6 Evaluation of Refractive Error and Pre- and Postoperative Data

CHAPTER 6


Evaluation of Refractive Error and Pre- and Postoperative Data



Andrea D. Border, John F. Doane, Scot Morris, and James A. Denning


CHAPTER CONTENTS


Retinoscopy


Binocular Fog Manifest Refraction


Binocular Balancing


Trial Frame Refraction


Cycloplegic Retinoscopy and Refraction


Keratometry


Computerized Corneal Topography


Keratoscopy


Pachymetry


Specular Microscopy


Ultrasonic Scanning


High-Frequency Anterior Segment Ultrasound Biomicroscopy


Contrast Sensitivity Testing


Suggested Readings


Before undergoing refractive surgery, a candidate’s refractive error and other preoperative data, such as that from pachymetry and topography, must be evaluated to ensure consistent and accurate surgical results. Likewise, postoperative data need to be evaluated to decrease the likelihood of complications and to increase the possibility of favorable surgical results. Autorefraction may provide a useful starting point for baseline preoperative refraction but should not be used for postoperative testing because it often gives erroneous results (Fig. 6-1).


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Figure 6–1   The autorefractor by Humphrey gives spectacle refractive error and K values.


RETINOSCOPY


Indications



  • starting point for determination of a patient’s manifest refractive error (required of all refractive surgery candidates)

Methods



  • Enter the correct distance pupil diameter into the phoropter.
  • Place the phoropter in front of the patient, making sure it is level with the patient’s head.
  • Relax accommodation by “fogging” the patient with plus-power lenses, placing a moderate amount of spherical plus power over the patient’s habitual prescription into the phoropter (+1.50 to +2.00 D).
  • Present the 20/60 line of Snellen’s chart to each individual eye. (If the line is too blurry to read with either eye, the patient is adequately fogged.)
  • Present a 20/400 distance target (e.g., the “E” from Snellen’s chart) to the patient for fixation using both eyes (OU).
  • Perform retinoscopy one eye at a time while OU are unoccluded.
  • Do not remove the retinoscopic working-distance lenses (usually +1.50 D) from the phoropter (can trigger patient accommodation).
  • Adjust the working-distance lenses accordingly if you perform retinoscopy particularly close to or far from the phoropter.
  • Record the retinoscopic findings for comparison with manifest refraction results.
  • Note the retinoscopic reflex (should be bright and clear, not dull).
  • Note any “scissoring” of the reflex motion (a hallmark sign of keratoconus).
  • Proceed directly to binocular fog manifest refraction.

BINOCULAR FOG MANIFEST REFRACTION


Myopia



  • determination of refractive error with a phoropter after retinoscopy (for all patients)

Methods



Hyperopia


Indications



  • See section on myopia for indications.

Methods



  • The procedure for binocular fog manifest refraction of hyperopes is identical to that for myopes.
  • Follow the steps for myopic binocular fog manifest refraction carefully to reduce the chance of underestimating the true amount of plus power of the refraction. (Hyperopes may not accept full plus power on the manifest refraction end-point if they are not properly fogged, and even with proper fogging, they still may not accept the full amount of plus power discovered on retinoscopic evaluation (i.e., latent hyperopia.)
  • Proceed to a cycloplegic examination to reveal the actual amount of hyperopia for patients with suspected latent hyperopia.

Astigmatism


Indications



Methods



  • The procedure for astigmatic binocular fog manifest refraction is exactly the same as that described for myopic-binocular fog manifest refraction.
  • If you cannot reconcile retinoscopic results with manifest refraction results, perform a cycloplegic retinoscopy and manifest refraction.

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Figure 6-2   A topographical map shows a patient with nonorthogonal corneal astigmatism.


BINOCULAR BALANCING


Indications



Methods



Fogged Prism Disassociated Balance


Methods



  • Make sure both of the patient’s eyes are open behind the phoropter.
  • Fog each eye to slightly over the monocular endpoint obtained with binocular fog manifest refraction by +0.75 D sphere power (Fig. 6-3).
  • Isolate one or two acuity lines worse than the patient’s BCVA line on the projected distance chart.
  • Place three prism diopters base down (BD) over OD and three base up (BU) over OS using the phoropter’s rotary (Risley’s) prisms.
  • Inform the patient that he or she should see two “fuzzy” lines of letters, one above the other.

    • If the patient sees only one line, try increasing the vertical prism to four to six prism diopters over each eye and make sure OU are open.

  • If OU are open but the patient still sees only one line, abandon this balance procedure for one of the others described in this section.
  • Instruct the patient to look at both lines with OU and report if one line looks clearer or if both lines appear equally fuzzy. (If equally fuzzy initially, then the patient is already balanced and the procedure is complete.)
  • Add +0.25 D sphere power to the eye that sees the clearer line (i.e., make it blurrier). [If the lower line is clearer (the one seen by OS) then add +0.25 D to OS.]
  • Ask the patient again if both lines are equally blurry.
  • If not, ask the patient again which line is clearer and add +0.25 D to the eye seeing the clearer line.
  • The endpoint is reached when the patient reports that both lines are equally clear or nearly equally clear. (If the patient cannot decide which line is clearest, then the patient cannot be balanced and you should leave the patient’s dominant eye clearer by 0.25 D.)
  • After achieving the endpoint, remove the prisms and step down the patient from plus-sphere power until the patient can read the BCVA line sharply without noticing any binocular minification of the letters.
  • Record the resulting numbers for each eye as the patient’s manifest refraction.

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Figure 6-3   This patient has been fogged by +0.75 D over the manifest refraction result for OU for fogged prism disassociated balancing. To disassociate the patient’s eyes, three prism diopters BD have been placed over OD and three prism diopters BU have been placed over OS using the Risley’s prisms of the phoropter.


Red-Green Prism Disassociated Duochrome Balance


Indications



Methods



  • Unocclude OU behind the phoropter.
  • Isolate one line on Snellen’s chart that is larger than the patient’s BCVA line.
  • Do not fog either eye.
  • Cover the isolated line with the red-green filter.
  • Using the phoropter’s Risley’s prisms, place three prism diopters BD over OD, and three BU over OS.
  • Inform the patient that he or she should see two lines, one above the other.

    • If the patient sees only one line, make sure OU are open.
    • If patient’s eyes are both open, increase the vertical prism to 4 or 6 D over each eye.
    • If the patient still does not see two lines, invert the prisms (i.e., place BU over OD and BD over OS).
    • If the patient still cannot see two lines, abandon the procedure for one that does not involve prism disassociation, such as fogged alternate cover balancing.

  • Instruct the patient to look at the upper line only (the one seen by OD) while keeping OU open.

    • Tell the patient to look from the green side to the red side and then back to the green side.
    • Ask which side looks sharper and clearer or if both sides look equally clear.
    • If the green side is clearer, add -0.25 D to OD only; if the red side is clearer, add −l0.25 D to OD.
    • If both the red and green sides look equally clear initially, proceed to balancing OS (i.e., direct the patient to look at the lower line).

  • The endpoint for OD is achieved when both sides appear equally clear. (If both sides are not equally clear and the patient cannot decide which one is clearer, leave the green side clearer than the red side by 0.25 D.)
  • Direct the patient’s attention to the lower line (the one seen by OS), and repeat the steps described for OD using the same endpoint criterion.
  • If a patient always chooses the same side (red or green) as clearer regardless of which lens is presented, abandon the duochrome test for another balancing method.
  • Record the endpoints for OD/OS as the manifest refraction results.

Fogged Alternate Cover Balance


Indications



  • an alternative to fogged prism disassociated and red-green prism disassociated duochrome balance methods for patients unresponsive to those tests

Methods



image


Figure 6–4   This patient has been fogged by +0.75 D OU over the manifest refraction for fogged alternate cover binocular balancing. A cover paddle alternately covers each eye behind the phoropter.


TRIAL FRAME REFRACTION


Indications



  • “fine tuning” of the results of binocular fog manifest refraction and binocular balance (see pages 46 and 48, respectively) when a patient’s spherical equivalent refractive error is more than 4.00 D
  • confirmation of results from binocular fog manifest refraction for patients with accommodative instability (Vertex distance can be held constant and peripheral fusion cues are left intact in a trial frame although for patients with very deep-set or proptotic eyes, a trial frame may not achieve the average vertex distance.)
  • another option for retinoscopy and binocular fog manifest refraction on patients who are unable to sit behind a phoropter
  • generally more accurate refinement of refraction than the phoropter because you can control vertex distance and leave peripheral fusion locks intact

Methods



CYCLOPLEGIC RETINOSCOPY AND REFRACTION


Indications



Methods



  • Diligent fogging techniques are unnecessary for cycloplegic retinoscopy and manifest refraction.
  • Tropicamide (1%) (Mydriacil, Opticyl) is usually adequate when performing a cycloplegic examination on adult patients (Fig. 6-7)

    • In extreme cases of latent hyperopia or accommodative spasm, you may need to use stronger cycloplegic agents (cyclopentolate 0.5%).
    • Administer two drops of 1% tropicamide 10 minutes apart, and begin examination at least 20 minutes after administration of the last drop.

  • For cyclopentolate, the maximum duration of action is longer so it is best to wait 40 to 60 minutes before proceeding with the refractive examination.
  • In all cases, perform retinoscopy for a cycloplegic examination before manifest refraction behind the phoropter.

    • Record cycloplegic retinoscopic results for each eye.
    • Remove half of the retinoscopic working distance lenses (+0.75 D).

  • Occlude OS and perform monocular manifest refraction (MMR) on OD.

    • After reaching the MMR endpoint for OD, occlude OD and perform MMR on OS.

  • Record the cycloplegic MMR result and the corresponding distance visual acuity for each eye. (If cycloplegic results do not correspond with noncycloplegic results, rely more on the cycloplegic examination for refractive surgical data.)

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Figure 6-7   Two drops of Mydriacyl 1% (tropicamide), administered 10 minutes apart, is generally considered adequate for cycloplegic refraction of an adult patient.


KERATOMETRY


Indications



image


Figure 6-8   A patient being examined with a manual keratometer to diagnose the location, type, and amount of corneal cylinder. (Corneal mire quality can also be evaluated. It should be remembered that the keratometer only analyzes the central 3mm of the cornea.)


Methods (Fig. 6-8)



  • Place the patient’s head in the headrest of the keratometer.
  • Instruct patient to look at their eye reflected at the end of the tube.
  • With one of the patient’s eyes occluded, focus the mires of the keratometer on the cornea of the unoccluded eye.
  • Adjust the keratometer dials to achieve the correct alignment of the mires.
  • Read the keratometry (K) values from the dials.

COMPUTERIZED CORNEAL TOPOGRAPHY


Indications



  • far superior for most refractive surgical procedures because manual keratometry provides information about only the central 3 mm of the cornea
  • determines the amount, location, regularity, and type of corneal astigmatism (Figs. 6-9 and 6-10)
  • determination of central corneal power

    • helps select the best microkeratome for LASIK
    • helps determine pre- versus postoperative corneal changes
    • helps screen out excessively flat corneas that may not be best treated with refractive procedures that primarily involve further corneal flattening

  • screening out of preoperative corneal pathology
  • identifies forme fruste keratoconus, which often appears as a steep (> 47.00 D) inferior nasal apex with irregular astigmatism or! corneal topography [a contraindication for refractive surgery especially photorefractive keratectomy (PRK) and LASIK] (Fig. 6-11)

    • identification of individuals with suspected keratoconus (more than 2.5 D of variation between the superior and inferior K values)

  • evaluation of postoperative corneal condition

    • especially helps determine the presence or absence of central islands after excimer laser procedures, which are associated with residual myopia (Fig. 6-12)
    • helps determine the presence of a decentered ablation after laser refractive surgery (PRK or LASIK) (Fig. 6-13)
    • helps determine the presence of irregular corneal astigmatism following incisional keratotomy procedures, which may account for poor postoperative acuity

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Figure 6-9   A computer topographical printout shows a large amount of preoperative corneal “within-the-rule” astigmatism and the trend-with-time topographical maps after LASIK.


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Figure 6-10   A computer topographical printout of a cornea showing irregular astigmatism secondary to a corneal scar.


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Figure 6-11   A computer topographical printout showing an inferior, steep nasal apex (> 47.00 D). This patient has keratoconus.


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Figure 6-12   A topographical map of a cornea 3 weeks after LASIK that shows a steep central island. The patient showed residual myopia upon manifest refraction.


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Figure 6-13   A topographical map of a decentered laser ablation zone following LASIK.



Methods



  • Place the patient’s head in the headrest.
  • With one of the patient’s eyes occluded, focus and center the reflected images on the cornea of the unoccluded eye.
  • Capture and process the focused and centered image in the computer.

KERATOSCOPY


Indications



  • identification of corneal mires using a battery-powered, light-emitting diode device (Maloney or Van Loenen keratoscopes; JEDMED Instrument Company, St. Louis, MO) that attaches to a standard slit lamp for a magnified, coaxial view or is hand held
  • determination of corneal surface regularity and tear film quality for pre- and postoperative evaluations (corneal surface or tear film abnormalities indicated by irregular blurred mires a possible contraindication for some procedures because they suggest irregular astigmatism or keratoconus)

Methods



image


Figure 6-14   A computer printout of topographical analysis of a cornea that has poor quality tear film/surface interaction. Note the photokeratoscopic view (lower right) and the blurred, inconsistent mire circles reflected off the cornea.



  • Adjust the distance of the keratoscope from the eye until the mires are focused.
  • Note the configuration of the mires.

PACHYMETRY


Indications



image


Figure 6-15   A solid-state, ultrasonic pachymeter with digital display and memory.


Methods



  • Administer topical anesthesia (optional).
  • Take multiple pachymetric readings to ensure consistency.
  • Follow the manufacturer’s suggested protocol for use and maintenance (Zeiss Humphrey Systems or Sonogage.)

SPECULAR MICROSCOPY


Indications



image


Figure 6-16   Corneal gutatta.


ULTRASONIC SCANNING


A-Scans


Indications



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Figure 6-17   A typical ultrasound A/B-scan unit.


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Figure 6-18   An applanation A-scan technique being performed on a patient with mounted probe.


APPLANATION A-SCANS


Indications



IMMERSION A-SCANS


Indications



  • generally better accuracy because of lack of corneal indentation but slightly more complicated to operate than an applanation A-scan because of the need of creating an immersion waterbath over the eye
  • possibility of poor echo readings with extra fluid around the eye because the ultrasound waves must travel through more dense media to get to the eye

Methods



  • Place a water bath around the eye to avoid direct corneal indentation (Fig. 6-19).
  • Take multiple measurements to ensure consistancy.

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Figure 6-19   Immersion A-scan technique being performed on a patient by a technician.


B-Scans


Indications



Methods



  • Put an electronic mark on the apex of the cornea (possible with most B-scan units).
  • For eyes with an axial length of more than 26.5 mm, measure 4.5 mm temporally from the center of the optic nerve and place another electronic mark at that point on the retina for each eye (the center of the optic nerve and the fovea are about 4.5 mm apart).
  • The difference between the two electronic marks is the “true” axial length of the eye, the distance between the fovea and the corneal apex instead of the distance between the posterior portion of the staphyloma and the corneal apex.
  • Repeat for the other eye.

HIGH-FREQUENCY ANTERIOR SEGMENT ULTRASOUND BIOMICROSCOPY


Indications



  • determination of the exact anatomical relationship among the posterior iris and anterior lens capsule, anterior chamber depth, and anterior chamber angle anatomy
  • preoperative evaluation for implantation of an intraocular contact lens (ICL) behind the iris and in front of the natural lens to correct myopic or hyperopic refractive error while still allowing for accommodation (STAAR Surgical Co., Monrovia, CA; currently undergoing investigative trials)

Methods



CONTRAST SENSITIVITY TESTING


Indications



Methods



  • Follow the manufacturer’s suggested instructions for use and grading (provided with test).
  • Perform distance contrast sensitivity testing 10 feet from the chart.
  • Perform near testing usually 18 inches from the chart.
  • Perform contrast sensitivity testing near and at distance with and without correction; in dim and bright lighting.

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Figure 6-20   A remote-controlled contrast sensitivity chart with background illumination.


Suggested Readings


Assil KK, Schanzlin DJ. Radial and Astigmatic Keratotomy: A Complete Handbook. St. Louis, MO: Poole Press; 1994.


Carlson NS, Kurtz D, Heath DA, Hines C. Clinical Procedures for Ocular Examination. Norwalk, CT: Appleton & Lange; 1990.


Holladay JT. Why the A-scan is your key to better cataract care. Rev Optometry. 1999; 30:85-88.


Machat JJ, Slade SG, Probst LE. The Art of LASIX. 2nd ed. Thorofare, NJ: Slack Inc.; 1999.


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Jul 24, 2016 | Posted by in OPHTHALMOLOGY | Comments Off on 6 Evaluation of Refractive Error and Pre- and Postoperative Data

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