Investigative Modalities



Fig. 4.1
AS-OCT shows area of inflammation with edema and gross separation of the collagen fibers





Necrotizing Anterior Scleritis

This condition is characterized by the destruction of the collagen fibers and the thinning of the sclera. The posterior scleral surface is easily observed with irregularly arranged and dense reflective collagen fibers [22].


Nodular Anterior Scleritis

This condition is marked by the hyporeflective nodule surrounded by the hyperreflective sclera. AS-OCT clearly illustrates the swollen tissue mixed with the blood vessels and the inflammatory cells (Fig. 4.2) [22].

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Fig. 4.2
AS-OCT demonstrating hyporeflective nodule surrounded by hyperreflective sclera

The advent of SD-OCT has proved to be of significant improvement in increasing the sensitivity of diagnosis. It also helps in monitoring the disease progression in scleral disease and to monitor changes postoperatively (Fig. 4.3).

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Fig. 4.3
AS-OCT showing resolution of edema and inflammation post patch graft


Ultrasonography

The B mode ultrasonography is helpful in imaging both anterior and posterior scleritis. However, its main role is in monitoring the posterior scleritis. The retinal, choroidal, and scleral complex is seen as the heterogenous layer surrounded by the echogenic orbital fat and the echolucent vitreous. In posterior scleritis, there is reduction in echogenecity of the posterior coats of the eyeball. The fluid in Tenon’s capsule and the optic nerve sheath gives rise to the “T-sign”. The vertical bar of the ‘T’ being formed by the dilated optic nerve which is echolucent and the horizontal bar formed by the echolucent tenon’s fluid.


Computerized Tomography Scan

CT scanning utilizes the X-rays to generate the cross-sectional scans of the eye and the orbit [23]. It is particularly useful in the presence of granulomatous scleritis where there is destruction of the bone or the sinus infiltration. It is however, unsuitable for monitoring the course of the disease as it employs the X-rays [23].



Conclusions


Use of investigations could be classified into various categories based on the type of test, the level at which it needs to be considered, what information is expected, and how the results should be interpreted.


Compliance with Ethical Requirements

Divya Singh, Anat Galor and Radhika Tandon declare that they have no conflict of interest. No human or animal studies were carried out by the authors for this chapter.


References



1.

Yagci A. Update on peripheral ulcerative keratitis. Clin Ophthalmol. 2012;6:747–54.CrossRefPubMedPubMedCentral

Jun 25, 2017 | Posted by in OPHTHALMOLOGY | Comments Off on Investigative Modalities

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