18.5 ARN commonly presents with multifocal peripheral areas of full-thickness retinal necrosis in well-circumscribed patches that rapidly coalesce in a circumferential pattern (Fig. 18.5.1). There is an associated brisk intraocular inflammatory reaction and an occlusive vasculitis that primarily affects the retinal arteries. Vitritis is universal and a mild anterior chamber reaction with keratic precipitates is typical. Elevated intraocular pressure is not unusual. Without treatment, spread is rapid and may also involve the fellow eye.
Acute Retinal Necrosis Syndrome
Clinical Features:
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