S.no
First author
Journal/year
Type of study
Disease
No
Location
Method of treatment
Assessment of response
Anatomical outcome
Visual outcome
Follow up
Remarks
1
Nielsen [14]
Retina-2012
Retrospective
POHS
54 eyes
pp, ef, jf, sf
IVB or IVR (PRN)
VA
–
96.2 % eyes: improvement
1 year
2
Arevalo [15]
Retina-2011
Retrospective, interventional
Inflammatory chorioretinal diseases
23 eyes
pp, ef, jf, sf
IVB 1.25 or 2.5 mg (PRN)
CMT, VA
Regression in all
Stable or improved in 91.3 %
2 years
No difference in response noted in 1.25 or 25 mg group
3
Kramer [16]
Retina-2010
Retrospective, interventional
”
10 eyes
pp, ef, jf, sf
IVB 2.5 mg (PRN)
CMT, VA
Regression in all
Improved in 90 %
Mean: 13 ± 8 months
Concomitant immunosuppression given where necessary
4
Fine [17]
Retina-2009
Retrospective, interventional
MFC
6 eyes
pp, ef, jf, sf
IVB and/or IVR (PRN)
VA
Regression in all
Improved in 83.3 %
6 months
Concomitant immunosuppression given where necessary
5
Mansour [18]
AJO-2009
Retrospective, interventional
Inflammatory chorioretinal diseases
99 eyes
pp, ef, jf, sf
IVB 1.2 5 mg (PRN)
CMT, VA
No regression in 31.6 % eyes with MFC, 4.3 % eyes with PIC
Mean VA improvement of >2.2 lines
2 years
6
Menezo [19]
Retina-2010
Retrospective
PIC
10 eyes
pp, ef, jf, sf
IVR (PRN)
VA
Significant CMT reduction in all
9/10 eyes: VA stable or improved >1 line
6 months
Table 12.2
Table summarizing studies using anti-VEGF and PDT for the treatment of inflammatory CNV
S.no | First author | Journal/year | Type of study | Disease | No | Location | Method of treatment | Assessment of response | Artatomical outcome | Visual outcome | Fallow up | Remarks |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Chan [13] | Retina-2008 | Prospective | PIC | 14 eyes | sf | PDT + IVTA (PRN) | VA | Regression in all | 92.9 % stable/improved VA | 1 year | |
2 | Cionni [20] | Ophthalmology-2012 | Retrospective comparative | POHS | 150 eyes | sf, jf | IVB mono therapy or IVB + PDT (PRN) | VA | Regression in all | 81.2 % stable/improved at; end of 1 year | Mean follow up 21.1 months | No significant; difference in VA outcomes between the two groups |
Table 12.3
Table summarizing studies comparing use of anti-VEGF versus PDT for the treatment of inflammatory CNV
S.no | First author | Journal/year | Type of study | Disease | No | Location | Method of treatment
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