25 Complications of Sinusitis • Divided into orbital (60–75%), intracranial (15–20%), and osseous (5–10%) complications • Sinus disease accounts for: • Incidence of complications: • More common during winter months • Males > females • Antibiotics for ARS do not change the incidence of complications • Most common type of complication • Associated with ethmoid, maxillary, frontal, sphenoid in reducing frequency • Chandler classification (Fig. 25.1) • An ophthalmology review is mandatory • IV antibiotics covering aerobic and anaerobic organisms • Presence of ophthalmoplegia, loss of red–green vision/visual acuity—CT with contrast required → surgical drainage • No improvement/deterioration after 48 h IV antibiotics → surgical drainage • CT appearance: – Medial rectus oedema – Lateralization of medial rectus/periorbita – Globe displacement inferolaterally – Loss of detail of extraocular muscles/optic nerve – Possible orbital air • Surgical drainage should also include addressing the adjacent sinuses • Some evidence to suggest in small children with subperiosteal abscesses IV antibiotics sufficient if: • Spread from sinuses through diploic veins or directly through bone erosion • Often involve anaerobic or mixed aerobic/anaerobic organisms • These include: • Symptoms: • Investigations • Treatment • Venous drainage of paranasal sinuses to cavernous sinus—allows haematogenous spread of infection
25.1 Complications of Acute Sinusitis
10% of intracranial suppuration
10% of pre-septal orbital infection
90% of post-septal orbital infection
2.7 to 4.3 per million (intracranial complications)
2.5 per million adults (all acute rhinosinusitis (ARS) complications)
1 per 12,000 ARS episodes (children)
1 per 36,000 ARS episodes (adults)
25.1.1 Orbital Complications
I—pre-septal cellulitis (strictly speaking, outside the orbit)
II—orbital cellulitis
III—subperiosteal abscess
IV—orbital abscess
V—cavernous sinus thrombosis (again, not “orbital,” and not necessarily the end stage of orbital infection)
Subperiosteal abscess:
Orbital abscess:
Improving over 48 h
Normal visual acuity
<1 mL volume, medial location
<4 years of age
Systemically well
25.1.2 Intracranial Complications
Epidural, subdural, cerebral abscesses
Meningitis, encephalitis
Superior sagittal, cavernous sinus thrombosis
Nausea and vomiting
Neck stiffness
Altered mental state
Focal neurological deficits
Headache
CT scan with contrast—bone erosion
MRI—soft tissue involvement, cavernous sinus thrombosis
Consider lumbar puncture
Long-term, high-dose IV antibiotics
Craniotomy and abscess drainage
Endoscopic drainage of sinuses
MC&S of pus, biopsy of abnormal tissue
25.1.3 Cavernous Sinus Thrombosis
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