23.2

Vitreoretinal Lymphoma

Introduction:

Primary vitreoretinal lymphoma (VRL) is an uncommon form of primary central nervous system lymphoma. Typically it is a malignant B-cell non-Hodgkin lymphoma. Ninety per cent of affected patients eventually develop concurrent central nervous system involvement. The prognosis for survival historically has been poor but more recently seems to be improving.

Clinical Features:

There are no clinical pathognomonic features of VRL and confirmation of the diagnosis can be difficult as it typically presents as an unspecified posterior uveitis. In certain cases, lymphoma cells can invade the subretinal space, leading to characteristic multifocal, dome-shaped yellowish subretinal deposits. These can be located within the macula, but are most striking when located in the retinal periphery (Fig. 23.2.1).

Figure 23.2.1

Only gold members can continue reading. Log In or Register to continue

Share this:

• Click to share on Twitter (Opens in new window)
• Click to share on Facebook (Opens in new window)

Related

Related posts:

1. Central Serous Chorioretinopathy
2. Central Retinal Artery Occlusion
3. Birdshot Chorioretinopathy
4. Choroidal Melanoma

Stay updated, free articles. Join our Telegram channel

Join

Full access? Get Clinical Tree