Hoarseness
590 (80.2%)
Breathing disorder
266 (36.1%)
Swallowing disorder
130 (17.7%)
Voice abnormality
541 (73.5%)
Breathing abnormality during exercise
308 (41.8%)
Breathing abnormality at rest
234 (31.8%)
Active papilloma growth
544 (73.9%)
Table 12.2
Sites of involvement
Above the vocal cords | 295 (40.1%) |
At the level of vocal cords | 597 (81.1%) |
Trachea | 136 (18.5%) |
Bronchi | 59 (8.0%) |
Lung | 32 (4.3%) |
Oral cavity | 7 (1.0%) |
Other head/neck regions | 2 (0.3%) |
Table 12.3
Adjuvant therapy outcomes – changes in voice quality
Adjuvant therapy | No. of patients | 0–12 months pre-start of adjuvant therapy | 0–12 months post-start adjuvant therapy | 12–24 months post-start adjuvant therapy |
|---|---|---|---|---|
DIM | 59 | 59 Good 10 (16.9%) Fair 23 (39.0%) Poor 26 (44.1%) | 53 Good 18 (34.0%) Fair 19 (35.8%) Poor 16 (30.2%) | 38 Good 13 (34.2%) Fair 16 (42.1%) Poor 9 (23.7%) |
Cidofovir | 97 | 97 Good 15 (15.5%) Fair 34 (35.1%) Poor 48 (49.5%) | 82 Good 26 (31.7%) Fair 31 (37.8%) Poor 25 (30.5%) | 74 Good 22 (29.7%) Fair 28 (37.8%) Poor 24 (32.4%) |
Table 12.4
VQOL: parents of children < 12 years old
Question | 1 | 2 | 3 | 4 | 5(worst) |
|---|---|---|---|---|---|
My child has trouble speaking loudly or being heard in noisy situations | 4 | 3 | 8 | 12 | 11 |
My child runs out of air and needs to take frequent breaths when talking | 11 | 11 | 7 | 7 | 2 |
My child sometimes does not know what will come out when he/she begins speaking | 13 | 9 | 11 | 3 | 1 |
My child is sometimes anxious or frustrated (because of his/her voice) | 8 | 7 | 6 | 10 | 7 |
My child sometimes gets depressed (because of his/her voice) | 16 | 10 | 5 | 3 | 4 |
My child has trouble using the telephone or speaking with friends in person (because of his/her voice) | 8 | 7 | 10 | 5 | 6 |
My child has trouble doing his/her job or schoolwork (because of his/her voice) | 17 | 8 | 6 | 4 | 2 |
My child avoids going out socially (because of his/her voice) | 24 | 4 | 5 | 1 | 3 |
My child has to repeat himself/herself to be understood | 4 | 5 | 6 | 10 | 13 |
My child has become less outgoing (because of his/her voice)
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