44 Vocal Fold Palsy • Brainstem—medulla nucleus ambiguus • Carotid sheath—between internal jugular vein and internal carotid artery • Left vagus crossing arch of aorta gives rise to left recurrent laryngeal nerve (RLN), which ascends in tracheoesophageal groove and then enters larynx at cricothyroid joint • Right vagus loops around subclavian artery to ascend to the larynx • RLN supplies motor fibres to all the muscles of the larynx except the cricothyroid muscle (which adducts the vocal cords) and sensation to the glottis/subglottis and trachea • The interarytenoid muscle (contraction causes approximation of the arytenoid muscles closing the posterior portion of the glottis) is the only muscle with bilateral innervation • A paralysed vocal fold (VF) may assume three positions: Adducted Abducted Paramedian • Theories that attempt to explain this: Semon law: recurrent laryngeal nerve palsy the abductors are affected before the adductors Wagner and Grossman hypothesis relates to cricothyroid activity Movement may be present of arytenoids despite VF palsy due to bilateral innervation of interarytenoid muscles • Presentation Hoarse voice Breathy voice Weak cough Difficulty in breathing Pain Choking with liquids—aspiration • Aetiology Congenital: hydrocephalus • Acquired: Iatrogenic surgery – Head and neck including thyroid – Vascular: carotid, cardiothoracic – Cervical spine and mediastinal operations • Intubation Malignancy: thyroid, laryngeal, lung, skull base or oesophageal cancers Trauma Idiopathic • Investigations Unknown aetiology: – Chest X-ray – CT skull base to mediastinum • Prognosis on recovery: Electromyelography—percutaneous placement of needle • Medical Better outcomes if VF is medialized • Surgical VF injection Laryngeal framework surgery • Injection laryngoplasty One-way procedure Can consider injection for patients with lung malignancy prior to treatment of cancer Local anaesthetic injection dependent on material type and respiratory status Present injectables: – Collagen: bovine extract decreasing use, check allergy status with intradermal injection before use – Hyaluronic acid: can inject percutaneously with 24/25-G needle; may last 4 months – Fat: requires abdominal fat harvest ± centrifuging, variable survival
44.1 Anatomy of Vagus/Recurrent Laryngeal Nerve
44.2 Unilateral Vocal Fold Palsy
44.2.1 Clinical Features (Fig. 44.1)
44.2.2 Diagnosis
44.2.3 Treatment
44.2.4 Surgical Treatment Options
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Vocal Fold Palsy
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