Clinical Trials in Wet Age-Related Macular Degeneration Stephen A. McNutt MD Peter K. Kaiser MD Age-related macular degeneration (AMD) remains the leading cause of blindness in the developed world and…
Proliferative Diabetic Retinopathy: Clinical Trials Dean Eliott MD I. DIABETIC RETINOPATHY STUDY Introduction Eyes that develop proliferative diabetic retinopathy (PDR) have at least a 50% probability of becoming blind within…
Clinical Trials in Nonneovascular Age-Related Macular Degeneration Benjamin Nicholson MD Emily Y. Chew MD Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world.1,2 There are…
Diabetic Macular Edema: Clinical Trials Yoshihiro Yonekawa MD Dean Eliott MD I. DIABETIC MACULAR EDEMA Early Treatment Diabetic Retinopathy Study Introduction In the 1960s, diabetic retinopathy was a growing public…
Diabetic Retinopathy: Prevention and Screening Dean Eliott MD Yoshihiro Yonekawa MD I. DIABETES CONTROL AND COMPLICATIONS TRIAL Introduction Long-term microvascular and neurologic complications cause considerable morbidity and mortality in patients…
Glaucoma: Clinical Trials in Glaucoma Therapy Daniel Warder MD Robert J. Campbell MD, MSc, FRCSC Glaucoma, with its characteristic optic nerve pathology and associated visual field (VF) defects, results from…
Anterior Segment: Cornea and External Diseases Ayad A. Farjo MD Qais A. Farjo MD Herpes Simplex Virus Eye Disease of the Anterior Segment Introduction and Epidemiology Herpes simplex virus type…
Refractive Surgery Patrick T. Yang MD Louis E. Probst MD Clara C. Chan MD, FRCSC, FACS Refractive surgery has at least two unique characteristics when compared with the other subspecialties…
Biostatistics Simon Hollands MD, MSc (Epid) Sanjay Sharma MD, MS (Epid), FRCSC, MBA Hussein Hollands MD, FRCSC, MSc (Epid) Introduction In Chapter 1 various study designs were discussed in order…
Health Economics Hussein Hollands MD, FRCSC, MSc (Epid) Sanjay Sharma MD, MS (Epid), FRCSC, MBA Introduction Economic evaluation in medicine has the potential to greatly influence policy decisions in both…
