Rhinoscleroma is a rare infectious disease of the upper respiratory tract caused by Klebsiella rhinoscleromatis. There are five endemic regions including Eastern Europe, South America, Africa, India, and Indonesia. The infection usually starts in the nasal mucosa as transmission is thought to be by airborne droplet spread. The disease can be subdivided into three different stages. The first stage is associated with rhinorrhoea and crusting in the nasal cavity lasting months (11.1). The second stage is characterized by nodular granulomatous masses appearing within the nasal cavity, and these may extend to sinuses, nasopharynx, oropharynx, larynx, and tracheobronchial tree. The third sclerotic stage is characterized by healing that occurs with extensive scarring and adhesions around the nose, palate, and larynx (11.2). Subglottic stenosis can occur as a lifethreatening late manifestation requiring immediate surgical intervention (11.3). The diagnosis has to be confirmed with biopsy and histopathological examination. Medical treatment primarily consists of a long-term course of antibiotics. Tetracycline and ciprofloxacin have proved to be the most effective drugs.