12.
Kilpivaara O, Aaltonen LA. Diagnostic cancer genome sequencing and the contribution of germline variants. Science. 2013;339(6127):1559–62.PubMed
13.
Purvis JE, Lahav G. Encoding and decoding cellular information through signaling dynamics. Cell. 2013;152(5):945–56.PubMedCentralPubMed
14.
Wade M, Li YC, Wahl GM. MDM2, MDMX and p53 in oncogenesis and cancer therapy. Nat Rev Cancer. 2013;13(2):83–96.PubMedCentralPubMed
16.
Sperka T, Wang J, Rudolph KL. DNA damage checkpoints in stem cells, ageing and cancer. Nat Rev Mol Cell Biol. 2012;13(9):579–90.PubMed
17.
Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer. 2012;12(9):613–26.PubMed
18.
Freed-Pastor WA, Prives C. Mutant p53: one name, many proteins. Genes Dev. 2012;26(12):1268–86.PubMedCentralPubMed
19.
Sahin E, DePinho RA. Axis of ageing: telomeres, p53 and mitochondria. Nat Rev Mol Cell Biol. 2012;13(6):397–404.PubMedCentralPubMed
20.
Shen Y, White E. P53-dependent apoptosis pathways. Adv Cancer Res. 2005;82:55–84.
21.
Vousden KH, Lu X. Live or let die: the cell’s response to p53. Nat Rev Cancer. 2002;2(8):594–604.PubMed
22.
Oren M. Decision making by p53: life, death and cancer. Cell Death Differ. 2003;10(4):431–42.PubMed
23.
Manfredi JJ. p53 and apoptosis: it’s not just in the nucleus anymore. Mol Cell. 2003;11(3):552–4.PubMed
24.
Haffner R, Oren M. Biochemical properties and biological effects of p53. Curr Opin Genet Dev. 1995;5:84–90.PubMed
25.
Waga S, Hannon GJ, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature. 1994;369:574–8.PubMed
26.
Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ. p53-Independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science. 1995;267:1024–7.PubMed
27.
Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, Beach D, Lassar AB. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science. 1995;267(5200):1018–21.PubMed
28.
Shaulsky G, Goldfinger N, Peled A, Rotter V. Involvement of wild-type p53 in pre-B-cell differentiation in vitro. Proc Natl Acad Sci USA. 1991;88(20):8982–6.PubMedCentralPubMed
29.
Quang CT, Wessely O, Pironin M, Beug H, Ghysdael J. Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation. EMBO J. 1997;16(18):5639–53.PubMedCentralPubMed
30.
Metz T, Harris AW, Adams JM. Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes. Cell. 1995;82(1):29–36.PubMed
31.
Weiss MJ, Orkin SH. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci USA. 1995;92(21):9623–7.PubMedCentralPubMed
33.
Bloemendal H. Molecular and cellular biology of the eye lens. New York: Wiley; 1981.
34.
Piatigorsky J. Lens differentiation in vertebrates: a review of cellular and molecular features. Differentiation. 1981;19:134–53.PubMed
35.
Zhang L, Yan Q, Liu JP, Zou LJ, Liu J, Sun S, Deng M, Gong L, Ji WK, Li DW. Apoptosis: its functions and control in the ocular lens. Curr Mol Med. 2010;10(9):864–75.PubMed
36.
Cvekl A, Duncan MA. Genetic and epigenetic mechanisms of gene regulation during lens development. Progress Retinal Eye Res. 2007;26:555–97.
37.
Donehower LA, Harvey M, Slagle BL, McArthur MJ, Montgomery Jr CA, Butel JS, Bradley A. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature. 1992;356:215–21.PubMed
38.
Ikeda S, Hawes NL, Chang B, Avery CS, Smith RS, Nishina PM. Severe ocular abnormalities in C57BL/6 but not in 129/Sv p53-deficient mice. Invest Ophthalmol Vis Sci. 1999;40:1874–8.PubMed
39.
Reichel MB, Ali RR, D’Esposito F, Clarke AR, Luther PJ, Bhattacharya SS, Hunt DM. High frequency of persistent hyperplastic primary vitreous and cataracts in p53-deficient mice. Cell Death Differ. 1998;5:156–62.PubMed
40.
Deng M, Chen P, Liu F, Fu S, Tang H, Fu Y, Xiong Z, Hui S, Ji W, Zhang X, Zhang L, Gong L, Hu X, Hu W, Sun S, Liu J, Xiao L, Liu WB, Xiao YM, Liu SJ, Liu Y, Li DWC. The p53-Bak apoptotic signaling axis plays an essential role in regulating differentiation of the ocular lens. Curr Mol Med. 2012;12:901–16.PubMed
41.
Pokroy R, Tendler Y, Pollack A, Zinder O, Weisinger G. p53 Expression in the normal murine eye. Invest Ophthalmol Vis Sci. 2002;43:1736–41.PubMed