16 Management of Thyroid-Related Eyelid Retraction
Retraction of the eyelids is one of the most common ophthalmic manifestations of Graves’ disease. This malposition may occur with or without exophthalmos and is responsible for functional and cosmetic problems in many patients with thyroid-related eye disease. The etiology of eyelid retraction in Graves’ disease is not clearly understood, but several factors seem to be contributory. In the upper lid, these factors include (a) Müller’s muscle overaction from sympathetic stimulation, (b) levator contraction from degeneration and thickening of the levator muscle or the aponeurosis, (c) levator adhesions to the orbicularis muscle and orbital septum, and (d) overaction of the levator–superior rectus complex in response to a hypophoria produced by fibrosis and retraction of the inferior rectus.
In the lower eyelid, adrenergic stimulation of the Müller’s muscle plays a smaller role, but fibrosis of the inferior rectus exerting a retraction action on the lower eyelid through its capsulopalpebral head appears to be more influential.
SURGICAL INDICATIONS
Surgical treatment of eyelid retraction is usually reserved for patients whose endocrine status and eyelid height have been stable for at least 6 months to 1 year, and in whom retraction causes significant exposure keratopathy, lagophthalmos, chronic conjunctival injection, and cosmetic imperfection.
Several surgical procedures have been described to bring the retracted upper eyelid downward. These included levator tenotomy or recession, Müller’s muscle resection or myectomy, and combined levator tenotomy and mullerectomy. However, the aponeurotic approach described by Harvey and Anderson (1981) is preferred because it is anatomically, surgically, and physiologically sound. In this technique, the Müller’s muscle is completely extirpated, the lateral horn of the levator severed, and the aponeurosis recessed. Additionally, this anatomic approach is similar to that used in aponeurotic ptosis surgery.
Upper eyelid
Local anesthesia is preferable whenever feasible. This permits lid height, contour, and symmetry to be adjusted intraoperatively. A full-face preparation is given, and the head is draped with 3-M 1,000 surgical drape. The use of an open-face adhesive drape allows the patient to sit up in the middle of the surgery for lid height adjustment, without having to constantly adjust any loose head drape during this maneuver.
The normal skin crease is marked with a fine-tipped marking pen. For unilateral retraction cases, the skin crease is marked to correspond with the natural crease contour of the contralateral upper eyelid. Topical tetracaine may be instilled into the upper cul-de-sac intermittently throughout the procedure. Subcutaneous infiltration of lidocaine 2% with 1:100,000 epinephrine is given along the preplaced marking with a 30-gauge needle. The anesthetic solution should be delivered slowly to minimize patient discomfort, and no more than 1.5 ml is needed. A swollen lid will render fine lid height and contour adjustments suboptimal later on in the procedure.
A 4–0 double-armed silk traction suture is placed in the central margin of the upper lid and anchored to the surgical drape inferiorly with a hemostat. The needle is passed through the tarsal plate in a lamellar fashion, avoiding the marginal arcade and preventing unnecessary bleeding. When secured inferiorly, this traction suture puts all lid structures posterior to the orbicularis on stretch, while allowing the overlying skin and orbicularis to be mobilized. The skin is incised along the preplaced lid crease marking with a scalpel. All bleeding points are cauterized with a bipolar cautery.
The skin and orbicularis are grasped with a forceps on both sides of the incision centrally.