Fig. 13.1
Left eye of a 91-year-old woman with central retinal vein occlusion, first diagnosed 5 years ago, with a history of recurrent cystoid macular edema treated with multiple intravitreal anti-VEGF injections. (a) Color fundus photography. (b) Infra-red fundus image. (c) SS-OCTA of the superficial retinal layer with enlargement of the foveal avascular zone (FAZ) area and with capillary discontinuity perifoveally and temporal to the macula. (d) SS-OCTA of the deep retinal layer also shows an enlargement of the FAZ area, areas of capillary discontinuity, and dilation of superior macular capillaries with increased signal as a sign for vascular congestion. (e, f) Show the corresponding segmentation
Fig. 13.2
A 56-year-old patient with central retinal vein occlusion in the left eye, which had first developed 1 year earlier. The patient has a history of recurrent macula edema treated with multiple anti-VEGF injections. (a) Color fundus photography. (b) Early and (c) late fluorescein angiography frames. (d) Structural optical coherence tomography (OCT) demonstrates cystoid macular edema. (e) SS-OCTA of the superficial retinal layer with enlargement of the foveal avascular zone (FAZ) area, capillary discontinuity and intraretinal cysts (dashed circle). (f) SS-OCTA of the deep retinal layer also shows an enlargement of the FAZ area, areas of capillary discontinuity and intraretinal cysts (dashed circle). (g, h) Show the corresponding slab segmentation
Fig. 13.3
A 79-year-old male with central retinal vein occlusion in the left eye. (a) Color fundus photography. (b) Early and (c) late fluorescein angiography frames. (d) Structural OCT. (e, f) SS-OCTA of the superficial and deep retinal layer with moderate enlargement of the foveal avascular zone area, some continuity of the perifoveal capillary network, and attenuation of the macular microvasculature. (g, h) Show the corresponding slab segmentation
13.2 Choroid
Changes in choroidal thickness in the eyes of patients with retinal vein occlusion have been previously described using enhanced depth imaging OCT. Tsuiki et al. [5], for example, observed increased choroidal thickness subfoveally in patients with central RVO, whereas others were only able to demonstrate increased choroidal thickness in the territory of the vascular occlusion. We have not observed significant alterations in the choriocapillaris or choroid by SS-OCTA in eyes with RVO; however, the edema from occlusion may cause a loss of signal that impairs the quality of the SS-OCTA.