Fig. 5.1
A color fundus photograph of a case of dot pseudodrusen. A few pseudodrusen were documented
Fig. 5.2
One year later in the same eye, increased pseudodrusen were observed
Fig. 5.3
Blue reflectance SLO image. The contour of individual pseudodrusen were clearly defined
Fig. 5.4
SS-OCT image. Triangular or rounded hyperreflective deposits located in the outer retina. Note that the different stages of pseudodrusen were detected in this single scan image. Dashed arrow, arrow heads, and arrows indicate stage 1, 2, and 3 pseudodrusen respectively, according to the classification of Zweifel et al.
Fig. 5.5
A color-coded choroidal thickness map created from SS-OCT radial scans. Note that most parts of the macula are occupied with thin choroid
5.3 Clinical Implications
A prospective cohort study of subjects with unilateral choroidal neovascularization (CNV) and large soft drusen found that their fellow eyes with pseudodrusen at baseline have higher incidence of developing advanced AMD after 3 years of follow-up, as compared to those without pseudodrusen at baseline [6] (Figs. 5.6, 5.7, 5.8, 5.9, 5.10 and 5.11).
Fig. 5.6
Color fundus photographs of a case of a combination of ribbon and dot pseudodrusen ((a), right eye; (b), left eye)
Fig. 5.7
Fundus autofluorescence images ((a), right eye; (b), left eye). A combination of ribbon and dot pseudodrusen exhibit hyporeflectivity (area within the line)
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