing Efficacy of Therapy for Cough
An antitussive agent should reduce the amount of coughing experienced by the patient sufficiently for the patient to appreciate an improvement in cough severity and regard the improvement as sufficient…
The Spectrum of Nonasthmatic Inflammatory Airway Diseases in Adults
When the airways are overwhelmed by noxious particles, gases, or microorganisms, inflammatory and immune responses occur that may cause permanent structural changes. One consequence may be an overproduction of mucus…
Cough in the Pediatric Population
Children with cough, in particular chronic cough, are sometimes referred to otolaryngologists for assessment, diagnosis, and management. Although the likely diagnoses encountered by otolaryngologists are rhinosinusitis, foreign body aspiration, and…
Pharmacologic Management of Cough
This review is an update of recent advances in our understanding of cough suppressants and impairment of cough. Low-dose oral morphine has recently been shown to significantly suppress chronic cough,…
Rhinogenic Laryngitis, Cough, and the Unified Airway
Over the past 10 years, there has been increasing recognition of the interaction between the upper and lower airways in patients with a variety of infectious and inflammatory illnesses, including…
Cough Due to Asthma, Cough-Variant Asthma and Non-Asthmatic Eosinophilic Bronchitis
Among the most common causes of chronic cough are asthma (25%) and nonasthmatic eosinophilic bronchitis (10%). In asthma, cough may present as an isolated symptom, in which case it is…
Reflux and Cough
Reflux is a significant contributor to cough in otolaryngology practice; cough is just one marker of its many negative effects on the upper aerodigestive tract. Reflux causes cough both by…
Occupational, Environmental, and Irritant-Induced Cough
Occupational and environmental irritants play a role in the pathogenesis of chronic cough. An irritant is a non-corrosive chemical, which causes a reversible inflammatory change on living tissue by chemical…
