Glaucoma
–ICE Syndrome:
Iris Nevus (Cogan-Reese)
Chandler’s syndrome
Essential iris atrophy
DDx of glaucoma + uveitis:herpetic disease, Posner-Schlossman, Fuchs heterochromic iridocyclitis, sarcoid, toxoplasmosis, syphilis.
ISNT rule (nerve thickness from most to least)– Inferior rim, Superior, Nasal, Temporal.
–Homer-Wright rosetteis like a jelly donut that Homer Simpson would eat – the rosette has a filled center, no lumen (as opposed to Flexner-Wintersteiner rosette).
Parinaud’s syndrome: PARINAUDS
Papilledema
Accommodative insufficiency
Retraction of lid (Collier’s sign)
Insufficient convergence
Nystagmus
Aqueductal stenosis
Upgaze deficit
Dissociation of light-near response
Skew deviation
Hereditary optic neuropathies:Kjer’s, Behr’s, and Leber’s
Unilateral caloric stimulation (direction of fast jerk): COWS–Cold Opposite Warm Same.
Nerves LeFT out of the annulus of Zinn – LFTs:
Lacrimal
Frontal
Trochlea
Superior ophthalmic vein
Rhyme: “3, 4, SO, V1, 6. Through the SO Fix” – cranial nerves 3, 4, sympathetics, superior ophthalmic vein, branches of V1, cranial nerve 6.
Muscles affected by thyroid (in order of frequency):
“I M Stuart Little.”
Inferior
Medial
Superior
Lateral
Nodules
KoePpe nodules – Pupillary border
Busacca nodules – Mid Periphery
Berlin nodules – Iris Angle
Reiter’s Syndrome Can’t see, Can’t pee, Can’t climb a tree:Conjunctivits/irtis, urethritis, polyarthritis.
A11: Sympathetic Ophthalmia
A29: Birdshot
B5/B12: Behcet’s
B7: POHS, Serpiginous, Ankylosing spondylitis
B8: Sjogren’s, Sarcoidosis, intermediate uveitis
B12: OCP
B27: Ankylosing spondylitis, Reiter’s, IBD, Psoriatic arthritis
Bw54: Posner-Schlossman syndrome
DR4: VKH, OCP
JRA:ANA+, RF- (pauciarticular, females)
Meds that cause anterior uveitis/hypopyon:
Rifabutin, cidofovir
DDx of hypopyon:HLA-B27 uveitis, infection (keratits/endophthalmitis), foreign body, Behcet’s (rolling hypopyon), malignancy (leukemia, retinoblastoma), toxic (rifabutin)
Granulomatous uveitis: GLiB SHoTS
Granulomatous uveitis
Leptospirosis/Lyme
Brucellosis
Sarcoid
HSV
TB
Syphilis
DDx of iris heterochromia:Fuchs’ heterochromic iridocyclitis, trauma, retained IOFB, congenital Horner’s, iris melanoma, Posner-Schlossman, herpetic disease (iris atrophy), medications (prostaglandins), oculoder-mal melanocytosis
RAM GAP for duochrome test: if patient sees the Red half clearer, Add Minus. If the Green side is clearer, Add Plus.
Cloudy cornea at birth: Don’t get STUMPED!
Sclerocornea
Trauma
Ulcer
Mucopolysaccharidosis
Peters anomaly
Endothelial dystrophy (CHED)
Dermoid
MarylinMonroe Always Gets Her Man in L.A.
County(corneal dystrophies)
Macular
Mucopolysaccharide
Alcian blue
______________________
Granular dystrophy
Hyaline
Masson trichrome
______________________
Lattice Amyloid Congo red
-Bacteria that can penetrate intact corneas (they
create “CANALS”)
Corynebacteria
Aegyptus (Hemophilus)
Neisseria
Acanthaomoeba
Listeria
Shigella
Band keratopathy happens at the level of Bowman’s membrane
Terrien’s in Teens at Twelve:Terrien’s marginal degeneration occurs in the Teens and twenties and starts superiorly (at Twelve o’clock)
BIGH3 gene is LARGe (corneal dystrophies)
Lattice
Avellino
Reis-Bucklers
Granular
Interstitial Keratitis (IK): In Kenya, Cogan Saw Two
Laughing Hyenas Making Love
IK
Cogan’s syndrome
Syphilis
TB
Lyme/leprosy
Herpetic
Measles/Mumps
LGV/Leishmaniasis
-Fungal Keratitis demographics
North: Candida in Canada
South: Fusarium in Florida
DDx for Blue Sclera:Hurlers, Turner, Marfans, osteogenic imperfecta, staphyloma, oculodermal melanocytosis, Ehlers-Danlos, scleromalacia perforans
Central scarring
Oil drop reflex
Nerves prominent
Excessive bulging
Striae – Vogt’s
-MALE: transposition of muscles for A and V
patterns
Medial rectus toward the Apex
Lateral rectus toward the Empty space
Hermansky-Pudlak:Platelet defect, Puerto Ricans
-PEPSI: Angioid Streaks
Pseduoxanthoma elasticum
Ehlers Danlos
Paget’s disease of the bone
Sickle cell anemia
Idiopathic
-StARgARdt’s disease: Autosomal Recessive (AR)
-Female CARrier states (retinal changes): CAR
Choroideremia
Albinism
Retinitis pigmentosa
-Tuberous Sclerosis:Zits, Fits, Twits: sebaceous adenoma, seizures, mental retardation
-Melanoma: To Find Small Ocular Melanoma:
(likelihood of melanoma vs. nevus, 1 factor then
30% chance of progression, 3 factors then 50%
chance of progression)
Thickness >2 mm
Fluid
Symptoms
Orange pigment
Margin of optic nerve
-Stages of sickle retinopathy: NASVaR (like
NASCaR)
Nonperfusion
AV anastomoses
Sea-fan neovascularization
Vitreous hemorrhage
Retinal detachment
-Best’s disease:Chromosome 11 – imagine an egg yolk-like macular lesion with two strips of bacon (for the number 11).
-Choroidal folds: THIN RPE
Tumors
Hypotony
Inflammation/Idiopathic
Neovascular membrane
Retrobulbar mass
Papilledema
Extraocular hardware
-Crystalline retinopathy:(hydroxy-)chloroquine, tamoxifen, canthaxanthine, talc, methoxyflurane, Bietti’s, idiopathic juxtafoveal telangiectasia
-CME without leakage on FA:nicotinic acid maculopathy, Goldmann-Favre, retinoschisis