Diseases of the Oral Cavity and Oropharynx

47 Diseases of the Oral Cavity and Oropharynx


47.1 Oral Manifestations of Systemic Diseases


47.1.1 Infections


• Measles—Koplik spots


• Varicella zoster virus (VZV) (chickenpox)—vesicles


47.1.2 Inflammatory Disorders


• Behçet syndrome


figure Rare


figure Recurrent oral and genital ulcers


figure Ocular inflammation


• Reiter syndrome


figure Uncommon


figure Urethritis


figure Uveitis


figure Conjunctivitis


figure Arthritis


figure Tongue ulcers may be mistaken for geographic tongue


• Granulomatosis with polyangiitis


figure Gingival hyperplasia


figure Lingual, palatal, and buccal ulcers also common


• Erythema multiforme


figure Multiple erosions of lip and tongue


• Pemphigus/pemphigoid (Fig. 47.1)


figure Autoimmune vesicobullous disorders


figure 90% of pemphigus patients will have oral cavity involvement


• Kawasaki disease (mucocutaneous lymph node syndrome)


figure Strawberry tongue


figure Dry fissured lips


figure Pharyngeal injection


figure Necrotizing pharyngitis


• Sjögren syndrome


figure Keratoconjunctivitis


figure Xerostomia—ulcers of tongue, lips, and buccal mucosa


figure Arthritis


• SLE


figure Xerostomia


figure Petechiae, haemorrhagic bullae, and white keratotic plaques on tongue and oral mucosa


47.1.3 Miscellaneous Disorders


• Vitamin C deficiency (scurvy)


figure Swollen red gingival ulcerative oral petechiae ± haemorrhage


figure Stomatitis


• Vitamin B2 deficiency


figure Glossitis


figure Angular chelitis


figure Oral burning


• Vitamin B12/folate deficiency


figure Recurrent oral ulcers


figure Painful atrophy of oral mucosa and tongue


figure Necrotizing ulcerative gingivitis


figure Angular chelitis


• Thrombocytopaenia


figure Petechiae ecchymoses and haemorrhages


• Polycythemia


figure Purple-blue discolouration of tongue and gums


• Leukaemia


figure Gingival hypertrophy


47.2 Infections


47.2.1 Viral Infections


• Herpangia


figure Coxsackie viruses


figure Multiple small vesicles and superficial ulcers—posterior oropharynx


• Hand-foot-and-mouth disease


figure Coxsackie A virus


figure Anterior oral cavity


• Herpes simplex


figure Either primary or recurrent secondary


figure Common in preschool children


figure Diffuse bilateral lymphadenopathy common


figure Painful ulceration


figure Precipitating factors for recurrent type:


– Sunlight


– Fever


– Bacterial infections


– Stress


– Immunodeficiency


– Other systemic illness


• Herpes zoster (VZV)


figure Lesions along V2 and V3


figure Uncommon in infants and children


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Jul 4, 2016 | Posted by in OTOLARYNGOLOGY | Comments Off on Diseases of the Oral Cavity and Oropharynx

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