22.2

Retinoblastoma

Introduction:

Retinoblastoma is the most common pediatric intraocular malignancy, representing about 5% of all pediatric malignancies.

Clinical Features:

The most common presenting feature is leukocoria, but others include strabismus, decreased vision, and a painful eye. Characteristic clinical features include a white or yellow-white elevated, fungating, singular or multifocal retinal tumor (Fig. 22.2.1). Associated vitreous and subretinal seeding may also be present.

Figure 22.2.1 Color photograph of retinoblastoma in an infant shows two separate lesions involving the posterior pole of differing sizes. Both are round, elevated, and creamy-white in color. (Courtesy of Carol Shields, MD.)

OCT Features:

OCT shows involvement of the neurosensory retina, particularly the photoreceptors

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Related

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1. Central Serous Chorioretinopathy
2. Central Retinal Artery Occlusion
3. Metastatic Choroidal Tumor
4. Choroidal Melanoma

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