Introduction Meibomian gland dysfunction (MGD) is among the most commonly encountered chronic ocular conditions in clinical practice, and is acknowledged to be a leading contributor of evaporative dry eye disease….
Introduction Graft-versus-host disease (GVHD) is a potentially life-threatening multiorgan systemic disease affecting patients treated with hematopoietic stem cell transplantation (SCT). GVHD is characterized by immune dysregulation and tissue inflammation with…
Introduction Sensory nerves normally convey signals of pain to the brain. Yet, the overall experience and behavioral manifestations of pain are determined by mechanisms within the peripheral and central nervous…
Introduction Neuropathic ocular pain (NOP) in dry eye disease (DED) has hitherto remained an underdiagnosed and challenging condition to treat. The pathogenesis of NOP includes injury to the corneal nerves,…
The treatment of meibomian gland dysfunction (MGD) first requires both proper diagnosis of the condition and identification of contributory ocular surfaces disorders that may confuse proper attribution of both patient…
The Link Between Systemic Pain Conditions and Dry Eye Introduction Chronic pain is a pain that persists or recurs for longer than 3 months. With an estimated 20% prevalence in the…
Acknowledgments I would like to thank Sunita Radhakrishnan, Robert Honkanen, and Sarah Weissbart for their valuable input on this topic. Thank you to Samuel Gurevich for helping in editing and…
European Dry Eye Society The European Dry Eye Society (EuDES) was founded in 2020. Its goal is to support European researchers and clinicians to expand our knowledge in the area…
Acknowledgment We wish to acknowledge Chuan Yu Wu for his asssistance in creating Fig. 6.1 . Introduction The term keratoconjunctivitis sicca , introduced by the Swedish ophthalmologist Henrik Sjögren, refers to…
Introduction Dry eye disease (DED) is a multifactorial condition of the ocular surface, characterized by chronic inflammatory damages of the cornea and conjunctiva, along with the involvement of Meibomian and…
