Chen and associates reported on the efficacy and safety of apraclonidine 0.5% in diagnosing Horner syndrome in children under high and low illumination. They describe a prospective study comparing 10…
I write concerning the article by Lim and associates about the relation of retinal vascular caliber with optic disc and macular structure. They found that larger cup-to-disc ratios and thinner…
Objective To identify a disease locus for autosomal recessive retinitis pigmentosa in a consanguineous Pakistani family. Design Prospective linkage study. Methods Blood samples were collected and genomic DNA was extracted….
Subramanian and associates report that their randomized controlled trial originally was powered on the basis of an overall sample size of 135 patients (90 in the bevacizumab group and 45…
Purpose To evaluate the influence of the extent of myopia on the progression rate of normal-tension glaucoma (NTG). Design Retrospective, observational case series. Methods One hundred forty-three eyes of 143…
Purpose To validate a third-generation performance-based measure of visual function titled “Assessment of Disability Related to Vision” (ADREV) in a study population of patients with diabetic retinopathy. Design Prospective, cross-sectional…
Purpose Stimulation of nicotinic acetylcholine (nACh) receptors on vascular endothelial cells promotes angiogenesis and vascular permeability in animal models. The safety and bioactivity of topical mecamylamine, an antagonist of nACh…
Purpose To assess whether the genetic polymorphisms of estrogen receptor beta ( ESR2 ) are associated with primary open-angle glaucoma (POAG). Design Case-control study. Methods Four hundred and twenty-five Japanese…
