25 Complications of Sinusitis • Divided into orbital (60–75%), intracranial (15–20%), and osseous (5–10%) complications • Sinus disease accounts for: 10% of intracranial suppuration 10% of pre-septal orbital infection 90% of post-septal orbital infection • Incidence of complications: 2.7 to 4.3 per million (intracranial complications) 2.5 per million adults (all acute rhinosinusitis (ARS) complications) 1 per 12,000 ARS episodes (children) 1 per 36,000 ARS episodes (adults) • More common during winter months • Males > females • Antibiotics for ARS do not change the incidence of complications • Most common type of complication • Associated with ethmoid, maxillary, frontal, sphenoid in reducing frequency • Chandler classification (Fig. 25.1) I—pre-septal cellulitis (strictly speaking, outside the orbit) II—orbital cellulitis III—subperiosteal abscess IV—orbital abscess V—cavernous sinus thrombosis (again, not “orbital,” and not necessarily the end stage of orbital infection) • An ophthalmology review is mandatory • IV antibiotics covering aerobic and anaerobic organisms • Presence of ophthalmoplegia, loss of red–green vision/visual acuity—CT with contrast required → surgical drainage • No improvement/deterioration after 48 h IV antibiotics → surgical drainage • CT appearance: Subperiosteal abscess: – Medial rectus oedema – Lateralization of medial rectus/periorbita – Globe displacement inferolaterally Orbital abscess: – Loss of detail of extraocular muscles/optic nerve – Possible orbital air • Surgical drainage should also include addressing the adjacent sinuses • Some evidence to suggest in small children with subperiosteal abscesses IV antibiotics sufficient if: Improving over 48 h Normal visual acuity <1 mL volume, medial location <4 years of age Systemically well • Spread from sinuses through diploic veins or directly through bone erosion • Often involve anaerobic or mixed aerobic/anaerobic organisms • These include: Epidural, subdural, cerebral abscesses Meningitis, encephalitis Superior sagittal, cavernous sinus thrombosis • Symptoms: Nausea and vomiting Neck stiffness Altered mental state Focal neurological deficits Headache • Investigations CT scan with contrast—bone erosion MRI—soft tissue involvement, cavernous sinus thrombosis Consider lumbar puncture • Treatment Long-term, high-dose IV antibiotics Craniotomy and abscess drainage Endoscopic drainage of sinuses MC&S of pus, biopsy of abnormal tissue • Venous drainage of paranasal sinuses to cavernous sinus—allows haematogenous spread of infection
25.1 Complications of Acute Sinusitis
25.1.1 Orbital Complications
25.1.2 Intracranial Complications
25.1.3 Cavernous Sinus Thrombosis
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Complications of Sinusitis
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