High Frequency Of Submicroscopic Chromosomal Deletions in Patients with Idiopathic Congenital Eye Malformations

Purpose

The purpose of this study was to evaluate the clinical usefulness of the array comparative genomic hybridization technique for the genetic analysis of patients with congenital ocular malformations.

Design

Laboratory investigation.

Methods

This was a multicenter study. Samples were collected from 37 patients with negative results for the routine diagnostic work-up, including normal karyotype and mutation analysis of appropriate genes. Samples from both parents also were tested. High-resolution genome-wide Agilent 244K oligoarray (Agilent Technologies) was applied. Confirmation of the results was obtained with independent techniques.

Results

Causal deletions were identified in 5 (13%) patients, affecting OTX2 , FOXC1 and VPS13B ( COH1 ), the downstream regulatory region of PAX6 , and a 1,5 Megabases de novo deletion on chromosome 16.

Conclusions

This high frequency of causal submicroscopic chromosomal aberrations in patients with congenital ocular malformation warrants implementation of array comparative genomic hybridization in the diagnostic work-up of these patients. Moreover, this screening technique broadens the phenotypic and mutational spectrum associated with genes known to cause congenital ocular malformation.

Congenital ocular malformations are present in 4 to 6 in 10 000 newborns ( http://www.eurocat.ulster.ac.uk/ ) and are among the most frequent causes for childhood blindness. The cause of the congenital eye anomalies often is genetic. To identify the genetic defect, mutation screening of certain genes is offered to patients with specific phenotypes. In patients with isolated microphthalmia or anophthalmia, SIX3 , VSX2 , SOX2 , and OTX2 are tested most often. Anterior chamber dysgenesis and aniridia are indications for the analysis of PITX2 , FOXC1 , and PAX6 . Patients meeting the criteria for CHARGE association (Coloboma, Heart anomaly, choanal Atresia, Retardation, Genital and Ear anomalies) syndrome are investigated for CHD7 , and patients with renal coloboma syndrome are investigated for PAX2 mutations. A summary of the genes and their corresponding ocular phenotypes is provided elsewhere. For some congenital ocular malformations, such as aniridia, the current genetic testing provides a diagnosis for most patients. However, more than 80% of the patients with microphthalmia, anophthalmia, and coloboma remain without etiological diagnosis.

Epidemiologic studies reveal that chromosomal abnormalities are found in 7.7% to 10% of newborns with eye anomalies and other organ anomalies. Trisomies 13 and 18 commonly are reported in newborns with microphthalmia or anophthalmia. Partial duplication of 22q (Cat eye syndrome) and some segmental deletions—4p16 (Wolf Hirshhorn syndrome), 7q36, and 11p13 (WAGR [Wilmd tumour, Aniridia, Genitourinary anomalies, Retardation] syndrome)—are associated with coloboma and aniridia. Small deletions affecting only 1 gene or part of a gene occasionally have been identified in patients with eye malformations.

The conventional method for screening chromosomal aberrations is metaphase karyotyping. However, only imbalances of more than 5 megabases routinely are detected. When a specific microdeletion or microduplication syndrome is suspected, targeted techniques such as, for example, fluorescent in situ hybridization or multiplex ligation probe amplification can be applied. These methods can detect smaller aberrations, but are restricted to a specific locus. Array comparative genomic hybridization or molecular karyotyping combines the genome-wide screening capacity of karyotyping with the increased resolution of targeted techniques. The resolution of the different array platforms varies from 1 Mb to less than 50 kb. The method has been implemented in the diagnostic analysis of patients with syndromic mental retardation and has a diagnostic yield of up to 17%. Sporadically, submicroscopic imbalances in patients with congenital ocular malformations have been detected.

Based on the sporadic association of eye malformations with submicroscopic imbalances and the regular finding of chromosomal imbalances in patients with syndromic congenital ocular malformation, we hypothesized that small pathogenic chromosomal deletions and duplications may be uncovered in patients with idiopathic eye anomalies. To investigate this, we systematically analyzed 37 patients using high-resolution array comparative genomic hybridization.

Methods

Patients were recruited from clinical centers in Leuven, Belgium, and Madrid, Spain. The criteria for selection were the presence of a congenital ocular anomaly and negative routine diagnostic work-up results, including normal karyotype. Details on the performed investigations are available in Table 1 . In this group were 21 patients with microphthalmia, anophthalmia, and coloboma, 6 with syndromic retinal dystrophy, 5 with anterior chamber anomalies, 2 with cataract, and 3 with other eye malfomations such as Duane syndrome, ptosis, and severe myopia. The patients were examined by experienced ophthalmologists and clinical geneticists, and recognizable microdeletion and microduplication syndromes were excluded in selected patients. Routine mutation screening was carried out where appropriate ( Table 1 ). Deoxyribonucleic acid (DNA) was isolated from blood following the standard procedure. For all patients, DNA from both parents was available. DNA extracted from cell lines derived from anonymous healthy adults was used as a reference sample in the array comparative genomic hybridization experiments.

TABLE 1

Phenotypes and Diagnostic Work-up of the Patients with Congenital Ocular Malformations Included in the Study

No.	Ocular Phenotype	Other Anomalies	Familial	Preliminary Diagnostic Work-up
1	Unilateral Mi	MR, dysmorphism, cleft	No	0
2	Coloboma		No	PAX6 – seq and MLPA
3	Coloboma		No	PAX6 , SOX2 , OTX2 – DHLPC
4	Coloboma	Skeletal anomalies	Yes	TBX5 , SALL 4 – seq
5	Coloboma, lens subluxation		No	0
6	L Coloboma	Left ear dysplasia	No	0
7	Coloboma		Yes	SOX2 , PAX2 , SOX21 , SOX14 – DHPLC , PAX6 seq and MLPA
8	Coloboma	Autism	No	0
9	Iris Coloboma	Tetralogy of Fallot, feet anomalies	No	0
10	Coloboma	Cardiac anomaly, MR, dysmorphism	Yes	0
11	Coloboma		Yes	0
12	Coloboma		Yes	PAX6 , PAX2 , VSX2 , SOX2 , SOX3 , SOX14 , SOX21 , SHH , SIX6 , OTX2
13	Mi	Miscarriages in the family	Yes
14	Coloboma	Severe MR	No	PAX6 , SOX2 , OTX1 , SOX1 , PAX2 , SOX21 , SOX14 – seq
15	Coloboma		No	SIX6 , SIX3 , OTX2 , SOX2 – seq; OTX2 , SOX2 – MLPA
16	Coloboma, Mi	MR, hearing loss, equilibrium disturbances, tracheomalacia	No	CHD7 , SIX6 , SIX3 , OTX2 , SOX2 – seq; OTX2 , SOX2 – MLPA
17	Coloboma	Renal hypoplasia	No	SIX6 , SIX3 , OTX2 , SOX2 – seq; OTX2 , SOX2 – MLPA
18	Retinal and choroid coloboma		No	OTX2 , SOX2 – MLPA
19	Iris and retinal coloboma, microcornea		No	SOX2 – seq; OTX2 , SOX2 – MLPA
20	Optical nerve coloboma	Hypotonia	No	SIX6 , SIX3 , OTX2 , SOX2 ; MLPA OTX2 , SOX2 – seq
21	R An, L Mi		No	0
22	RP, myopia	MR, dysmorphism, microcephaly	No	0
23	RD, PHPV		No	0
24	Cone–rod dystrophy	Severe MR	No	0
25	RD	WEST syndrome	No	ARX – seq
26	RD	MR, microcephaly, myopia	No	0
27	RD		No	0
28	Asa		No	PAX6, FOXC1, PITX2 – seq and MLPA;
29	Asa		No (twin)	PAX6, FOXC1, PITX2 – seq and MLPA
30	Asa, glaucoma		No	FOXC1, PITX2 – seq and MLPA
31	Aniridia	MR, dysmorphism	No	PAX6 – seq; FOXC1, PITX2 – MLPA
32	Aniridia, glaucoma, buphthalmos	Club foot, dysplastic aortic valve	No	0
33	Cataract	Mild MR, ventricular septal defect	No	0
34	Bilateral cataract	MR, body asymmetry, facial hypotonia	No	0
35	Duane anomaly	Autism	No	0
36	Congenital ptosis	MR, spasticity, ataxia, unilateral deafness	No	0
37	Severe myopia	MR, dysmorphism	No	0

An = anophthalmia; Asa = anterior segment anomaly; DHPLC = denaturating high-pressure liquid chromatography; L = left; Mi = microphthalmia; MLPA = multiplex ligation-dependent probe amplification; MR = mental retardation; PHPV = persistent hyperplastic primary vitreous; R = right; RD = retinal dystrophy; RP = retinitis pigmentosa; seq = sequencing.

Agilent Array Comparative Genomic Hybridization

As starting material for the array comparative genomic hybridization experiments, 1 μg DNA was labeled with 3 μL Cy5-dCTP or Cy3-dCTP (GE Healthcare, Chalfont St. Giles, United Kingdom) and a 5-μL dNTP mix in a 50-μL reaction using the Bioprime labeling kit (Invitrogen, Carlsbad, California, USA). DNA samples from the patients and both parents were hybridized versus the same, differentially labeled normal control DNA, sex matched to the patient. After labeling, the samples were combined, and was precipitated with ethanol and resuspended in 195 μL TE buffer (Promega, Leiden, The Netherlands). The probes were prepared following the standard protocol of the producer with small modifications. The amount of Cot1 DNA was reduced to 10 μL (1 μg/μL). The 244-K slides were hybridized as recommended (Agilent Technologies, Santa Clara, California, USA). Washing of the slide was done following procedure II from the protocol provided by the producer. Briefly, the glass slides were submerged in wash buffer 1 at room temperature and were disassembled from the gasket slide. The slides were washed in series for 5 minutes in wash buffer 1 at room temperature, for 1 minute in wash buffer 2 at 37 C, for 1 minute in Acetonitrile (Sigma-Aldrich, Bornem, Belgium) at room temperature, and for 30 seconds in stabilization and drying solution (Agilent Technologies) at room temperature. The slides were dried by removing them slowly from the stabilization and drying solution. The scanning was done immediately after drying by an Agilent SureScan High-Resolution Technology (Model G2565CA) at 5-μm resolution. For the copy number changes detection and visualization, the comparative genomic hybridization analytics software (Agilent Technologies) was used. In addition, calling of aberrations was carried out using fixed thresholds for deletions (2 consecutive probes with median value lower than −0.8) and for duplications (3 consecutive probes with log2 ratio higher than 0.4). In silico simulations predicted a resolution of 30 kb for deletions and 45 kb for duplications (sensitivity, 95%). Based on log2 ratios of the probes within large imbalances, the false-negative rate was estimated at 12% for deletions and 3% for duplications. The false-positive rate was estimated to be less than 1%.

On average 60 copy number gains and losses were detected in each patient. A complete list of the deletions and duplications found in all tested patients is available in Supplementary Table 1 (available at AJO.com ). The deletions and duplications were considered potentially causal based on the following criteria: the aberration (1) occurring de novo in the patient (not present in the parents), (2) containing genes involved in the pathologic features, and (3) not overlapping with a known copy number variant.

SUPPLEMENTARY TABLE 1

List of the Deletions and Duplications Identified in the Patients with Congenital Ocular Malformations

Patient No.	CNV No.	CHR	Maximal Extent	Minimal Extent	Copy No.
1	1	1	108557062 to 108815920	108661171 to 108727836	del
1	2	1	108824934 to 108919116	108839709 to 108907080	del
1	3	1	151026228 to 151044659	151027357 to 151040463	del
1	4	1	194978218 to 195033552	195005520 to 195026703	dup
1	5	1	195045871 to 195104207	195048208 to 195091758	dup
1	6	1	246794522 to 246812523	246795223 to 246805521	amp
1	7	2	88924973 to 88971719	88932397 to 88966417	del
1	8	2	89001727 to 89056402	89009521 to 89050026	del
1	9	3	174721900 to 174785195	174736125 to 174775059	dup
1	10	4	68905670 to 69657500	69057735 to 69643272	dup
1	11	4	70207135 to 70296172	70216707 to 70264689	del
1	12	4	78963782 to 79023641	78969432 to 79011907	dup
1	13	4	79032741 to 79156090	79040612 to 79123033	dup
1	14	5	37475302 to 37515693	37491462 to 37510190	h_del
1	15	5	69274433 to 70693444	69741318 to 70622715	dup
1	16	5	180342860 to 180365950	180351118 to 180362342	del
1	17	6	32595402 to 32654432	32600962 to 32634044	dup
1	18	6	32711957 to 32738443	32718991 to 32732764	dup
1	19	6	35862502 to 35887585	35866245 to 35882448	del
1	20	6	78983276 to 79101978	79035891 to 79079988	del
1	21	7	38276237 to 38347832	38277728 to 38343026	dup
1	22	7	69932627 to 70037316	69960167 to 70018154	del
1	23	7	133414697 to 133459759	133439454 to 133447868	amp
1	24	7	141408013 to 141453012	141413352 to 141452085	del
1	25	7	141687978 to 141720324	141705163 to 141711513	amp
1	26	7	142164247 to 142182590	142167901 to 142178751	dup
1	27	7	143501811 to 143706194	143514962 to 143705425	dup
1	28	8	7701787 to 8117271	7729311 to 7789937	h_del
1	29	8	11903901 to 12511855	12077339 to 12448374	del
1	30	8	39341524 to 39535655	39356595 to 39511632	dup
1	31	8	144140391 to 144176314	144147147 to 144172829	del
1	32	9	113553851 to 113593440	113560129 to 113588082	dup
1	33	10	25040161 to 25129184	25049572 to 25085724	dup
1	34	10	89148059 to 89253592	89178988 to 89241227	del
1	35	10	96510881 to 96565677	96525911 to 96555531	dup
1	36	11	5738494 to 5777496	5742476 to 5766615	dup
1	37	11	7757329 to 7803570	7762277 to 7797993	del
1	38	11	18896166 to 18966447	18906505 to 18929375	h_del
1	39	11	55118214 to 55167475	55124730 to 55162949	del
1	40	11	55173374 to 55207305	55178955 to 55200744	del
1	41	12	10464018 to 10497371	10465787 to 10493984	dup
1	42	12	31152112 to 31248212	31162891 to 31237493	del
1	43	12	38310810 to 38368406	38327917 to 38362809	dup
1	44	12	130281182 to 130367705	130299307 to 130342639	dup
1	45	14	19397709 to 19414714	19402284 to 19408583	del
1	46	14	19420732 to 19484013	19433191 to 19479142	del
1	47	14	21635428 to 21667866	21648371 to 21662700	dup
1	48	14	21675987 to 21727722	21682650 to 21719593	dup
1	49	14	21748129 to 21791615	21759503 to 21784488	dup
1	50	14	21803299 to 21907399	21810635 to 21902353	dup
1	51	14	21920051 to 21958644	21931667 to 21951294	dup
1	52	14	21966870 to 22066142	21973343 to 22052799	dup
1	53	14	95982542 to 96014733	95987493 to 96007642	dup
1	54	14	105246206 to 105314254	105275857 to 105308045	del
1	55	14	105398979 to 105413708	105405952 to 105405952	h_del
1	56	14	105422205 to 105469325	105432521 to 105467525	del
1	57	14	105594189 to 105643293	105602756 to 105630089	h_del
1	58	14	105742795 to 105768318	105754664 to 105760541	del
1	59	14	105776293 to 105812803	105787390 to 105799261	del
1	60	14	105857193 to 105907191	105863067 to 105898674	dup
1	61	15	19397326 to 19865444	19407585 to 19860116	dup
1	62	15	19976279 to 20060061	19982333 to 20042671	dup
1	63	15	61745748 to 61778095	61752557 to 61773317	dup
1	64	17	41533641 to 41599011	41544224 to 41587723	del
1	65	17	41610132 to 41706870	41624471 to 41700762	del
1	66	17	42417429 to 42500960	42422709 to 42485131	dup
1	67	17	57470754 to 57522962	57478302 to 57513759	dup
1	68	18	41636687 to 41664464	41640210 to 41661368	dup
1	69	19	40539029 to 40562762	40543992 to 40556205	h_del
1	70	19	56816785 to 56864309	56831724 to 56859204	del
1	71	19	59487170 to 59507350	59492650 to 59502178	del
1	72	20	14277060 to 14343797	14285858 to 14335648	del
1	73	22	22681995 to 22736990	22686690 to 22731196	del
1	74	22	37689058 to 37723010	37696964 to 37718669	del
1	75	X	82658533 to 82775058	82665595 to 82744365	dup
1	76	X	91502027 to 91631974	91536773 to 91587780	dup
1	77	X	154037006 to 154050185	154050185 to 154050185	dup
2	1	1	25457903 to 25520845	25482036 to 25505750	del
2	2	1	72533856 to 72652073	72550248 to 72602597	h_del
2	3	1	110017502 to 110062339	110023268 to 110057882	dup
2	4	1	194978218 to 195045871	195005520 to 195033552	del
2	5	2	34539740 to 34627348	34556434 to 34608979	h_del
2	6	2	88924973 to 88984458	88932397 to 88971719	dup
2	7	3	163987457 to 164038917	163997228 to 164023502	del
2	8	3	164052484 to 164123806	164067241 to 164112873	del
2	9	3	174741344 to 174775059	174747656 to 174767241	del
2	10	4	70184190 to 70299545	70188454 to 70296172	dup
2	11	4	78963782 to 79023641	78969432 to 79011907	del
2	12	4	79040612 to 79203499	79049463 to 79190866	del
2	13	5	37475302 to 37510190	37491462 to 37501489	amp
2	14	5	69274433 to 70698794	69741318 to 70693444	del
2	15	6	174815 to 228968	204528 to 211079	dup
2	16	6	238441 to 284743	252939 to 273710	del
2	17	6	78983276 to 79133892	79035891 to 79101978	dup
2	18	6	165640218 to 165664947	165645537 to 165657596	h_del
2	19	7	38286537 to 38312900	38290450 to 38305379	del
2	20	7	48551463 to 48585721	48556704 to 48575004	del
2	21	11	5738494 to 5777496	5742476 to 5766615	del
2	22	11	7762277 to 7803570	7774067 to 7797993	dup
2	23	12	9452803 to 9626736	9528590 to 9613074	h_del
2	24	12	47961285 to 47977721	47964921 to 47971849	del
2	25	13	63209551 to 63305177	63230997 to 63292992	dup
2	26	14	21920051 to 21958644	21931667 to 21951294	del
2	27	14	105398979 to 105441874	105405952 to 105432521	dup
2	28	14	105594189 to 105654998	105602756 to 105643293	dup
2	29	14	105742795 to 105812803	105754664 to 105799261	dup
2	30	14	106216726 to 106268973	106223137 to 106260876	dup
2	31	15	19874690 to 19910867	19879661 to 19886840	del
2	32	16	33486907 to 33758082	33495501 to 33539023	dup
2	33	16	68679377 to 68795079	68706240 to 68754234	del
2	34	16	72937352 to 73022578	72955519 to 73012768	del
2	35	16	74095899 to 74141966	74109031 to 74132901	dup
2	36	17	41533641 to 41983407	41544224 to 41841187	dup
2	37	19	40539029 to 40556205	40543992 to 40548081	amp
2	38	20	14277060 to 14343797	14285858 to 14335648	dup
2	39	22	22681995 to 22736990	22686690 to 22731196	dup
2	40	22	37683516 to 37689058	37689058 to 37689058	dup
3	1	1	72533856 to 72652073	72550248 to 72602597	h_del
3	2	1	103899771 to 103956767	103909053 to 103932025	del
3	3	1	147213294 to 147386918	147307637 to 147357754	del
3	4	1	194978218 to 195104207	195005520 to 195091758	h_del
3	5	1	246683018 to 246750352	246688566 to 246713357	dup
3	6	1	246794522 to 246805521	246795223 to 246795223	h_del
3	7	1	246812523 to 246880850	246822838 to 246874992	h_del
3	8	2	242565932 to 242622792	242572731 to 242608960	dup
3	9	2	242637386 to 242700979	242646987 to 242689978	dup
3	10	3	163987457 to 164123806	163997228 to 164112873	dup
3	11	3	196933317 to 196968244	196942158 to 196958467	del
3	12	5	140196482 to 140228321	140203440 to 140221835	del
3	13	5	180342860 to 180379352	180351118 to 180365950	del
3	14	6	238441 to 334423	252939 to 320890	del
3	15	6	32558677 to 32634044	32567382 to 32629848	h_del
3	16	6	78983276 to 79133892	79035891 to 79101978	dup
3	17	6	165640218 to 165664947	165645537 to 165657596	h_del
3	18	7	38259147 to 38356482	38262701 to 38347832	dup
3	19	7	84007547 to 84166944	84037987 to 84131752	del
3	20	7	141408013 to 141453012	141413352 to 141452085	dup
3	21	7	142036600 to 142087282	142045309 to 142076928	dup
3	22	7	143514962 to 143706194	143582864 to 143705425	dup
3	23	8	39341524 to 39535655	39356595 to 39511632	h_del
3	24	9	11971564 to 12153230	11997047 to 12137751	del
3	25	9	39146895 to 40622401	39157302 to 40498765	dup
3	26	9	43165653 to 44263920	43445839 to 44199401	dup
3	27	9	93715398 to 93747859	93721400 to 93742534	dup
3	28	9	112060652 to 112086263	112064860 to 112074405	del
3	29	11	5738494 to 5777496	5742476 to 5766615	dup
3	30	11	55118214 to 55207305	55124730 to 55200744	dup
3	31	12	7884886 to 7963159	7894681 to 7956956	dup
3	32	12	7969578 to 8056718	7979868 to 8036400	dup
3	33	12	10457163 to 10497371	10464018 to 10493984	dup
3	34	14	20418299 to 20490129	20423918 to 20481680	del
3	35	14	21667866 to 21727722	21675987 to 21719593	dup
3	36	14	21734331 to 21791615	21739283 to 21784488	dup
3	37	14	21803299 to 21896334	21810635 to 21881623	dup
3	38	14	21902353 to 22046097	21907399 to 22034704	dup
3	39	14	26230274 to 26527516	26243812 to 26508448	del
3	40	14	105398979 to 105432521	105405952 to 105422205	del
3	41	14	105536949 to 105584008	105545545 to 105576121	del
3	42	14	105845658 to 105907191	105857193 to 105898674	dup
3	43	15	19786655 to 19952195	19805960 to 19943194	dup
3	44	16	2605126 to 2645485	2638581 to 2638643	amp
3	45	16	18205105 to 18687416	18214307 to 18599499	dup
3	46	16	21854083 to 22625780	21858880 to 22553207	dup
3	47	16	32208242 to 32745412	32378126 to 32561819	dup
3	48	16	68710277 to 68754234	68726557 to 68751390	del
3	49	19	59487170 to 59507350	59492650 to 59502178	del
3	50	21	43637814 to 43669640	43649217 to 43666311	dup
3	51	22	22681995 to 22731196	22686690 to 22725305	del
3	52	22	37683516 to 37723010	37689058 to 37718669	dup
3	53	X	62321946 to 62453817	62390645 to 62434259	del
3	54	X	154192848 to 154209875	154209875 to 154209875	del
4	1	1	554268 to 736483	554287 to 639581
4	2	1	17088704 to 17157415	17094475 to 17148592	dup
4	3	1	25457903 to 25541997	25482036 to 25536086	h_del
4	4	1	71762077 to 71800558	71772149 to 71794284	dup
4	5	1	147213294 to 147421614	147307637 to 147386918	dup
4	6	1	151026228 to 151044659	151027357 to 151040463	dup
4	7	2	34539740 to 34627348	34556434 to 34608979	del
4	8	3	32252318 to 32455878	32263152 to 32444367	del
4	9	3	32471286 to 33866803	32476955 to 33858308	del
4	10	3	33873495 to 34208163	33884066 to 34178961	del
4	11	3	47199722 to 47251350	47209546 to 47244906	dup
4	12	3	75845446 to 75914406	75858339 to 75896020	dup
4	13	3	164023502 to 164123806	164038917 to 164112873	dup
4	14	4	61943580 to 62609120	61954159 to 62592698	del
4	15	4	69057735 to 69097336	69069563 to 69085386	del
4	16	4	69114068 to 69657500	69120805 to 69643272	del
4	17	5	104440605 to 104543503	104473613 to 104501153	amp
4	18	5	140196482 to 140228321	140203440 to 140221835	del
4	19	5	180194323 to 180379352	180342860 to 180365950	del
4	20	6	29950805 to 30021894	29962849 to 30010234	del
4	21	7	17083302 to 17189295	17110906 to 17155158	del
4	22	7	38259147 to 38356482	38262701 to 38347832	dup
4	23	7	141402937 to 141453012	141408013 to 141452085	dup
4	24	7	142141101 to 142207147	142152205 to 142202274	dup
4	25	7	143514962 to 143706194	143582864 to 143705425	dup
4	26	8	39341524 to 39535655	39356595 to 39511632	del
4	27	11	5738494 to 5777496	5742476 to 5766615	dup
4	28	11	55118214 to 55207305	55124730 to 55200744	h_del
4	29	12	51545224 to 51590986	51553835 to 51584137	dup
4	30	14	19216369 to 19505698	19268776 to 19497023	del
4	31	14	21863320 to 21907399	21868942 to 21902353	dup
4	32	14	21920051 to 22052799	21931667 to 22046097	dup
4	33	14	40670538 to 40779816	40704122 to 40746865	del
4	34	14	69078818 to 69106345	69088190 to 69098569	del
4	35	14	105602756 to 105654998	105609466 to 105643293	del
4	36	14	105857193 to 105898674	105863067 to 105881279	del
4	37	14	106216726 to 106260876	106223137 to 106251081	del
4	38	15	18810004 to 19130748	18835660 to 19121757	del
4	39	15	19137963 to 19215427	19146596 to 19206779	del
4	40	15	19371946 to 19418600	19382527 to 19407585	del
4	41	15	19537035 to 19874690	19786655 to 19869705	del
4	42	15	19879661 to 19943194	19882711 to 19933992	del
4	43	15	19963175 to 20042671	19970687 to 20010559	del
4	44	15	22163893 to 22329016	22232458 to 22289273	dup
4	45	15	36977859 to 37131655	37000216 to 37123890	dup
4	46	16	2592859 to 2662050	2605126 to 2649851	dup
4	47	16	21854083 to 22625780	21858880 to 22553207	dup
4	48	16	32004586 to 32748349	32105104 to 32745412	dup
4	49	17	19433346 to 19495498	19445241 to 19486672	del
4	50	22	37683516 to 37723010	37689058 to 37718669	h_del
4	51	22	41226636 to 41248173	41237731 to 41241786	dup
4	52	22	41254513 to 41291691	41260534 to 41287060	dup
4	53	X	62321946 to 62453817	62390645 to 62434259	del
4	54	X	153127027 to 153176364	153158679 to 153158822	amp
4	55	X	154192848 to 154209875	154209875 to 154209875	del
5	1	1	1760470 to 1796982	1770119 to 1790106	del
5	2	1	246794522 to 246822838	246795223 to 246812523	h_del
5	3	2	88924973 to 89050026	88932397 to 89040625	dup
5	4	2	89056402 to 89207763	89078609 to 89145587	dup
5	5	2	227946001 to 227990692	227952131 to 227973265	dup
5	6	3	89473678 to 89516057	89488409 to 89509246	del
5	7	3	174741344 to 174785195	174747656 to 174775059	del
5	8	4	70207135 to 70296172	70216707 to 70264689	dup
5	9	4	78963782 to 79004213	78969432 to 78995025	del
5	10	5	22017081 to 22069078	22022635 to 22056803	del
5	11	5	69274433 to 70716278	69741318 to 70698794	del
5	12	5	150166447 to 150224239	150185190 to 150209789	del
5	13	5	168963841 to 169002159	168964326 to 168988751	del
5	14	6	174815 to 252939	204528 to 238441	dup
5	15	6	29950805 to 30021894	29962849 to 30010234	del
5	16	6	32711957 to 32738443	32718991 to 32732764	del
5	17	6	78983276 to 79133892	79035891 to 79101978	dup
5	18	7	8667450 to 8712044	8684008 to 8705274	del
5	19	7	141408013 to 141453012	141413352 to 141452085	dup
5	20	7	142164247 to 142178751	142167901 to 142178220	h_del
5	21	8	39363050 to 39441842	39368509 to 39435320	del
5	22	8	39449624 to 39535655	39457650 to 39511632	del
5	23	11	7757329 to 7803570	7762277 to 7797993	dup
5	24	11	55118214 to 55207305	55124730 to 55200744	dup
5	25	11	110843459 to 110878874	110853364 to 110872980	del
5	26	13	56650373 to 56726008	56658479 to 56691355	del
5	27	14	69078818 to 69106345	69088190 to 69098569	h_del
5	28	14	73060301 to 73106558	73071404 to 73104572	del
5	29	14	105398979 to 105467525	105405952 to 105461412	dup
5	30	14	105469325 to 105524683	105476748 to 105515561	dup
5	31	14	105536949 to 105584008	105545545 to 105576121	dup
5	32	14	105594189 to 105643293	105602756 to 105630089	dup
5	33	14	105794161 to 105823416	105799261 to 105818290	del
5	34	14	105845658 to 105907191	105857193 to 105898674	del
5	35	15	18790589 to 18874663	18810004 to 18864582	dup
5	36	15	18884436 to 19227549	19109124 to 19215427	dup
5	37	15	19235401 to 19338183	19253730 to 19321280	dup
5	38	15	19347444 to 19407585	19355643 to 19397326	dup
5	39	15	19418600 to 19786655	19427350 to 19537035	dup
5	40	15	19819961 to 19865444	19833542 to 19860116	dup
5	41	15	19869705 to 19952195	19874690 to 19943194	dup
5	42	15	19963175 to 20010559	19970687 to 19988304	dup
5	43	17	41515622 to 41983407	41521544 to 41841187	dup
5	44	19	40539029 to 40556205	40543992 to 40548081	amp
5	45	19	58663140 to 58747326	58675423 to 58731596	dup
5	46	20	14277060 to 14343797	14285858 to 14335648	dup
5	47	22	22671374 to 22736990	22677959 to 22731196	dup
5	48	22	37683516 to 37723010	37689058 to 37718669	dup
5	49	22	41368840 to 41472324	41374682 to 41453594	dup
5	50	X	91688147 to 91712654	91712654 to 91712654	del
6	1	1	25457903 to 25547799	25482036 to 25541997	dup
6	2	1	72533856 to 72602597	72550248 to 72568009	amp
6	3	1	110017502 to 110062339	110023268 to 110057882	del
6	4	1	116950996 to 117008723	116970390 to 117001475	dup
6	5	1	147213294 to 147357754	147307637 to 147329819	amp
6	6	1	147386918 to 147927292	147421614 to 147499046	dup
6	7	1	159746016 to 159768406	159749609 to 159767602	dup
6	8	1	159786265 to 159917038	159791446 to 159913146	dup
6	9	1	246812523 to 246880850	246822838 to 246874992	dup
6	10	2	32531218 to 32652426	32543371 to 32640703	del
6	11	2	32697011 to 32822023	32704772 to 32812404	del
6	12	2	32831262 to 32878011	32836817 to 32871072	del
6	13	2	32907228 to 33062778	32916239 to 33054999	del
6	14	2	33071907 to 33121271	33080437 to 33110959	del
6	15	2	33156634 to 33189314	33167797 to 33178884	del
6	16	2	34539740 to 34608979	34556434 to 34580533	amp
6	17	2	87229588 to 87661927	87552703 to 87613207	dup
6	18	2	88910647 to 89145587	88924973 to 89104501	dup
6	19	2	89669494 to 89755931	89731561 to 89750144	del
6	20	2	89856321 to 90982930	89863711 to 89895566	del
6	21	2	111721172 to 111952139	111843508 to 111932907	dup
6	22	2	132130850 to 132210342	132152891 to 132206366	dup
6	23	3	152985586 to 153042650	152996121 to 153035523	del
6	24	3	174721900 to 174775059	174736125 to 174767241	del
6	25	3	187882442 to 187912641	187891716 to 187905544	del
6	26	4	68905670 to 69657500	69057735 to 69643272	del
6	27	5	745859 to 826044	763494 to 819038	del
6	28	5	837253 to 905462	848744 to 894957	del
6	29	5	37475302 to 37510190	37491462 to 37501489	amp
6	30	5	140196482 to 140228321	140203440 to 140221835	del
6	31	5	175537148 to 175657218	175563657 to 175648882	dup
6	32	5	180194323 to 180379352	180342860 to 180365950	dup
6	33	6	174815 to 262620	204528 to 252939	dup
6	34	6	273710 to 334423	284743 to 320890	dup
6	35	6	32507380 to 32629848	32519935 to 32605300	dup
6	36	6	78983276 to 79133892	79035891 to 79101978	del
6	37	7	38259147 to 38343026	38262701 to 38335964	del
6	38	7	133414697 to 133465974	133439454 to 133459759	h_del
6	39	7	141408013 to 141453012	141413352 to 141452085	dup
6	40	7	141687978 to 141720324	141705163 to 141711513	amp
6	41	8	7040596 to 7701787	7256229 to 7359040	del
6	42	8	39341524 to 39535655	39356595 to 39511632	h_del
6	43	9	112060652 to 112086263	112064860 to 112074405	del
6	44	11	5738494 to 5777496	5742476 to 5766615	dup
6	45	11	55118214 to 55207305	55124730 to 55200744	dup
6	46	12	9452803 to 9626736	9528590 to 9613074	del
6	47	14	18504575 to 18864561	18537177 to 18642252	dup
6	48	14	19090564 to 19505698	19154992 to 19497023	dup
6	49	14	21624686 to 21662700	21635428 to 21654727	del
6	50	14	21688696 to 21734331	21698018 to 21727722	del
6	51	14	21739283 to 21766804	21748129 to 21759503	del
6	52	14	21771961 to 21907399	21784488 to 21902353	del
6	53	14	21920051 to 22046097	21931667 to 22034704	del
6	54	14	40670538 to 40779816	40704122 to 40746865	h_del
6	55	14	73060301 to 73106558	73071404 to 73104572	dup
6	56	14	105314254 to 105384766	105322191 to 105379293	dup
6	57	14	105398979 to 105467525	105405952 to 105461412	dup
6	58	14	105469325 to 105863067	105476748 to 105857193	dup
6	59	15	19146596 to 19215427	19162213 to 19206779	dup
6	60	15	19227549 to 19338183	19235401 to 19321280	dup
6	61	15	19347444 to 19427350	19355643 to 19418600	dup
6	62	15	19865444 to 19927262	19869705 to 19910867	dup
6	63	16	613201 to 647355	621556 to 640261	dup
6	64	16	21476688 to 21507188	21482409 to 21501073	del
6	65	16	31862577 to 32745412	31958973 to 32561819	dup
6	66	16	32748349 to 33875313	33205648 to 33758082	dup
6	67	17	31456645 to 31889297	31461588 to 31504564	del
6	68	17	41515622 to 41553226	41521544 to 41544224	dup
6	69	17	41558893 to 41706870	41566540 to 41700762	dup
6	70	18	65342290 to 65375155	65359770 to 65367911	amp
6	71	19	56816785 to 56850433	56831724 to 56840346	amp
6	72	21	46914686 to 15019428	14504218 to 14884298	dup
6	73	22	21292941 to 21353650	21328284 to 21346750	dup
6	74	22	22671374 to 22736990	22677959 to 22731196	dup
6	75	X	62321946 to 62390645	62390645 to 62390645	h_del
7	1	1	103956767 to 104109172	103965227 to 104108153	del
7	2	1	146375659 to 148081741	147134175 to 148035420	dup
7	3	1	151026228 to 151044659	151027357 to 151040463	del
7	4	1	16964267 to 17094475	17082119 to 17088704	dup
7	5	1	17104345 to 17157415	17114337 to 17148592	dup
7	6	1	194978218 to 195033552	195005520 to 195026703	del
7	7	1	195045871 to 195091758	195048208 to 195067764	del
7	8	1	25457903 to 25547799	25482036 to 25541997	dup
7	9	11	368197 to 400035	373890 to 393800	dup
7	10	11	55118214 to 55207305	55124730 to 55200744	dup
7	11	11	5738494 to 5777496	5742476 to 5766615	dup
7	12	12	11393473 to 11444721	11404653 to 11430887	del
7	13	12	132174410 to 132205268	132188959 to 132199350	dup
7	14	12	132217362 to 132278000	132223020 to 132273962	dup
7	15	12	9452803 to 9613074	9528590 to 9585156	del
7	16	14	105280523 to 105330913	105286479 to 105322191	dup
7	17	14	105343150 to 105391340	105349928 to 105384766	dup
7	18	14	105398979 to 105584008	105405952 to 105576121	dup
7	19	14	105594189 to 105654998	105602756 to 105643293	h_del
7	20	14	105693581 to 105787390	105701420 to 105776293	dup
7	21	14	105799261 to 105873009	105812803 to 105863067	dup
7	22	14	105923159 to 105985458	105934843 to 105977946	dup
7	23	14	106216726 to 106268973	106223137 to 106260876	dup
7	24	15	19819961 to 19952195	19833542 to 19943194	dup
7	25	15	19963175 to 20042671	19970687 to 20010559	dup
7	26	16	21444431 to 21521005	21448093 to 21507188	del
7	27	16	2605126 to 2649851	2638581 to 2645485	del
7	28	16	87042455 to 87082395	87054341 to 87071660	del
7	29	17	31456645 to 31889297	31461588 to 31504564	del
7	30	17	41515622 to 41553226	41521544 to 41544224	dup
7	31	17	41558893 to 41706870	41566540 to 41700762	dup
7	32	17	77503378 to 77535412	77503673 to 77519913	del
7	33	18	65342290 to 65375155	65359770 to 65367911	amp
7	34	19	20463727 to 20523656	20474417 to 20510787	del
7	35	19	56816785 to 56850433	56831724 to 56840346	amp
7	36	2	32480016 to 32548723	32496047 to 32543371	del
7	37	2	32557276 to 32640703	32564277 to 32628022	del
7	38	2	32652426 to 32686168	32659456 to 32676340	del
7	39	2	32696811 to 32781516	32697011 to 32772603	del
7	40	2	32790864 to 32891109	32799455 to 32878011	del
7	41	2	32907228 to 33017315	32916239 to 33008263	del
7	42	2	33030410 to 33062778	33041064 to 33054999	del
7	43	2	33071907 to 33102581	33080437 to 33093716	del
7	44	2	33110959 to 33148227	33121271 to 33139801	del
7	45	2	38801777 to 38835011	38810280 to 38829605	dup
7	46	2	87178812 to 87786474	87229588 to 87781651	dup
7	47	2	88924973 to 89256456	88932397 to 89220538	dup
7	48	22	21506376 to 21568861	21513732 to 21558810	dup
7	49	22	22644243 to 22731196	22656831 to 22725305	dup
7	50	22	46095419 to 46271999	46108854 to 46263970	del
7	51	X	62321946 to 62453817	62390645 to 62434259	h_del
7	52	3	164023502 to 164123806	164038917 to 164112873	h_del
7	53	3	187882442 to 187912641	187891716 to 187905544	del
7	54	3	196656498 to 196929805	196904349 to 196924340	dup
7	55	3	89473678 to 89509246	89488409 to 89499433	del
7	56	5	180194323 to 180379352	180342860 to 180365950	dup
7	57	5	37475302 to 37510190	37491462 to 37501489	amp
7	58	5	745859 to 826044	763494 to 819038	del
7	59	5	837253 to 905462	848744 to 894957	del
7	60	6	165640218 to 165664947	165645537 to 165657596	del
7	61	6	29975388 to 30021894	29981930 to 30010234	dup
7	62	7	141408013 to 141453012	141413352 to 141452085	dup
7	63	7	141687978 to 141720324	141705163 to 141711513	amp
7	64	7	142152205 to 142178751	142159154 to 142178220	dup
7	65	7	143514962 to 143705425	143582864 to 143584350	del
7	66	8	39341524 to 39535655	39356595 to 39511632	h_del
7	67	9	112060652 to 112086263	112064860 to 112074405	del
7	68	9	5289937 to 5298149	5298149 to 5298149	del
8	1	1	12762774 to 12840011	12776479 to 12835156	dup
8	2	1	16964267 to 17157415	17082119 to 17148592	dup
8	3	1	72533856 to 72652073	72550248 to 72602597	h_del
8	4	1	147213294 to 147946905	147307637 to 147927292	h_del
8	5	1	150819451 to 150857070	150823073 to 150852858	del
8	6	1	151026228 to 151044659	151027357 to 151040463	dup
8	7	1	159758730 to 159791446	159762714 to 159786265	dup
8	8	1	246683018 to 246750352	246688566 to 246713357	dup
8	9	1	246794522 to 246805521	246795223 to 246795223	del
8	10	1	246812523 to 246880850	246822838 to 246874992	h_del
8	11	2	89408826 to 89755931	89654638 to 89750144	del
8	12	2	89856321 to 90982930	89863711 to 89895566	del
8	13	3	75799957 to 75914406	75845446 to 75896020	dup
8	14	3	163987457 to 164123806	163997228 to 164112873	dup
8	15	3	196656498 to 196942158	196904349 to 196933317	del
8	16	5	786455 to 826044	802518 to 819038	del
8	17	5	837253 to 905462	848744 to 894957	del
8	18	5	180194323 to 180379352	180342860 to 180365950	dup
8	19	6	32519935 to 32595402	32558677 to 32586131	h_del
8	20	6	32600962 to 32634044	32605300 to 32629848	amp
8	21	6	78983276 to 79133892	79035891 to 79101978	h_del
8	22	7	100162851 to 100194979	100171204 to 100183859	h_del
8	23	7	128766157 to 128801493	128775509 to 128789921	del
8	24	7	141687978 to 141727147	141705163 to 141720324	h_del
8	25	7	143514962 to 143706194	143582864 to 143705425	del
8	26	8	12077339 to 12548003	12276178 to 12511855	dup
8	27	8	39341524 to 39535655	39356595 to 39511632	dup
8	28	12	7884886 to 7956956	7894681 to 7944668	dup
8	29	12	7963159 to 8036400	7969578 to 8009244	dup
8	30	12	9452803 to 9626736	9528590 to 9613074	h_del
8	31	12	10464018 to 10497371	10465787 to 10493984	del
8	32	13	42629858 to 42696134	42663797 to 42691461	dup
8	33	14	19284254 to 19350230	19293976 to 19330937	dup
8	34	14	19408583 to 19505698	19414714 to 19497023	dup
8	35	14	73060301 to 73106558	73071404 to 73104572	dup
8	36	14	106216726 to 106268973	106223137 to 106260876	del
8	37	15	18810004 to 18874663	18835660 to 18864582	del
8	38	15	19874690 to 19910867	19879661 to 19886840	del
8	39	16	28516947 to 28542215	28523145 to 28536745	del
8	40	17	41515622 to 41983407	41521544 to 41841187	dup
8	41	19	40539029 to 40556205	40543992 to 40548081	amp
8	42	19	59487170 to 59507350	59492650 to 59502178	del
8	43	22	22644243 to 22658543	22656831 to 22656831	del
8	44	22	22671374 to 22736990	22677959 to 22731196	dup
8	45	22	33086125 to 33291150	33121333 to 33242946	del
8	46	X	115479732 to 115655322	115487962 to 115617407	del
8	47	X	153127027 to 153158679	153158679 to 153158679	del
9	1	1	17094475 to 17148592	17104345 to 17130528	del
9	2	1	150819451 to 150861724	150823073 to 150857070	del
9	3	1	151026228 to 151044659	151027357 to 151040463	dup
9	4	1	167483267 to 167538962	167493768 to 167523140	del
9	5	1	194978218 to 195104207	195005520 to 195091758	h_del
9	6	1	246755225 to 246805521	246794522 to 246795223	h_del
9	7	1	246812523 to 246890704	246822838 to 246880850	h_del
9	8	2	187714155 to 187888176	187758371 to 187867949	dup
9	9	2	227946001 to 227990692	227952131 to 227973265	dup
9	10	3	163987457 to 164123806	163997228 to 164112873	dup
9	11	3	174721900 to 174785195	174736125 to 174775059	dup
9	12	4	68905670 to 69657500	69057735 to 69643272	dup
9	13	5	32133136 to 32217543	32146491 to 32209048	h_del
9	14	5	180194323 to 180379352	180342860 to 180365950	dup
9	15	6	32519935 to 32595402	32558677 to 32586131	del
9	16	6	32718991 to 32738443	32723366 to 32732764	del
9	17	6	78983276 to 79133892	79035891 to 79101978	dup
9	18	6	124466262 to 124531059	124478216 to 124521619	dup
9	19	6	165640218 to 165672790	165645537 to 165664947	dup
9	20	7	141408013 to 141453012	141413352 to 141452085	dup
9	21	7	141687978 to 141727147	141705163 to 141720324	del
9	22	7	142152205 to 142178751	142159154 to 142178220	del
9	23	7	143514962 to 143706194	143582864 to 143705425	del
9	24	8	7040596 to 7701787	7256229 to 7359040	del
9	25	8	39341524 to 39535655	39356595 to 39511632	del
9	26	9	17568661 to 17626610	17585185 to 17620872	del
9	27	9	116113464 to 116138267	116122595 to 116132839	del
9	28	9	139345200 to 139382135	139360238 to 139373555	del
9	29	12	9452803 to 9633884	9528590 to 9626736	dup
9	30	12	10464018 to 10497371	10465787 to 10493984	del
9	31	12	21224163 to 21313078	21241119 to 21295374	dup
9	32	14	19216369 to 19505698	19268776 to 19497023	del
9	33	14	105594189 to 105654998	105602756 to 105643293	del
9	34	14	105946993 to 106002179	105962305 to 105994646	dup
9	35	15	19865444 to 19927262	19869705 to 19910867	del
9	36	16	2592859 to 2649851	2605126 to 2645485	dup
9	37	16	34297461 to 34685270	34339543 to 34634686	dup
9	38	17	41515622 to 41706870	41521544 to 41700762	dup
9	39	19	20617303 to 20681272	20621912 to 20660195	dup
9	40	19	20691665 to 20810051	20701795 to 20792989	dup
9	41	21	9931866 to 10013263	9936926 to 10007253	dup
9	42	21	43637814 to 43669640	43649217 to 43666311	dup
9	43	22	22681995 to 22731196	22686690 to 22725305	del
9	44	22	23984069 to 24039445	23994618 to 24032133	del
9	45	22	24047238 to 24077248	24056350 to 24065351	del
9	46	22	24082742 to 24098454	24087722 to 24090907	del
9	47	22	24104708 to 24149074	24112813 to 24129523	del
9	48	22	24161684 to 24177012	24170487 to 24170487	del
9	49	22	24181763 to 24268562	24187585 to 24254026	del
9	50	22	37683516 to 37723010	37689058 to 37718669	dup
9	51	22	41226636 to 41237731	41237731 to 41237731	dup
10	1	1	947337 to 998149	954560 to 982634	del
10	2	1	1065951 to 1087142	1070587 to 1079186	del
10	3	1	7478363 to 7508072	7484428 to 7501743	del
10	4	1	17104345 to 17157415	17114337 to 17148592	dup
10	5	1	25505750 to 25547799	25520845 to 25541997	dup
10	6	1	108701727 to 108839709	108727836 to 108824934	del
10	7	1	110033832 to 110068307	110041428 to 110062339	del
10	8	1	116950996 to 117008723	116970390 to 117001475	dup
10	9	1	147134175 to 147357754	147203277 to 147329819	dup
10	10	1	147386918 to 147438471	147421614 to 147421614	amp
10	11	1	147458669 to 147965985	147475854 to 147946905	dup
10	12	1	150839754 to 150861724	150844444 to 150857070	dup
10	13	1	151851896 to 151871208	151854424 to 151865360	del
10	14	1	159746016 to 159767602	159749609 to 159762714	dup
10	15	1	159768406 to 159885469	159772583 to 159876777	dup
10	16	1	159890857 to 159917038	159895967 to 159913146	dup
10	17	1	194978218 to 195033552	195005520 to 195026703	del
10	18	1	195045871 to 195091758	195048208 to 195067764	del
10	19	1	246812523 to 246890704	246822838 to 246880850	dup
10	20	2	32704772 to 32781516	32712425 to 32772603	del
10	21	2	32916239 to 33030410	32927818 to 33017315	del
10	22	2	33110959 to 33156634	33121271 to 33148227	del
10	23	2	87178812 to 87661927	87229588 to 87613207	dup
10	24	2	88984458 to 89009521	88995175 to 89001727	del
10	25	2	89015715 to 89093646	89025329 to 89078609	del
10	26	2	91167361 to 91435969	91176207 to 91391623	dup
10	27	3	129858677 to 129919473	129872915 to 129903593	del
10	28	3	163987457 to 164123806	163997228 to 164112873	dup
10	29	3	174721900 to 174775059	174736125 to 174767241	del
10	30	3	196656498 to 196945209	196904349 to 196943380	dup
10	31	4	68905670 to 69114068	69057735 to 69097336	del
10	32	4	69120805 to 69657500	69139037 to 69643272	del
10	33	4	70201666 to 70255674	70207135 to 70237778	del
10	34	5	150166447 to 150224239	150185190 to 150209789	del
10	35	6	174815 to 262620	204528 to 252939	dup
10	36	6	32519935 to 32654432	32558677 to 32634044	dup
10	37	6	33357305 to 33373305	33360021 to 33367581	del
10	38	6	49681461 to 49712305	49686767 to 49700784	del
10	39	6	165640218 to 165664947	165645537 to 165657596	h_del
10	40	7	73625048 to 73654773	73632170 to 73645466	del
10	41	7	142152205 to 142178751	142159154 to 142178220	dup
10	42	8	6929691 to 8132139	7040596 to 8117271	dup
10	43	8	11903901 to 12548003	12077339 to 12511855	dup
10	44	8	137737806 to 137970939	137762418 to 137952089	del
10	45	8	144766559 to 144797852	144771419 to 144792138	del
10	46	9	110660322 to 110676976	110664379 to 110669955	del
10	47	9	139367214 to 139398990	139373555 to 139390002	del
10	48	10	46396163 to 46427571	46404919 to 46423080	dup
10	49	11	498057 to 528459	505016 to 522228	del
10	50	11	1143723 to 1169752	1146926 to 1152195	del
10	51	11	5742476 to 5777496	5749258 to 5766615	dup
10	52	11	7741548 to 7908934	7750215 to 7904937	del
10	53	11	55118214 to 55207305	55124730 to 55200744	dup
10	54	11	61267060 to 61306225	61273416 to 61294993	del
10	55	11	89344807 to 89482692	89400624 to 89470943	dup
10	56	12	9452803 to 9626736	9528590 to 9613074	h_del
10	57	14	19154992 to 19505698	19216369 to 19497023	dup
10	58	14	105398979 to 105441874	105405952 to 105432521	h_del
10	59	14	105447369 to 105504747	105455799 to 105481933	del
10	60	14	105536949 to 105609466	105545545 to 105602756	del
10	61	14	105857193 to 105923159	105863067 to 105907191	dup
10	62	14	105946993 to 105994646	105962305 to 105985458	dup
10	63	15	19819961 to 19970687	19833542 to 19963175	dup
10	64	15	70750307 to 70781787	70755408 to 70774534	del
10	65	15	74781214 to 74810284	74794160 to 74804475	del
10	66	15	95606006 to 95668297	95616750 to 95658438	del
10	67	16	768304 to 785690	772310 to 781667	del
10	68	16	2958313 to 2972337	2960642 to 2967124	del
10	69	16	21476688 to 21521005	21482409 to 21507188	del
10	70	16	32378126 to 32561819	32481309 to 32553402	dup
10	71	16	33486907 to 33875313	33495501 to 33758082	dup
10	72	16	34397154 to 34605030	34422716 to 34584793	dup
10	73	16	54354643 to 54390012	54359983 to 54379834	del
10	74	16	68706240 to 68838368	68710277 to 68795079	del
10	75	16	72917554 to 73022578	72933295 to 73012768	del
10	76	17	18076999 to 18097947	18081225 to 18094168	del
10	77	17	31456645 to 31889297	31461588 to 31504564	del
10	78	17	40859120 to 40901702	40866689 to 40875298	del
10	79	17	41566540 to 41624471	41577520 to 41610132	dup
10	80	17	74172980 to 74209389	74181930 to 74199543	del
10	81	18	65342290 to 65375155	65359770 to 65367911	amp
10	82	19	5729696 to 5752521	5735403 to 5746580	del
10	83	19	9854941 to 9892231	9861570 to 9884898	del
10	84	19	36476428 to 36524581	36493923 to 36515039	del
10	85	19	54931361 to 54963635	54942158 to 54956276	del
10	86	19	56816785 to 56850433	56831724 to 56840346	amp
10	87	19	58538365 to 58581834	58545115 to 58574652	del
10	88	20	1506379 to 1546858	1516966 to 1539155	del
10	89	20	2982557 to 3007090	2987877 to 3001121	del
10	90	20	61657232 to 61678601	61659922 to 61669839	del
10	91	22	17343306 to 17409602	17348891 to 17403824	dup
10	92	22	22681995 to 22731196	22686690 to 22725305	dup
10	93	22	24077248 to 24104708	24082742 to 24098454	del
10	94	X	52909690 to 52971245	52916249 to 52966148	del
10	95	X	62321946 to 62453817	62390645 to 62434259	h_del
10	96	X	152676750 to 152691296	152680934 to 152688197	del
10	97	X	153067477 to 153186834	153127027 to 153176364	dup
10	98	X	153266347 to 153278927	153278927 to 153278927	del
11	1	1	110017502 to 110062339	110023268 to 110057882	dup
11	2	1	150819451 to 150861724	150823073 to 150857070	dup
11	3	2	88932397 to 88984458	88944977 to 88971719	dup
11	4	3	174741344 to 174775059	174747656 to 174767241	del
11	5	3	187882442 to 187912641	187891716 to 187905544	del
11	6	4	3314415 to 3348996	3325525 to 3341510	del
11	7	4	70130975 to 70299545	70159690 to 70296172	dup
11	8	4	78963782 to 79032741	78969432 to 79023641	del
11	9	4	79040612 to 79123033	79049463 to 79106315	del
11	10	5	19032752 to 19161188	19057977 to 19124080	del
11	11	5	37475302 to 37510190	37491462 to 37501489	amp
11	12	5	69274433 to 70422297	69741318 to 70345552	h_del
11	13	5	180342860 to 180379352	180351118 to 180365950	dup
11	14	6	10569605 to 10645400	10580427 to 10637180	del
11	15	6	29950805 to 30021894	29962849 to 30010234	del
11	16	6	78983276 to 79133892	79035891 to 79101978	dup
11	17	6	165640218 to 165664947	165645537 to 165657596	del
11	18	7	141408013 to 141453012	141413352 to 141452085	dup
11	19	7	143514962 to 143706194	143582864 to 143705425	dup
11	20	8	7261418 to 7789937	7359040 to 7747772	dup
11	21	8	12077339 to 12448374	12276178 to 12285464	amp
11	22	8	39363050 to 39441842	39368509 to 39435320	del
11	23	8	39449624 to 39535655	39457650 to 39511632	del
11	24	10	27660038 to 27674090	27667466 to 27667466	h_del
11	25	10	27684676 to 27712190	27697186 to 27697186	del
11	26	10	27717951 to 27791782	27727513 to 27761657	del
11	27	11	7762277 to 7803570	7774067 to 7797993	dup
11	28	11	101517662 to 101569662	101529178 to 101564145	del
11	29	12	9452803 to 9626736	9528590 to 9613074	dup
11	30	12	10465787 to 10497371	10474925 to 10493984	del
11	31	12	47961285 to 47977721	47964921 to 47971849	del
11	32	14	19268776 to 19323579	19273289 to 19317571	dup
11	33	14	19380994 to 19505698	19388122 to 19497023	dup
11	34	14	73071404 to 73104572	73075500 to 73092018	del
11	35	14	105398979 to 105441874	105405952 to 105432521	dup
11	36	14	105594189 to 105643293	105602756 to 105630089	dup
11	37	14	105708209 to 105768318	105724107 to 105760541	dup
11	38	14	105776293 to 105823416	105787390 to 105818290	dup
11	39	15	19435500 to 19805960	19465359 to 19786655	del
11	40	15	19869705 to 19910867	19874690 to 19886840	dup
11	41	15	22055553 to 22364310	22077517 to 22346355	dup
11	42	17	41515622 to 41983407	41521544 to 41841187	dup
11	43	19	40539029 to 40556205	40543992 to 40548081	amp
11	44	20	14277060 to 14343797	14285858 to 14335648	dup
11	45	22	37683516 to 37689058	37689058 to 37689058	dup
12	1	1	17094475 to 17148592	17104345 to 17130528	dup
12	2	1	72533856 to 72602597	72550248 to 72568009	amp
12	3	1	103899771 to 104108153	103909053 to 103965274	dup
12	4	1	150819451 to 150861724	150823073 to 150857070	h_del
12	5	1	151026228 to 151044659	151027357 to 151040463	dup
12	6	1	167483267 to 167523140	167493768 to 167507882	amp
12	7	1	246812523 to 246880850	246822838 to 246874992	dup
12	8	2	38801777 to 38829605	38810280 to 38821814	del
12	9	2	56441398 to 56599636	56450845 to 56540016	del
12	10	2	88910647 to 88995175	88924973 to 88984458	dup
12	11	2	89001727 to 89050026	89009521 to 89040625	dup
12	12	2	89669494 to 90982930	89731561 to 89895566	del
12	13	3	164023502 to 164123806	164038917 to 164112873	dup
12	14	3	196656498 to 196943380	196904349 to 196942158	del
12	15	4	6714827 to 6743704	6721420 to 6736858	del
12	16	4	68905670 to 69114068	69057735 to 69097336	del
12	17	4	69120805 to 69657500	69139037 to 69643272	del
12	18	4	70130975 to 70299545	70159690 to 70296172	dup
12	19	5	37475302 to 37510190	37491462 to 37501489	amp
12	20	5	69274433 to 70345552	69741318 to 70343857	del
12	21	5	175563657 to 175648882	175590732 to 175600582	amp
12	22	6	238441 to 341386	252939 to 334423	del
12	23	6	29950805 to 30021894	29962849 to 30010234	del
12	24	6	32711957 to 32732764	32718991 to 32728487	del
12	25	7	66125189 to 66153026	66131707 to 66145748	amp
12	26	7	133414697 to 133465974	133439454 to 133459759	h_del
12	27	7	142152205 to 142178751	142159154 to 142178220	del
12	28	7	142927390 to 143065411	143056351 to 143056913	dup
12	29	7	143178780 to 143328165	143202762 to 143315906	dup
12	30	7	143332265 to 143438661	143340781 to 143434137	dup
12	31	7	143441827 to 143582864	143445122 to 143514962	dup
12	32	8	20685256 to 20930810	20734633 to 20902429	dup
12	33	8	20952633 to 21370487	20996100 to 21351936	dup
12	34	8	39341524 to 39535655	39356595 to 39511632	del
12	35	10	89148059 to 89241227	89178988 to 89199763	amp
12	36	11	55118214 to 55207305	55124730 to 55200744	del
12	37	11	70513116 to 70534691	70519863 to 70530722	del
12	38	12	7963159 to 8036400	7969578 to 8009244	del
12	39	12	9452803 to 9626736	9528590 to 9613074	h_del
12	40	12	10464018 to 10497371	10465787 to 10493984	dup
12	41	12	11393473 to 11495428	11404653 to 11466807	dup
12	42	14	73060301 to 73106558	73071404 to 73104572	dup
12	43	14	105398979 to 105447369	105405952 to 105441874	dup
12	44	14	105594189 to 105654998	105602756 to 105643293	dup
12	45	14	105845658 to 105881279	105857193 to 105873009	del
12	46	14	106216726 to 106260876	106223137 to 106251081	dup
12	47	15	30965692 to 31034732	30972796 to 31019207	dup
12	48	16	33280759 to 33316641	33288352 to 33300400	del
12	49	16	33495501 to 33533440	33507497 to 33527454	del
12	50	16	34339543 to 34445071	34369010 to 34422716	del
12	51	16	88690571 to 59739	29169 to 48539	del
12	52	17	66107 to 108208	76263 to 96559	del
12	53	17	40901702 to 41062669	40926154 to 41041674	dup
12	54	17	41566540 to 41610132	41577520 to 41599011	del
12	55	17	77432294 to 77478901	77442683 to 77442683	del
12	56	17	77503378 to 77535412	77503673 to 77519913	del
12	57	19	40539029 to 40556205	40543992 to 40548081	amp
12	58	19	56816785 to 56859204	56831724 to 56850433	del
12	59	20	57727183 to 57766758	57734633 to 57757258	del
12	60	22	21376186 to 21575829	21386562 to 21568861	dup
12	61	22	22671374 to 22677959	22677959 to 22677959	dup
13	1	1	12793618 to 12841351	12822189 to 12840011	del
13	2	1	103899771 to 104108153	103909053 to 103965274	dup
13	3	1	246794522 to 246805521	246795223 to 246795223	del
13	4	1	246812523 to 246880850	246822838 to 246874992	del
13	5	2	34539740 to 34627348	34556434 to 34608979	del
13	6	3	101837302 to 101942255	101843382 to 101934035	dup
13	7	3	163987457 to 164112873	163997228 to 164101776	del
13	8	4	68905670 to 69114068	69057735 to 69097336	dup
13	9	4	69120805 to 69657500	69139037 to 69643272	dup
13	10	4	70184190 to 70296172	70188454 to 70264689	dup
13	11	5	36236069 to 36409966	36243089 to 36375004	dup
13	12	5	69274433 to 70345552	69741318 to 70343857	del
13	13	6	32558677 to 32629848	32567382 to 32605300	dup
13	14	6	78983276 to 79133892	79035891 to 79101978	dup
13	15	6	165640218 to 165664947	165645537 to 165657596	del
13	16	7	141408013 to 141453012	141413352 to 141452085	dup
13	17	7	142164247 to 142178751	142167901 to 142178220	h_del
13	18	8	12077339 to 12448374	12276178 to 12285464	amp
13	19	8	39363050 to 39488281	39368509 to 39481985	del
13	20	8	39493887 to 39535655	39499752 to 39511632	del
13	21	10	135108641 to 135252519	135117546 to 135237794	dup
13	22	11	5738494 to 5777496	5742476 to 5766615	h_del
13	23	11	7762277 to 7803570	7774067 to 7797993	dup
13	24	11	55118214 to 55207305	55124730 to 55200744	dup
13	25	11	134099088 to 134136415	134105421 to 134128781	dup
13	26	12	9452803 to 9626736	9528590 to 9613074	h_del
13	27	14	105398979 to 105422205	105405952 to 105413708	amp
13	28	14	105594189 to 105654998	105602756 to 105643293	dup
13	29	14	105724107 to 105799261	105736164 to 105794161	dup
13	30	15	18752131 to 19215427	18790589 to 19206779	dup
13	31	15	19227549 to 19952195	19235401 to 19943194	dup
13	32	15	19963175 to 20249886	19970687 to 20220416	dup
13	33	17	30701599 to 30762521	30706719 to 30755618	del
13	34	17	30772408 to 30804065	30778945 to 30797213	del
13	35	17	41515622 to 41841187	41521544 to 41706870	dup
13	36	19	40539029 to 40556205	40543992 to 40548081	amp
13	37	19	59414645 to 59446274	59427018 to 59440274	del
13	38	20	14277060 to 14343797	14285858 to 14335648	dup
13	39	22	37683516 to 37689058	37689058 to 37689058	dup
14	1	1	12776479 to 12841351	12789063 to 12840011	del
14	2	1	17104345 to 17164768	17114337 to 17157415	dup
14	3	1	147213294 to 147475854	147307637 to 147458669	dup
14	4	1	159786265 to 159895967	159791446 to 159890857	dup
14	5	1	246688566 to 246713357	246696388 to 246711305	del
14	6	1	246755225 to 246805521	246794522 to 246795223	dup
14	7	1	246812523 to 246880850	246822838 to 246874992	dup
14	8	2	32480016 to 32513992	32496047 to 32504230	del
14	9	2	32519984 to 32557276	32531218 to 32548723	del
14	10	2	32564277 to 32588320	32572151 to 32578239	del
14	11	2	32596907 to 32696811	32608307 to 32686168	del
14	12	2	32712425 to 32742980	32718904 to 32737022	del
14	13	2	32750852 to 32781516	32757415 to 32772603	del
14	14	2	32812404 to 32856392	32822023 to 32847049	del
14	15	2	32865684 to 32927818	32871072 to 32916239	del
14	16	2	33008263 to 33054999	33017315 to 33041064	del
14	17	2	33080437 to 33139801	33093716 to 33128874	del
14	18	2	34539740 to 34608979	34556434 to 34580533	amp
14	19	2	87229588 to 87735976	87552703 to 87728048	dup
14	20	2	88924973 to 89207763	88932397 to 89145587	dup
14	21	2	89220538 to 89377632	89256456 to 89284248	dup
14	22	3	46761824 to 46841955	46771035 to 46829442	del
14	23	3	174741344 to 174785195	174747656 to 174775059	del
14	24	4	68905670 to 69657500	69057735 to 69643272	del
14	25	5	725942 to 916822	739292 to 905462	del
14	26	5	140196482 to 140228321	140203440 to 140221835	del
14	27	5	180194323 to 180379352	180342860 to 180365950	dup
14	28	6	174815 to 262620	204528 to 252939	dup
14	29	6	29950805 to 30026699	29962849 to 30021894	h_del
14	30	6	32702995 to 32738443	32711957 to 32732764	del
14	31	6	78983276 to 79133892	79035891 to 79101978	del
14	32	7	38259147 to 38276237	38262701 to 38270942	del
14	33	7	38277728 to 38312900	38281765 to 38305379	del
14	34	7	141885050 to 141917079	141892876 to 141911601	del
14	35	7	143514962 to 143705425	143582864 to 143584350	del
14	36	10	100670683 to 100700712	100678817 to 100695568	del
14	37	11	55118214 to 55207305	55124730 to 55200744	dup
14	38	12	9452803 to 9626736	9528590 to 9613074	del
14	39	14	21705879 to 21739283	21719593 to 21734331	del
14	40	14	21863320 to 21951294	21868942 to 21944246	del
14	41	14	21958644 to 22034704	21966870 to 22022060	del
14	42	14	105398979 to 105455799	105405952 to 105447369	dup
14	43	14	105469325 to 105594189	105476748 to 105584008	dup
14	44	14	105602756 to 105643293	105609466 to 105630089	dup
14	45	14	105654998 to 105873009	105672615 to 105863067	dup
14	46	14	105946993 to 105985458	105962305 to 105977946	dup
14	47	14	105994646 to 106141604	106002179 to 106132797	dup
14	48	15	19786655 to 19860116	19805960 to 19845942	dup
14	49	15	19865444 to 19952195	19869705 to 19943194	dup
14	50	15	32511475 to 32594902	32517513 to 32590643	del
14	51	16	2592859 to 2649851	2605126 to 2645485	del
14	52	16	32378126 to 32561819	32481309 to 32553402	dup
14	53	16	33486907 to 33758082	33495501 to 33539023	dup
14	54	17	19433346 to 19495498	19445241 to 19486672	del
14	55	17	31456645 to 31891535	31461588 to 31889297	del
14	56	18	65342290 to 65375155	65359770 to 65367911	amp
14	57	19	56816785 to 56850433	56831724 to 56840346	amp
14	58	22	21079994 to 21165689	21089993 to 21160383	dup
14	59	22	21169644 to 21192103	21173465 to 21189095	dup
14	60	22	21196638 to 21231545	21199700 to 21225479	dup
14	61	22	21376186 to 21513732	21386562 to 21506376	dup
14	62	22	21520214 to 21602645	21529857 to 21588229	dup
14	63	22	28653590 to 28697813	28662258 to 28690455	del
14	64	22	37046810 to 37088266	37054052 to 37081275	dup
14	65	X	2836003 to 2854934	2842747 to 2850957	del
14	66	X	62321946 to 62453817	62390645 to 62434259	h_del
14	67	X	103054367 to 103129950	103072782 to 103129734	dup
14	68	X	103143709 to 103232959	103152319 to 103224150	dup
14	69	X	134568939 to 134643266	134605994 to 134635957	dup
14	70	X	153127027 to 153158679	153158679 to 153158679	amp
15	1	1	72533856 to 72602597	72550248 to 72568009	dup
15	2	1	151027357 to 151040463	151033188 to 151036435	dup
15	3	1	167483267 to 167523140	167493768 to 167507882	dup
15	4	1	194978218 to 195045871	195005520 to 195033552	dup
15	5	2	88932397 to 88984458	88944977 to 88971719	h_del
15	6	2	130410455 to 130453313	130427905 to 130447827	h_del
15	7	2	132093699 to 132223855	132117324 to 132210342	h_del
15	8	3	163987457 to 164038917	163997228 to 164023502	dup
15	9	3	164052484 to 164112873	164067241 to 164101776	dup
15	10	4	78963782 to 79032741	78969432 to 79023641	dup
15	11	4	79040612 to 79078575	79049463 to 79068220	dup
15	12	4	134299443 to 134330823	134303559 to 134317661	h_del
15	13	4	134348068 to 134536702	134367871 to 134509795	h_del
15	14	5	745859 to 826044	763494 to 819038	h_del
15	15	5	837253 to 916822	848744 to 905462	h_del
15	16	5	69274433 to 70343857	69741318 to 69767948	dup
15	17	5	150166447 to 150209789	150185190 to 150201145	dup
15	18	5	180194323 to 180362342	180342860 to 180355807	dup
15	19	6	174815 to 262620	204528 to 252939	h_del
15	20	6	78983276 to 79101978	79035891 to 79079988	dup
15	21	7	38276237 to 38335964	38277728 to 38318910	dup
15	22	7	133414697 to 133459759	133439454 to 133447868	dup
15	23	7	141408013 to 141453012	141413352 to 141452085	h_del
15	24	8	39341524 to 39511632	39356595 to 39505256	dup
15	25	8	100373146 to 100419910	100381823 to 100413534	dup
15	26	9	43165653 to 43599449	43445839 to 43550676	h_del
15	27	9	112060652 to 112074405	112064860 to 112069192	dup
15	28	11	5738494 to 5766615	5742476 to 5762182	dup
15	29	11	7757329 to 7803570	7762277 to 7797993	h_del
15	30	11	55118214 to 55200744	55124730 to 55194990	dup
15	31	12	435020 to 583697	444988 to 576938	h_del
15	32	12	9452803 to 9613074	9528590 to 9585156	dup
15	33	14	18187154 to 19505698	18504575 to 19497023	h_del
15	34	14	21719593 to 21759503	21727722 to 21748129	dup
15	35	14	21803299 to 21835358	21810635 to 21830693	dup
15	36	14	21863320 to 21907399	21868942 to 21902353	dup
15	37	14	21920051 to 22034704	21931667 to 22022060	dup
15	38	14	105398979 to 105469325	105405952 to 105467525	h_del
15	39	14	105594189 to 105680951	105602756 to 105672615	h_del
15	40	14	105724107 to 105812803	105736164 to 105799261	h_del
15	41	14	106216726 to 106268973	106223137 to 106260876	h_del
15	42	15	18454050 to 18752131	18657388 to 18741716	h_del
15	43	15	18790589 to 19215427	18810004 to 19206779	h_del
15	44	15	19227549 to 19819961	19235401 to 19805960	h_del
15	45	15	19869705 to 19927262	19874690 to 19910867	h_del
15	46	15	36073750 to 36116509	36087941 to 36100472	dup
15	47	16	32378126 to 32561819	32481309 to 32553402	h_del
15	48	16	33205648 to 33477679	33280759 to 33472086	h_del
15	49	16	33486907 to 33875313	33495501 to 33758082	h_del
15	50	16	34297461 to 34685270	34339543 to 34634686	h_del
15	51	19	20383210 to 20510787	20422576 to 20493401	dup
15	52	19	38174374 to 38224496	38182485 to 38215548	h_del
15	53	19	40539029 to 40556205	40543992 to 40548081	del
15	54	20	14277060 to 14343797	14285858 to 14335648	h_del
15	55	21	46914686 to 15019428	14504218 to 14884298	h_del
15	56	22	22671374 to 22731196	22677959 to 22725305	dup
15	57	22	37683516 to 37723010	37689058 to 37718669	h_del
15	58	X	148720028 to 148739051	148739051 to 148739051	h_del
16	1	1	25457903 to 25541997	25482036 to 25536086	dup
16	2	1	150823073 to 150857070	150836484 to 150852858	dup
16	3	3	89473678 to 89509246	89488409 to 89499433	dup
16	4	3	163987457 to 164038917	163997228 to 164023502	dup
16	5	3	164052484 to 164112873	164067241 to 164101776	dup
16	6	3	174741344 to 174767241	174747656 to 174761036	dup
16	7	4	68905670 to 69114068	69057735 to 69097336	h_del
16	8	4	69120805 to 69657500	69139037 to 69643272	h_del
16	9	4	70130975 to 70299545	70159690 to 70296172	h_del
16	10	4	78963782 to 79011907	78969432 to 79004213	dup
16	11	4	79023641 to 79049463	79032741 to 79040612	dup
16	12	4	79057829 to 79094411	79068220 to 79078575	dup
16	13	5	786455 to 848744	802518 to 837253	h_del
16	14	5	37475302 to 37510190	37491462 to 37501489	del
16	15	5	69274433 to 70422297	69741318 to 70345552	dup
16	16	5	110437054 to 110491287	110445097 to 110484072	h_del
16	17	5	150166447 to 150209789	150185190 to 150201145	dup
16	18	5	180194323 to 180365950	180342860 to 180362342	dup
16	19	6	174815 to 252939	204528 to 238441	h_del
16	20	6	29950805 to 30010234	29962849 to 30004636	dup
16	21	6	32600962 to 32634044	32605300 to 32629848	dup
16	22	6	57648021 to 57837153	57683389 to 57804997	h_del
16	23	6	57869378 to 58261050	57891371 to 58162958	h_del
16	24	6	58656267 to 58764418	58721961 to 58721961	dup
16	25	6	58788688 to 62992723	62040890 to 62985085	h_del
16	26	6	168068481 to 168362308	168086690 to 168349663	h_del
16	27	7	133414697 to 133459759	133439454 to 133447868	dup
16	28	7	141408013 to 141453012	141413352 to 141452085	h_del
16	29	7	141687978 to 141720324	141705163 to 141711513	dup
16	30	8	7701787 to 7789937	7729311 to 7747772	del
16	31	8	39363050 to 39511632	39368509 to 39505256	dup
16	32	11	5738494 to 5766615	5742476 to 5762182	dup
16	33	11	7757329 to 7803570	7762277 to 7797993	h_del
16	34	11	46452300 to 46556257	46462434 to 46548912	dup
16	35	12	47961285 to 47971849	47964921 to 47968365	dup
16	36	14	19090564 to 19505698	19154992 to 19497023	h_del
16	37	14	73060301 to 73104572	73071404 to 73092018	h_del
16	38	14	105398979 to 105441874	105405952 to 105432521	h_del
16	39	14	105594189 to 105654998	105602756 to 105643293	h_del
16	40	14	105708209 to 105823416	105724107 to 105818290	h_del
16	41	15	19121757 to 19146596	19130748 to 19137963	h_del
16	42	15	19162213 to 19227549	19171383 to 19215427	h_del
16	43	15	19355643 to 19407585	19365375 to 19397326	h_del
16	44	15	19418600 to 19805960	19427350 to 19786655	h_del
16	45	15	19869705 to 19933992	19874690 to 19927262	h_del
16	46	16	32378126 to 32545350	32481309 to 32534410	h_del
16	47	16	33486907 to 33875313	33495501 to 33758082	h_del
16	48	17	41566540 to 41624471	41577520 to 41610132	h_del
16	49	17	41644979 to 42049540	41700762 to 41983407	h_del
16	50	18	65342290 to 65375155	65359770 to 65367911	dup
16	51	19	40539029 to 40556205	40543992 to 40548081	del
16	52	19	59414645 to 1557784	59427018 to 1546858	dup
16	53	20	14277060 to 37723010	14285858 to 37718669	h_del
16	54	X	74363741 to 74383616	74383616 to 74383616	h_del
17	1	1	16719747 to 16884678	16799334 to 16877283	h_del
17	2	1	102401238 to 102666355	102429242 to 102622311	dup
17	3	1	211063091 to 211082419	211070042 to 211076091	dup
17	4	2	88924973 to 88984458	88932397 to 88971719	h_del
17	5	2	165536552 to 165576760	165544847 to 165566279	h_del
17	6	2	227946001 to 227990692	227952131 to 227973265	h_del
17	7	3	174741344 to 174767241	174747656 to 174761036	dup
17	8	3	196656498 to 196929805	196904349 to 196924340	h_del
17	9	3	196933317 to 196978235	196942158 to 196968244	h_del
17	10	4	68905670 to 69643272	69057735 to 69165814	dup
17	11	4	78963782 to 79011907	78969432 to 79004213	dup
17	12	4	79023641 to 79094411	79032741 to 79078575	dup
17	13	5	12272096 to 12873052	12313192 to 12835355	dup
17	14	5	69274433 to 70345552	69741318 to 70343857	dup
17	15	6	174815 to 262620	204528 to 252939	h_del
17	16	6	29975388 to 30010234	29981930 to 30004636	dup
17	17	6	57648021 to 58162958	57683389 to 58122432	h_del
17	18	6	58764418 to 62992723	58788688 to 62985085	h_del
17	19	6	78983276 to 79133892	79035891 to 79101978	h_del
17	20	6	165640218 to 165657596	165645537 to 165650610	dup
17	21	7	133414697 to 133459759	133439454 to 133447868	dup
17	22	7	141408013 to 141453012	141413352 to 141452085	h_del
17	23	7	141687978 to 141720324	141705163 to 141711513	dup
17	24	8	7701787 to 8132139	7729311 to 8117271	h_del
17	25	8	39363050 to 39511632	39368509 to 39505256	dup
17	26	8	47062121 to 47693177	47575650 to 47658706	h_del
17	27	10	46384979 to 46423080	46396163 to 46414875	dup
17	28	10	46427571 to 46473500	46431590 to 46462545	dup
17	29	10	46480635 to 46568496	46494808 to 46558272	dup
17	30	11	4195010 to 4350150	4219393 to 4343816	h_del
17	31	11	55118214 to 55207305	55124730 to 55200744	h_del
17	32	12	10465787 to 10493984	10474925 to 10484956	dup
17	33	12	47961285 to 47971849	47964921 to 47968365	dup
17	34	13	36964477 to 37023206	36989091 to 37013383	dup
17	35	13	56650373 to 56691355	56658479 to 56673183	dup
17	36	14	105398979 to 105441874	105405952 to 105432521	h_del
17	37	14	105594189 to 105672615	105602756 to 105654998	h_del
17	38	14	105708209 to 105818290	105724107 to 105812803	h_del
17	39	14	105845658 to 105881279	105857193 to 105873009	dup
17	40	14	105934843 to 106002179	105946993 to 105994646	dup
17	41	14	106216726 to 106268973	106223137 to 106260876	h_del
17	42	15	18790589 to 19235401	18810004 to 19227549	h_del
17	43	15	19281889 to 19860116	19291749 to 19845942	h_del
17	44	15	19869705 to 19882711	19874690 to 19879661	h_del
17	45	15	19886840 to 19963175	19910867 to 19952195	h_del
17	46	15	22163893 to 22329016	22232458 to 22289273	h_del
17	47	16	32378126 to 32745412	32481309 to 32561819	h_del
17	48	16	33205648 to 33373002	33280759 to 33316641	h_del
17	49	16	33486907 to 34685270	33495501 to 34634686	h_del
17	50	16	68706240 to 68754234	68710277 to 68751390	dup
17	51	17	41644979 to 42049540	41700762 to 41983407	h_del
17	52	19	21740163 to 21768437	21753258 to 21759877	dup
17	53	19	40539029 to 40556205	40543992 to 40548081	del
17	54	19	56816785 to 56850433	56831724 to 56840346	dup
17	55	19	59414645 to 59440274	59427018 to 59434159	dup
17	56	20	1506379 to 1557784	1516966 to 1546858	h_del
17	57	20	14277060 to 14343797	14285858 to 14335648	h_del
17	58	22	37683516 to 37723010	37689058 to 37718669	h_del
18	1	1	25457903 to 25505750	25482036 to 25488923	dup
18	2	1	147213294 to 147357754	147307637 to 147329819	dup
18	3	1	150819451 to 150857070	150823073 to 150852858	dup
18	4	2	88924973 to 88984458	88932397 to 88971719	h_del
18	5	2	130410455 to 130453313	130427905 to 130447827	h_del
18	6	3	75799957 to 75896020	75845446 to 75875904	h_del
18	7	3	76775901 to 76846953	76799534 to 76821454	dup
18	8	3	174741344 to 70299545	174747656 to 70296172	dup
18	9	4	78963782 to 79011907	78969432 to 79004213	dup
18	10	4	79049463 to 79078575	79057829 to 79068220	dup
18	11	5	17570523 to 17685501	17647063 to 17674967	dup
18	12	5	69274433 to 70345552	69741318 to 70343857	dup
18	13	5	140196482 to 140221835	140203440 to 140216524	dup
18	14	6	174815 to 262620	204528 to 252939	h_del
18	15	6	29950805 to 30004636	29962849 to 29995247	dup
18	16	6	31385778 to 31425144	31395330 to 31418006	dup
18	17	6	32600962 to 32732764	32605300 to 32728487	dup
18	18	6	62500613 to 62531372	62510929 to 62520084	dup
18	19	6	78983276 to 79133892	79035891 to 79101978	h_del
18	20	6	165640218 to 165657596	165645537 to 165650610	dup
18	21	7	133414697 to 133459759	133439454 to 133447868	dup
18	22	7	141408013 to 141453012	141413352 to 141452085	h_del
18	23	7	143514962 to 143705425	143582864 to 143584350	dup
18	24	8	39363050 to 39511632	39368509 to 39505256	dup
18	25	8	137737806 to 137952089	137762418 to 137919308	dup
18	26	11	5738494 to 5766615	5742476 to 5762182	dup
18	27	11	55118214 to 55207305	55124730 to 55200744	h_del
18	28	12	9452803 to 9626736	9528590 to 9613074	h_del
18	29	12	47961285 to 47971849	47964921 to 47968365	dup
18	30	14	18537177 to 18864561	18624383 to 18642252	h_del
18	31	14	19090564 to 19505698	19154992 to 19497023	h_del
18	32	14	105398979 to 105441874	105405952 to 105432521	h_del
18	33	14	105584008 to 105654998	105594189 to 105643293	h_del
18	34	14	105701420 to 105787390	105708209 to 105776293	h_del
18	35	15	18790589 to 19121757	18810004 to 19109124	h_del
18	36	15	19833542 to 19963175	19845942 to 19952195	h_del
18	37	16	21444431 to 21507188	21448093 to 21501073	dup
18	38	16	33486907 to 33758082	33495501 to 33539023	h_del
18	39	17	41566540 to 41624471	41577520 to 41610132	h_del
18	40	17	41644979 to 42049540	41700762 to 41983407	h_del
18	41	18	20446429 to 20556926	20462822 to 20539561	dup
18	42	20	1499034 to 1557784	1506379 to 1546858	h_del
18	43	20	14277060 to 14343797	14285858 to 14335648	h_del
18	44	20	14807577 to 14884522	14823711 to 14876568	dup
18	45	20	62379059 to 9931866	9896630 to 9920838	dup
18	46	22	22671374 to 22731196	22677959 to 22725305	dup
18	47	22	37683516 to 37723010	37689058 to 37718669	h_del
18	48	22	41260534 to 41303616	41274958 to 41299025	h_del
18	49	X	29861478 to 29869725	29869725 to 29869725	h_del
19	1	1	25457903 to 25536086	25482036 to 25529549	dup
19	2	2	88932397 to 88984458	88944977 to 88971719	h_del
19	3	2	89001727 to 89145587	89009521 to 89104501	h_del
19	4	2	242565932 to 242602220	242572731 to 242596654	dup
19	5	2	242608960 to 242689978	242622792 to 242677069	dup
19	6	3	174741344 to 174767241	174747656 to 174761036	dup
19	7	4	3314415 to 3341510	3325525 to 3334744	dup
19	8	4	62208114 to 62250459	62214070 to 62242263	dup
19	9	4	68905670 to 69657500	69057735 to 69643272	h_del
19	10	4	70130975 to 70299545	70159690 to 70296172	h_del
19	11	4	78963782 to 78995025	78969432 to 78979182	dup
19	12	5	745859 to 837253	763494 to 826044	h_del
19	13	5	150166447 to 150209789	150185190 to 150201145	dup
19	14	5	180342860 to 180379352	180351118 to 180365950	h_del
19	15	6	32519935 to 32629848	32558677 to 32605300	h_del
19	16	6	32711957 to 32745036	32718991 to 32738443	h_del
19	17	6	162427045 to 162734579	162445366 to 162727845	dup
19	18	7	29165049 to 29406881	29178538 to 29398227	h_del
19	19	7	29418768 to 29519225	29423827 to 29506145	h_del
19	20	7	64284236 to 64358181	64317152 to 64351882	dup
19	21	7	64372370 to 64490477	64381337 to 64485587	dup
19	22	7	64502659 to 64612157	64503449 to 64582493	dup
19	23	7	133414697 to 133459759	133439454 to 133447868	dup
19	24	7	141408013 to 141453012	141413352 to 141452085	h_del
19	25	7	143514962 to 143705425	143582864 to 143584350	dup
19	26	8	12077339 to 12448374	12276178 to 12285464	del
19	27	8	39363050 to 39488281	39368509 to 39481985	dup
19	28	8	39493887 to 39511632	39499752 to 39505256	dup
19	29	9	71281397 to 71326927	71288892 to 71316891	h_del
19	30	11	7762277 to 7803570	7774067 to 7797993	h_del
19	31	11	55118214 to 55200744	55124730 to 55194990	dup
19	32	11	89344807 to 89482692	89400624 to 89470943	h_del
19	33	12	7915622 to 7969578	7922474 to 7963159	h_del
19	34	12	7979868 to 8056718	7983887 to 8036400	h_del
19	35	12	47961285 to 47971849	47964921 to 47968365	dup
19	36	14	73071404 to 73092018	73075500 to 73082250	dup
19	37	14	105398979 to 105455799	105405952 to 105447369	h_del
19	38	14	105461412 to 105524683	105467525 to 105515561	h_del
19	39	14	105536949 to 105863067	105545545 to 105857193	h_del
19	40	14	105946993 to 105994646	105962305 to 105985458	dup
19	41	14	106216726 to 106268973	106223137 to 106260876	h_del
19	42	15	22055553 to 22138119	22077517 to 22077517	h_del
19	43	15	22163893 to 22364310	22232458 to 22346355	h_del
19	44	15	32511475 to 32544263	32517513 to 32536263	dup
19	45	15	32553674 to 32590643	32563500 to 32578483	dup
19	46	16	3143106 to 3195143	3159477 to 3186299	h_del
19	47	16	32378126 to 32545350	32481309 to 32534410	h_del
19	48	16	33486907 to 33875313	33495501 to 33758082	h_del
19	49	16	34297461 to 34605030	34339543 to 34584793	h_del
19	50	17	41515622 to 41983407	41521544 to 41841187	h_del
19	51	18	65342290 to 65375155	65359770 to 65367911	dup
19	52	19	40539029 to 40556205	40543992 to 40548081	del
19	53	20	#N/A	#N/A	h_del
20	1	1	194978218 to 195033552	195005520 to 195026703	dup
20	2	1	195045871 to 195091758	195048208 to 195067764	dup
20	3	2	108835796 to 108878427	108850705 to 108861948	dup
20	4	3	174741344 to 174767241	174747656 to 174761036	dup
20	5	3	193425666 to 193453558	193439462 to 193446184	dup
20	6	4	68905670 to 69657500	69057735 to 69643272	h_del
20	7	4	70130975 to 70299545	70159690 to 70296172	h_del
20	8	4	78963782 to 79011907	78969432 to 79004213	dup
20	9	4	79049463 to 79094411	79057829 to 79078575	dup
20	10	5	69274433 to 70622715	69741318 to 70422297	dup
20	11	6	174815 to 262620	204528 to 252939	h_del
20	12	6	32600962 to 32634044	32605300 to 32629848	dup
20	13	7	141408013 to 141453012	141413352 to 141452085	h_del
20	14	8	15437205 to 15466032	15447810 to 15453544	dup
20	15	11	5738494 to 5766615	5742476 to 5762182	dup
20	16	11	7762277 to 7803570	7774067 to 7797993	h_del
20	17	11	55118214 to 55207305	55124730 to 55200744	h_del
20	18	12	47961285 to 47977721	47964921 to 47971849	dup
20	19	14	18187154 to 19090564	18504575 to 18864561	h_del
20	20	14	19216369 to 19362145	19268776 to 19350230	h_del
20	21	14	19388122 to 19420732	19397709 to 19414714	h_del
20	22	14	19433191 to 19505698	19446048 to 19497023	h_del
20	23	14	105398979 to 105422205	105405952 to 105413708	del
20	24	14	105594189 to 105654998	105602756 to 105643293	h_del
20	25	14	105708209 to 105812803	105724107 to 105799261	h_del
20	26	14	105845658 to 105881279	105857193 to 105873009	dup
20	27	15	18790589 to 19121757	18810004 to 19109124	h_del
20	28	15	19845942 to 19963175	19860116 to 19952195	h_del
20	29	15	22021181 to 22077517	22038880 to 22055553	dup
20	30	16	32378126 to 32748349	32481309 to 32745412	h_del
20	31	16	33205648 to 33316641	33280759 to 33300400	h_del
20	32	16	33486907 to 33875313	33495501 to 33758082	h_del
20	33	17	31461588 to 31889297	31468896 to 31504564	h_del
20	34	17	41515622 to 41983407	41521544 to 41841187	h_del
20	35	19	6899824 to 6970058	6909753 to 6964360	dup
20	36	19	40539029 to 40556205	40543992 to 40548081	del
20	37	19	59414645 to 59440274	59427018 to 59434159	dup
20	38	20	1499034 to 1557784	1506379 to 1546858	h_del
20	39	20	14277060 to 14343797	14285858 to 14335648	h_del
20	40	22	22671374 to 22731196	22677959 to 22725305	dup
20	41	22	23984069 to 24056350	23994618 to 24047238	h_del
20	42	22	24181763 to 24268562	24187585 to 24254026	h_del
20	43	22	37683516 to 37723010	37689058 to 37718669	h_del
20	44	X	153067477 to 153127027	153127027 to 153127027	h_del
21	1	1	72533856 to 72602597	72550248 to 72568009	dup
21	2	1	103932025 to 104108153	103956767 to 103965274	dup
21	3	1	150823073 to 150857070	150836484 to 150852858	dup
21	4	1	151027357 to 151040463	151033188 to 151036435	dup
21	5	1	194978218 to 195033552	195005520 to 195026703	dup
21	6	2	88924973 to 89001727	88932397 to 88995175	h_del
21	7	2	89009521 to 89145587	89015715 to 89104501	h_del
21	8	2	130410455 to 130453313	130427905 to 130447827	h_del
21	9	2	132130850 to 132210342	132152891 to 132206366	h_del
21	10	3	46761824 to 46829442	46771035 to 46823673	dup
21	11	3	89473678 to 89509246	89488409 to 89499433	dup
21	12	3	174741344 to 174767241	174747656 to 174761036	dup
21	13	4	68905670 to 69114068	69057735 to 69097336	h_del
21	14	4	69120805 to 69657500	69139037 to 69643272	h_del
21	15	4	70130975 to 70299545	70159690 to 70296172	h_del
21	16	4	78963782 to 79078575	78969432 to 79068220	dup
21	17	5	69767948 to 70693444	70343857 to 70622715	h_del
21	18	5	180342860 to 180379352	180351118 to 180365950	h_del
21	19	6	32519935 to 32629848	32558677 to 32605300	h_del
21	20	6	78983276 to 79133892	79035891 to 79101978	h_del
21	21	6	165640218 to 165657596	165645537 to 165650610	dup
21	22	7	133414697 to 133459759	133439454 to 133447868	dup
21	23	7	141408013 to 141453012	141413352 to 141452085	h_del
21	24	7	143501811 to 143705425	143514962 to 143584350	dup
21	25	8	39363050 to 39511632	39368509 to 39505256	dup
21	26	8	57206447 to 57275321	57215366 to 57268695	h_del
21	27	9	569790 to 593494	577359 to 584647	dup
21	28	9	112060652 to 112074405	112064860 to 112069192	dup
21	29	11	7762277 to 7803570	7774067 to 7797993	h_del
21	30	12	11393473 to 11444721	11404653 to 11430887	dup
21	31	12	47961285 to 47971849	47964921 to 47968365	dup
21	32	14	18537177 to 18864561	18624383 to 18642252	h_del
21	33	14	19090564 to 19505698	19154992 to 19497023	h_del
21	34	14	21863320 to 21881623	21868942 to 21873825	dup
21	35	14	21966870 to 21993784	21973343 to 21981288	dup
21	36	14	56268037 to 56341548	56290639 to 56337975	dup
21	37	14	105398979 to 105441874	105405952 to 105432521	h_del
21	38	14	105447369 to 105524683	105455799 to 105515561	h_del
21	39	14	105536949 to 105654998	105545545 to 105643293	h_del
21	40	14	105701420 to 105812803	105708209 to 105799261	h_del
21	41	15	18454050 to 18752131	18657388 to 18741716	h_del
21	42	15	18790589 to 19235401	18810004 to 19227549	h_del
21	43	15	19281889 to 19321280	19291749 to 19305294	h_del
21	44	15	19338183 to 19952195	19347444 to 19943194	h_del
21	45	16	18069609 to 18687416	18205105 to 18599499	h_del
21	46	16	33280759 to 33316641	33288352 to 33300400	h_del
21	47	16	33495501 to 33758082	33507497 to 33539023	h_del
21	48	16	34297461 to 34685270	34339543 to 34634686	h_del
21	49	16	68679377 to 68754234	68706240 to 68751390	dup
21	50	16	72937352 to 73012768	72955519 to 72964783	dup
21	51	17	41533641 to 41841187	41544224 to 41706870	h_del
21	52	19	40539029 to 40556205	40543992 to 40548081	del
21	53	20	1499034 to 1557784	1506379 to 1546858	h_del
21	54	20	14277060 to 43669640	14285858 to 43666311	h_del
21	55	21	46914686 to 15019428	14504218 to 14884298	h_del
21	56	22	17086001 to 17299942	17270271 to 17295409	h_del
21	57	22	17304015 to 17334722	17318161 to 17333012	h_del
21	58	22	17343306 to 17409602	17348891 to 17403824	h_del
21	59	22	22671374 to 22677959	22677959 to 22677959	dup
22	1	1	12762774 to 13647633	12776479 to 13101056	dup
22	2	1	16236840 to 16265269	16242789 to 16260159	del
22	3	1	16964267 to 17148592	17082119 to 17130528	del
22	4	1	72523186 to 72652073	72533856 to 72602597	dup
22	5	1	116950996 to 117008723	116970390 to 117001475	del
22	6	1	150819451 to 150861724	150823073 to 150857070	h_del
22	7	1	151026228 to 151044659	151027357 to 151040463	h_del
22	8	1	246755225 to 246805521	246794522 to 246795223	dup
22	9	1	246812523 to 246890704	246822838 to 246880850	dup
22	10	2	32356228 to 32397932	32361923 to 32390397	del
22	11	2	32414378 to 32504230	32421620 to 32496047	del
22	12	2	32513992 to 32640703	32519984 to 32628022	del
22	13	2	51144468 to 51222630	51154781 to 51212326	del
22	14	2	51316337 to 51410160	51329968 to 51381919	del
22	15	2	51495943 to 51538676	51508648 to 51525862	del
22	16	2	51555452 to 51689071	51565656 to 51665999	del
22	17	2	51700454 to 51893247	51724682 to 51867924	del
22	18	2	51906913 to 51966666	51927527 to 51953207	del
22	19	2	52084156 to 52193100	52100202 to 52177913	del
22	20	2	52219140 to 52312174	52229518 to 52288138	del
22	21	2	52978045 to 53115318	52996117 to 53088812	del
22	22	2	88910647 to 89145587	88924973 to 89104501	dup
22	23	3	885017 to 949222	902548 to 937669	del
22	24	3	965190 to 1071712	982068 to 1063205	del
22	25	3	1084890 to 1128789	1092683 to 1120284	del
22	26	3	1237393 to 1312273	1246144 to 1304846	del
22	27	3	1322293 to 1358619	1331952 to 1353116	del
22	28	3	1402460 to 1458772	1410394 to 1439291	del
22	29	3	1514248 to 1638096	1533505 to 1626419	del
22	30	3	1705955 to 1757481	1715913 to 1744443	del
22	31	3	46761824 to 46841955	46771035 to 46829442	dup
22	32	3	164023502 to 164123806	164038917 to 164112873	dup
22	33	3	174721900 to 174785195	174736125 to 174775059	dup
22	34	4	68905670 to 69114068	69057735 to 69097336	del
22	35	4	69120805 to 69657500	69139037 to 69643272	del
22	36	4	70207135 to 70255674	70216707 to 70237778	del
22	37	4	190749363 to 190907865	190780239 to 190899523	dup
22	38	5	771310 to 837253	786455 to 826044	dup
22	39	5	140196482 to 140228321	140203440 to 140221835	dup
22	40	5	180194323 to 180362342	180342860 to 180355807	dup
22	41	5	180365950 to 180431708	180379352 to 180424268	dup
22	42	6	78983276 to 79133892	79035891 to 79101978	dup
22	43	7	38259147 to 38343026	38262701 to 38335964	del
22	44	7	133414697 to 133465974	133439454 to 133459759	del
22	45	7	141408013 to 141453012	141413352 to 141452085	del
22	46	8	15437205 to 15475696	15447810 to 15466032	del
22	47	8	89749812 to 89831743	89764120 to 89796449	del
22	48	8	100064783 to 100218102	100082337 to 100211675	h_del
22	49	10	100670683 to 100700712	100678817 to 100695568	del
22	50	11	5738494 to 5777496	5742476 to 5766615	dup
22	51	11	5838945 to 5911302	5849760 to 5906060	del
22	52	14	21698018 to 21734331	21705879 to 21727722	del
22	53	14	21810635 to 22022060	21825583 to 22012263	del
22	54	14	69078818 to 69106345	69088190 to 69098569	del
22	55	14	73051686 to 73106558	73060301 to 73104572	dup
22	56	14	105128688 to 105184425	105138794 to 105178535	dup
22	57	14	105204611 to 105280523	105224700 to 105275857	dup
22	58	14	105398979 to 105455799	105405952 to 105447369	dup
22	59	14	105461412 to 105504747	105467525 to 105481933	dup
22	60	14	105584008 to 105654998	105594189 to 105643293	dup
22	61	14	105724107 to 105799261	105736164 to 105794161	dup
22	62	14	105812803 to 105923159	105818290 to 105907191	dup
22	63	15	19786655 to 19874690	19805960 to 19869705	del
22	64	15	19882711 to 19952195	19886840 to 19943194	del
22	65	15	19963175 to 19982333	19970687 to 19976279	del
22	66	15	19988304 to 20220416	20010559 to 20079935	del
22	67	16	54343465 to 54374831	54354643 to 54365385	del
22	68	16	54390012 to 54444069	54400475 to 54437553	dup
22	69	16	74095899 to 74148860	74109031 to 74141966	dup
22	70	17	19445241 to 19495498	19460284 to 19486672	del
22	71	19	20366292 to 20439905	20383210 to 20422576	del
22	72	19	20463727 to 20523656	20474417 to 20510787	del
22	73	20	1506379 to 1557784	1516966 to 1546858	h_del
22	74	22	17021714 to 17274835	17041724 to 17270271	h_del
22	75	22	21506376 to 21513732	21513732 to 21513732	dup
23	1	1	17104345 to 17164768	17114337 to 17157415	dup
23	2	1	25457903 to 25488923	25482036 to 25482036	amp
23	3	1	25505750 to 25547799	25520845 to 25541997	dup
23	4	1	49686346 to 49777837	49694563 to 49771606	h_del
23	5	1	72533856 to 72602597	72550248 to 72568009	amp
23	6	1	103899771 to 103932025	103909053 to 103926458	del
23	7	1	147213294 to 147987813	147307637 to 147978622	dup
23	8	1	150819451 to 150861724	150823073 to 150857070	dup
23	9	1	159786265 to 159895967	159791446 to 159890857	dup
23	10	1	194978218 to 195033552	195005520 to 195026703	del
23	11	2	32480016 to 32564277	32496047 to 32557276	del
23	12	2	32596907 to 32704772	32608307 to 32697011	del
23	13	2	32712425 to 32750852	32718904 to 32742980	del
23	14	2	32781516 to 32865684	32790864 to 32856392	del
23	15	2	33008263 to 33054999	33017315 to 33041064	del
23	16	2	33071907 to 33148227	33080437 to 33139801	del
23	17	2	34539740 to 34608979	34556434 to 34580533	amp
23	18	2	87229588 to 87735976	87552703 to 87728048	dup
23	19	2	88924973 to 89056402	88932397 to 89050026	dup
23	20	2	89078609 to 89220538	89093646 to 89207763	dup
23	21	3	130597079 to 130623449	130604059 to 130618098	del
23	22	3	174741344 to 174775059	174747656 to 174767241	del
23	23	4	68905670 to 69657500	69057735 to 69643272	del
23	24	4	70201666 to 70237778	70207135 to 70227036	del
23	25	5	725942 to 745859	739292 to 739292	del
23	26	5	763494 to 848744	771310 to 837253	del
23	27	5	859176 to 905462	873416 to 894957	del
23	28	5	68868713 to 70345552	69274433 to 70343857	dup
23	29	5	180194323 to 180379352	180342860 to 180365950	dup
23	30	6	174815 to 262620	204528 to 252939	dup
23	31	6	32702995 to 32738443	32711957 to 32732764	del
23	32	6	78983276 to 79133892	79035891 to 79101978	del
23	33	7	38277728 to 38312900	38281765 to 38305379	del
23	34	7	141408013 to 141453012	141413352 to 141452085	dup
23	35	7	142164247 to 142178220	142167901 to 142171618	amp
23	36	7	143514962 to 143705425	143582864 to 143584350	del
23	37	8	39341524 to 39535655	39356595 to 39511632	dup
23	38	10	46480635 to 46545343	46494808 to 46532937	dup
23	39	11	5738494 to 5777496	5742476 to 5766615	h_del
23	40	11	55118214 to 55207305	55124730 to 55200744	dup
23	41	12	9452803 to 9633884	9528590 to 9626736	h_del
23	42	12	10457163 to 10497371	10464018 to 10493984	dup
23	43	12	93990499 to 94055539	94002481 to 94044915	dup
23	44	14	19216369 to 19323579	19268776 to 19317571	dup
23	45	14	19350230 to 19505698	19362145 to 19497023	dup
23	46	14	22000194 to 22034704	22005835 to 22022060	del
23	47	14	73060301 to 73106558	73071404 to 73104572	del
23	48	14	105361835 to 105391340	105369044 to 105384766	dup
23	49	14	105398979 to 105441874	105405952 to 105432521	dup
23	50	14	105469325 to 105515561	105476748 to 105504747	dup
23	51	14	105536949 to 105630089	105545545 to 105623070	dup
23	52	14	105654998 to 105873009	105672615 to 105863067	dup
23	53	14	105946993 to 105994646	105962305 to 105985458	dup
23	54	14	106002179 to 106056612	106017453 to 106048712	dup
23	55	14	106092825 to 106141604	106109195 to 106132797	dup
23	56	14	106216726 to 106268973	106223137 to 106260876	dup
23	57	15	18657388 to 18752131	18683110 to 18741716	del
23	58	15	18848213 to 19130748	18864582 to 19121757	del
23	59	15	19162213 to 19227549	19171383 to 19215427	del
23	60	15	19321280 to 19407585	19338183 to 19397326	del
23	61	15	19418600 to 19537035	19427350 to 19465359	del
23	62	16	32378126 to 32748349	32481309 to 32745412	dup
23	63	16	33424939 to 33477679	33433058 to 33472086	dup
23	64	16	33486907 to 33875313	33495501 to 33758082	dup
23	65	16	34297461 to 34634686	34339543 to 34605030	dup
23	66	16	72937352 to 73022578	72955519 to 73012768	del
23	67	17	31456645 to 31891535	31461588 to 31889297	del
23	68	17	41533641 to 41635536	41544224 to 41624471	dup
23	69	18	65342290 to 65375155	65359770 to 65367911	amp
23	70	19	12343141 to 12387973	12350778 to 12383149	dup
23	71	19	56816785 to 56850433	56831724 to 56840346	amp
23	72	19	59487170 to 59507350	59492650 to 59502178	del
23	73	22	21079994 to 21165689	21089993 to 21160383	dup
23	74	22	21376186 to 21409281	21386562 to 21404393	dup
23	75	22	21417094 to 21513732	21427178 to 21506376	dup
23	76	22	21520214 to 21602645	21529857 to 21588229	dup
23	77	22	22681995 to 22736990	22686690 to 22731196	dup
23	78	X	62321946 to 62390645	62390645 to 62390645	h_del
24	1	1	12776479 to 12841351	12789063 to 12840011	del
24	2	1	25457903 to 25488923	25482036 to 25482036	amp
24	3	1	25505750 to 25547799	25520845 to 25541997	dup
24	4	1	110023268 to 110062339	110033832 to 110057882	del
24	5	1	146375659 to 147203277	147134175 to 147134175	dup
24	6	1	147213294 to 147329819	147307637 to 147307637	amp
24	7	1	147357754 to 147475854	147386918 to 147458669	dup
24	8	1	150823073 to 150861724	150836484 to 150857070	dup
24	9	1	246755225 to 246805521	246794522 to 246795223	dup
24	10	1	246812523 to 246890704	246822838 to 246880850	dup
24	11	2	32519984 to 32557276	32531218 to 32548723	del
24	12	2	32564277 to 32596907	32572151 to 32588320	del
24	13	2	32696811 to 32742980	32697011 to 32737022	del
24	14	2	32750852 to 32790864	32757415 to 32781516	del
24	15	2	32822023 to 32847049	32831262 to 32836817	del
24	16	2	32856392 to 32907228	32865684 to 32891109	del
24	17	2	32916239 to 32975090	32927818 to 32958034	del
24	18	2	34539740 to 34608979	34556434 to 34580533	amp
24	19	2	43372667 to 43413230	43381945 to 43401068	del
24	20	2	87178812 to 87661927	87229588 to 87613207	dup
24	21	2	88924973 to 89220538	88932397 to 89207763	dup
24	22	3	75799957 to 75896020	75845446 to 75875904	dup
24	23	3	152985586 to 153035523	152996121 to 153028963	del
24	24	3	196656498 to 196929805	196904349 to 196924340	dup
24	25	4	68905670 to 69114068	69057735 to 69097336	del
24	26	4	69120805 to 69657500	69139037 to 69643272	del
24	27	4	135127780 to 135414559	135162686 to 135399560	del
24	28	5	725942 to 771310	739292 to 763494	del
24	29	5	786455 to 848744	802518 to 837253	del
24	30	5	859176 to 905462	873416 to 894957	del
24	31	5	150166447 to 150224239	150185190 to 150209789	del
24	32	5	180194323 to 180379352	180342860 to 180365950	dup
24	33	6	174815 to 262620	204528 to 252939	dup
24	34	6	110490286 to 110541274	110507161 to 110530100	del
24	35	7	133414697 to 133465974	133439454 to 133459759	del
24	36	7	141687978 to 141720324	141705163 to 141711513	amp
24	37	8	6929691 to 8132139	7040596 to 8117271	dup
24	38	11	5738494 to 5777496	5742476 to 5766615	dup
24	39	11	55118214 to 55167475	55124730 to 55162949	dup
24	40	11	55173374 to 55207305	55178955 to 55200744	dup
24	41	11	64416379 to 64432852	64420058 to 64427356	del
24	42	11	89296560 to 89482692	89344807 to 89470943	dup
24	43	12	9452803 to 9626736	9528590 to 9613074	h_del
24	44	12	50974444 to 51056070	50977596 to 51050718	dup
24	45	14	18537177 to 18864561	18624383 to 18642252	dup
24	46	14	19090564 to 19505698	19154992 to 19497023	dup
24	47	14	26810803 to 26937397	26838442 to 26908812	del
24	48	14	40670538 to 40779816	40704122 to 40746865	del
24	49	14	69078818 to 69106345	69088190 to 69098569	del
24	50	14	105398979 to 105441874	105405952 to 105432521	dup
24	51	14	105524683 to 105594189	105536949 to 105584008	dup
24	52	14	105602756 to 105643293	105609466 to 105630089	dup
24	53	14	105654998 to 105857193	105672615 to 105845658	dup
24	54	14	105863067 to 105962305	105873009 to 105946993	dup
24	55	14	106002179 to 106086435	106017453 to 106072471	dup
24	56	14	106216726 to 106268973	106223137 to 106260876	dup
24	57	15	18722595 to 19235401	18741716 to 19227549	dup
24	58	15	19281889 to 19435500	19291749 to 19427350	dup
24	59	15	19465359 to 19952195	19537035 to 19943194	dup
24	60	15	19963175 to 20307869	19970687 to 20249886	dup
24	61	16	33205648 to 33300400	33280759 to 33298899	dup
24	62	16	33486907 to 33875313	33495501 to 33758082	dup
24	63	16	34297461 to 34605030	34339543 to 34584793	dup
24	64	16	72937352 to 73022578	72955519 to 73012768	del
24	65	17	31456645 to 31891535	31461588 to 31889297	del
24	66	17	41566540 to 41700762	41577520 to 41644979	dup
24	67	18	65342290 to 65375155	65359770 to 65367911	amp
24	68	19	40539029 to 40562762	40543992 to 40556205	del
24	69	19	56816785 to 56850433	56831724 to 56840346	amp
24	70	20	1506379 to 1557784	1516966 to 1546858	dup
24	71	22	21130870 to 21165689	21136884 to 21160383	dup
24	72	22	21196638 to 21225479	21199700 to 21222487	dup
24	73	22	21235009 to 21284872	21241053 to 21277813	dup
24	74	22	21376186 to 21588229	21386562 to 21575829	dup
24	75	X	62321946 to 62390645	62390645 to 62390645	h_del
25	1	1	25457903 to 25547799	25482036 to 25541997	dup
25	2	1	72533856 to 72602597	72550248 to 72568009	amp
25	3	1	110023268 to 110068307	110033832 to 110062339	del
25	4	1	147213294 to 147357754	147307637 to 147329819	amp
25	5	1	147386918 to 147458669	147421614 to 147438471	amp
25	6	1	150823073 to 150861724	150836484 to 150857070	dup
25	7	1	151026228 to 151044659	151027357 to 151040463	del
25	8	2	32480016 to 32519984	32496047 to 32513992	del
25	9	2	32548723 to 32588320	32557276 to 32578239	del
25	10	2	32596907 to 32628022	32608307 to 32616151	del
25	11	2	32640703 to 32696811	32652426 to 32686168	del
25	12	2	32704772 to 32790864	32712425 to 32781516	del
25	13	2	32856392 to 32891109	32865684 to 32878011	del
25	14	2	32916239 to 32975090	32927818 to 32958034	del
25	15	2	32991312 to 33030410	32998706 to 33017315	del
25	16	2	33080437 to 33148227	33093716 to 33139801	del
25	17	2	34539740 to 34608979	34556434 to 34580533	amp
25	18	2	86975597 to 87661927	87178812 to 87613207	dup
25	19	2	88910647 to 89056402	88924973 to 89050026	dup
25	20	2	89078609 to 89207763	89093646 to 89145587	dup
25	21	2	89220538 to 89377632	89256456 to 89284248	dup
25	22	3	89473678 to 89516057	89488409 to 89509246	h_del
25	23	3	99882361 to 99930391	99893658 to 99924129	del
25	24	3	164023502 to 164123806	164038917 to 164112873	dup
25	25	4	68905670 to 69657500	69057735 to 69643272	del
25	26	4	110821159 to 110838899	110824984 to 110831519	del
25	27	5	725942 to 763494	739292 to 745859	del
25	28	5	771310 to 905462	786455 to 894957	del
25	29	5	68868713 to 70345552	69274433 to 70343857	dup
25	30	5	180194323 to 180379352	180342860 to 180365950	dup
25	31	6	32071823 to 32123032	32082018 to 32119501	del
25	32	6	32711957 to 32738443	32718991 to 32732764	del
25	33	6	33357305 to 33373305	33360021 to 33367581	del
25	34	7	141408013 to 141453012	141413352 to 141452085	h_del
25	35	7	141687978 to 141720324	141705163 to 141711513	amp
25	36	7	142164247 to 142178220	142167901 to 142171618	amp
25	37	7	143501811 to 143705425	143514962 to 143584350	del
25	38	8	7040596 to 7701787	7256229 to 7359040	del
25	39	8	133201119 to 133225313	133213667 to 133219387	amp
25	40	9	110660322 to 110676976	110664379 to 110669955	del
25	41	9	112060652 to 112086263	112064860 to 112074405	del
25	42	10	44610674 to 44704087	44629442 to 44691262	dup
25	43	10	60984817 to 61088752	61031952 to 61080658	del
25	44	11	55112329 to 55207305	55118214 to 55200744	dup
25	45	12	9452803 to 9633884	9528590 to 9626736	h_del
25	46	12	10464018 to 10497371	10465787 to 10493984	dup
25	47	14	19090564 to 19505698	19154992 to 19497023	dup
25	48	14	21993784 to 22022060	22000194 to 22012263	del
25	49	14	69078818 to 69106345	69088190 to 69098569	del
25	50	14	105398979 to 105455799	105405952 to 105447369	dup
25	51	14	105461412 to 105524683	105467525 to 105515561	dup
25	52	14	105536949 to 105643293	105545545 to 105630089	dup
25	53	14	105654998 to 105985458	105672615 to 105977946	dup
25	54	14	105994646 to 106109195	106002179 to 106092825	dup
25	55	14	106216726 to 106268973	106223137 to 106260876	dup
25	56	15	19465359 to 19952195	19537035 to 19943194	dup
25	57	15	19963175 to 20316992	19970687 to 20307869	dup
25	58	15	22163893 to 22289273	22232458 to 22272781	del
25	59	16	28516947 to 28542215	28523145 to 28536745	del
25	60	16	32378126 to 32561819	32481309 to 32553402	del
25	61	16	54354643 to 54379834	54359983 to 54374831	del
25	62	16	54390012 to 54444069	54400475 to 54437553	dup
25	63	16	68710277 to 68795079	68726557 to 68754234	del
25	64	17	31456645 to 31891535	31461588 to 31889297	del
25	65	17	41566540 to 41706870	41577520 to 41700762	dup
25	66	18	65342290 to 65375155	65359770 to 65367911	amp
25	67	19	56816785 to 56850433	56831724 to 56840346	amp
25	68	20	1506379 to 1546858	1516966 to 1539155	del
25	69	21	13342486 to 13582167	13379975 to 13562263	dup
25	70	22	21165689 to 21196638	21169644 to 21192103	dup
25	71	22	21199700 to 21235009	21207681 to 21231545	dup
25	72	22	21417094 to 21452488	21427178 to 21443735	dup
25	73	22	21460395 to 21513732	21470618 to 21506376	dup
25	74	22	21520214 to 21602645	21529857 to 21588229	dup
25	75	X	3215506 to 3268345	3226228 to 3258178	dup
25	76	X	52909690 to 52966148	52916249 to 52921841	del
25	77	X	62321946 to 62453817	62390645 to 62434259	del
25	78	X	63296913 to 63337619	63311382 to 63333183	del
25	79	X	69630857 to 69665439	69639118 to 69659613	del
25	80	X	89326357 to 89740571	89351337 to 89581622	dup
25	81	X	131052542 to 131062675	131062675 to 131062675	del
26	1	1	554268 to 736483	554287 to 639581	del
26	2	1	16964267 to 17094475	17082119 to 17088704	dup
26	3	1	17104345 to 17157415	17114337 to 17148592	dup
26	4	1	25505750 to 25541997	25520845 to 25536086	del
26	5	1	150819451 to 150861724	150823073 to 150857070	dup
26	6	1	153372547 to 153398462	153377888 to 153387614	del
26	7	1	159758730 to 159885469	159762714 to 159876777	dup
26	8	1	194978218 to 195033552	195005520 to 195026703	del
26	9	1	195045871 to 195091758	195048208 to 195067764	del
26	10	1	246755225 to 246805521	246794522 to 246795223	del
26	11	1	246812523 to 246880850	246822838 to 246874992	del
26	12	2	53692461 to 53774603	53723095 to 53767277	del
26	13	2	132093699 to 132210342	132117324 to 132206366	dup
26	14	3	164023502 to 164101776	164038917 to 164086905	del
26	15	3	196656498 to 196978235	196904349 to 196968244	dup
26	16	5	180342860 to 180379352	180351118 to 180365950	del
26	17	6	174815 to 262620	204528 to 252939	dup
26	18	6	32595402 to 32654432	32600962 to 32634044	del
26	19	6	32711957 to 32738443	32718991 to 32732764	del
26	20	6	57704050 to 57837153	57724750 to 57804997	del
26	21	6	57869378 to 58162958	57891371 to 58122432	del
26	22	6	58788688 to 62384068	62040890 to 62363231	del
26	23	6	62408817 to 62454106	62425017 to 62448434	del
26	24	6	62510929 to 62589745	62520084 to 62581052	del
26	25	6	78983276 to 79133892	79035891 to 79101978	del
26	26	6	165640218 to 165664947	165645537 to 165657596	del
26	27	7	304305 to 797378	309505 to 794361	del
26	28	7	64284236 to 64351882	64317152 to 64343985	del
26	29	7	64358181 to 64490477	64364689 to 64485587	del
26	30	7	64502659 to 64612157	64503449 to 64582493	del
26	31	7	64701033 to 64833823	64708295 to 64813767	del
26	32	8	7040596 to 7789937	7256229 to 7747772	dup
26	33	9	112060652 to 112086263	112064860 to 112074405	del
26	34	10	74501741 to 74534384	74508248 to 74522022	del
26	35	10	100670683 to 100700712	100678817 to 100695568	del
26	36	10	122751618 to 122786424	122760448 to 122777587	del
26	37	11	7762277 to 7803570	7774067 to 7797993	del
26	38	11	18896166 to 18966447	18906505 to 18929375	h_del
26	39	12	9452803 to 9633884	9528590 to 9626736	dup
26	40	12	10464018 to 10497371	10465787 to 10493984	dup
26	41	14	18537177 to 19505698	18624383 to 19497023	dup
26	42	14	105398979 to 105432521	105405952 to 105422205	del
26	43	14	105594189 to 105654998	105602756 to 105643293	h_del
26	44	15	18454050 to 19273143	18657388 to 19253730	dup
26	45	15	19281889 to 19465359	19291749 to 19435500	dup
26	46	15	19537035 to 20249886	19786655 to 20220416	dup
26	47	15	22021181 to 22138119	22038880 to 22077517	del
26	48	15	32505423 to 32654561	32511475 to 32628679	dup
26	49	15	41638388 to 41776053	41676219 to 41737960	dup
26	50	16	32004586 to 32561819	32105104 to 32553402	dup
26	51	16	34297461 to 34605030	34339543 to 34584793	dup
26	52	16	68679377 to 68838368	68706240 to 68795079	del
26	53	16	72917554 to 73022578	72933295 to 73012768	del
26	54	17	31456645 to 31889297	31461588 to 31504564	del
26	55	17	41644979 to 41983407	41700762 to 41841187	del
26	56	17	74872990 to 74926073	74884216 to 74912549	dup
26	57	19	40539029 to 40562762	40543992 to 40556205	del
26	58	19	58204170 to 58261341	58210642 to 58249435	del
26	59	19	59414645 to 59446274	59427018 to 59440274	h_del
26	60	21	46914686 to 15019428	14504218 to 14884298	dup
26	61	22	22671374 to 22736990	22677959 to 22731196	del
26	62	22	37683516 to 37718669	37689058 to 37715385	del
26	63	X	153127027 to 153158679	153158679 to 153158679	del
27	1	1	47276899 to 47344060	47288841 to 47305355	del
27	2	1	108661171 to 108727836	108680758 to 108701727	del
27	3	1	150819451 to 150861724	150823073 to 150857070	dup
27	4	1	151026228 to 151044659	151027357 to 151040463	dup
27	5	2	38801777 to 38835011	38810280 to 38829605	dup
27	6	3	89473678 to 89516057	89488409 to 89509246	dup
27	7	3	189887328 to 189915187	189892003 to 189908821	del
27	8	3	196656498 to 196933317	196904349 to 196929805	del
27	9	5	745859 to 848744	763494 to 837253	dup
27	10	6	78983276 to 79133892	79035891 to 79101978	dup
27	11	6	165640218 to 165664947	165645537 to 165657596	h_del
27	12	7	141408013 to 141453012	141413352 to 141452085	del
27	13	7	141687978 to 141720324	141705163 to 141711513	amp
27	14	7	153455702 to 153661525	153490741 to 153653779	dup
27	15	8	39341524 to 39535655	39356595 to 39511632	dup
27	16	9	107483547 to 107527507	107488651 to 107518386	del
27	17	10	47060942 to 47148030	47074824 to 47138700	dup
27	18	11	7762277 to 7803570	7774067 to 7797993	del
27	19	11	55118214 to 55207305	55124730 to 55200744	dup
27	20	13	56650373 to 56726008	56658479 to 56691355	dup
27	21	14	19268776 to 19380994	19273289 to 19362145	dup
27	22	14	19388122 to 19497023	19397709 to 19490630	dup
27	23	14	20191954 to 20215861	20194838 to 20210427	dup
27	24	14	20418299 to 20490129	20423918 to 20481680	dup
27	25	14	73071404 to 73114128	73075500 to 73106558	del
27	26	14	105594189 to 105654998	105602756 to 105643293	h_del
27	27	14	105857193 to 105898674	105863067 to 105881279	del
27	28	14	105946993 to 106002179	105962305 to 105994646	dup
27	29	15	18790589 to 19235401	18810004 to 19227549	dup
27	30	15	19281889 to 19786655	19291749 to 19537035	dup
27	31	15	19805960 to 19879661	19819961 to 19874690	dup
27	32	15	95606006 to 95668297	95616750 to 95658438	del
27	33	16	14876356 to 15023021	14956177 to 14997360	del
27	34	17	41515622 to 41558893	41521544 to 41553226	del
27	35	17	77478901 to 77535412	77503378 to 77519913	dup
27	36	20	1499034 to 1546858	1506379 to 1539155	h_del
27	37	X	62321946 to 62453817	62390645 to 62434259	del
27	38	X	118447421 to 118488821	118463317 to 118484359	dup
27	39	X	154037006 to 154050185	154050185 to 154050185	del
28	1	1	554268 to 736483	554287 to 639581	del
28	2	1	17104345 to 17157415	17114337 to 17148592	dup
28	3	1	25457903 to 25547799	25482036 to 25541997	dup
28	4	1	72533856 to 72602597	72550248 to 72568009	amp
28	5	1	147134175 to 147927292	147203277 to 147499046	dup
28	6	1	147946905 to 148081741	147965985 to 148035420	dup
28	7	1	150819451 to 150861724	150823073 to 150857070	dup
28	8	1	151026228 to 151044659	151027357 to 151040463	dup
28	9	1	159786265 to 159913146	159791446 to 159907508	dup
28	10	1	167483267 to 167538962	167493768 to 167523140	h_del
28	11	1	194978218 to 195033552	195005520 to 195026703	del
28	12	1	195045871 to 195091758	195048208 to 195067764	del
28	13	2	32480016 to 32557276	32496047 to 32548723	del
28	14	2	32564277 to 32628022	32572151 to 32616151	del
28	15	2	32640703 to 32891109	32652426 to 32878011	del
28	16	2	32907228 to 32991312	32916239 to 32975090	del
28	17	2	33080437 to 33173396	33093716 to 33167797	del
28	18	2	34539740 to 34608979	34556434 to 34580533	amp
28	19	2	87178812 to 87781651	87229588 to 87735976	dup
28	20	2	88924973 to 89207763	88932397 to 89145587	dup
28	21	2	89220538 to 89377632	89256456 to 89284248	dup
28	22	3	46761824 to 46841955	46771035 to 46829442	del
28	23	3	129842133 to 129903593	129851489 to 129883615	dup
28	24	4	68905670 to 69657500	69057735 to 69643272	h_del
28	25	5	802518 to 837253	812169 to 826044	del
28	26	5	37475302 to 37510190	37491462 to 37501489	amp
28	27	5	69274433 to 70622715	69741318 to 70422297	del
28	28	5	180194323 to 180379352	180342860 to 180365950	dup
28	29	6	32586131 to 32629848	32595402 to 32605300	del
28	30	6	32711957 to 32738443	32718991 to 32732764	del
28	31	6	35862502 to 35882448	35866245 to 35873335	amp
28	32	6	78983276 to 79133892	79035891 to 79101978	del
28	33	6	165640218 to 165664947	165645537 to 165657596	h_del
28	34	7	133414697 to 133465974	133439454 to 133459759	del
28	35	7	141408013 to 141453012	141413352 to 141452085	dup
28	36	7	141687978 to 141720324	141705163 to 141711513	amp
28	37	7	142152205 to 142178751	142159154 to 142178220	dup
28	38	7	143501811 to 143706194	143514962 to 143705425	del
28	39	8	7701787 to 8132139	7729311 to 8117271	dup
28	40	8	39341524 to 39535655	39356595 to 39511632	dup
28	41	8	85451657 to 85529191	85461490 to 85514517	dup
28	42	9	43165653 to 43599449	43445839 to 43550676	dup
28	43	11	55118214 to 55207305	55124730 to 55200744	dup
28	44	11	70513116 to 70534691	70519863 to 70530722	del
28	45	12	9452803 to 9626736	9528590 to 9613074	del
28	46	12	101817806 to 101992046	101875647 to 101932070	dup
28	47	14	19154992 to 19505698	19216369 to 19497023	dup
28	48	14	73060301 to 73106558	73071404 to 73104572	del
28	49	14	105308045 to 105384766	105314254 to 105379293	dup
28	50	14	105398979 to 105441874	105405952 to 105432521	dup
28	51	14	105447369 to 105680951	105455799 to 105672615	dup
28	52	14	105693581 to 105768318	105701420 to 105760541	dup
28	53	14	105776293 to 105863067	105787390 to 105857193	dup
28	54	14	105923159 to 106002179	105934843 to 105994646	dup
28	55	15	19819961 to 19963175	19833542 to 19952195	dup
28	56	15	19970687 to 20042671	19976279 to 20010559	dup
28	57	16	32208242 to 32545350	32378126 to 32534410	dup
28	58	16	33486907 to 33875313	33495501 to 33758082	dup
28	59	16	54390012 to 54444069	54400475 to 54437553	dup
28	60	16	68726557 to 68754234	68732367 to 68751390	del
28	61	16	72937352 to 73022578	72955519 to 73012768	del
28	62	17	41566540 to 41706870	41577520 to 41700762	dup
28	63	17	74872990 to 74926073	74884216 to 74912549	dup
28	64	18	65342290 to 65375155	65359770 to 65367911	amp
28	65	19	15632023 to 15703821	15640597 to 15698069	dup
28	66	19	48400983 to 48534223	48433091 to 48500241	del
28	67	19	56816785 to 56850433	56831724 to 56840346	amp
28	68	19	59414645 to 59440274	59427018 to 59434159	amp
28	69	22	22671374 to 22736990	22677959 to 22731196	del
28	70	22	32073084 to 32081586	32081586 to 32081586	del
29	1	1	12793618 to 12841351	12822189 to 12840011	del
29	2	1	16900526 to 16960984	16911911 to 16926444	del
29	3	1	72533856 to 72652073	72550248 to 72602597	h_del
29	4	1	194978218 to 195062024	195005520 to 195048208	dup
29	5	2	34539740 to 34627348	34556434 to 34608979	h_del
29	6	2	88984458 to 89220538	88995175 to 89207763	dup
29	7	2	227946001 to 227990692	227952131 to 227973265	dup
29	8	2	242565932 to 242602220	242572731 to 242596654	del
29	9	2	242608960 to 242628911	242622792 to 242622792	del
29	10	2	242637386 to 242700979	242646987 to 242689978	del
29	11	3	196656498 to 196929805	196904349 to 196924340	dup
29	12	4	70184190 to 70299545	70188454 to 70296172	dup
29	13	5	140196482 to 140228321	140203440 to 140221835	dup
29	14	5	180194323 to 180365950	180342860 to 180362342	del
29	15	6	174815 to 262620	204528 to 252939	dup
29	16	6	273710 to 320890	284743 to 314420	dup
29	17	6	29950805 to 30026699	29962849 to 30021894	del
29	18	6	165640218 to 165657596	165645537 to 165650610	amp
29	19	7	141408013 to 141453012	141413352 to 141452085	del
29	20	7	141687978 to 141720324	141705163 to 141711513	amp
29	21	7	142152205 to 142178751	142159154 to 142178220	dup
29	22	7	143501811 to 143706194	143514962 to 143705425	dup
29	23	8	15437205 to 15475696	15447810 to 15466032	del
29	24	8	71762853 to 71820190	71779510 to 71807546	del
29	25	9	112060652 to 112086263	112064860 to 112074405	del
29	26	10	53627094 to 53675784	53638368 to 53669383	del
29	27	10	100670683 to 100700712	100678817 to 100695568	del
29	28	11	5738494 to 5777496	5742476 to 5766615	del
29	29	11	31074603 to 31667093	31081786 to 31661652	del
29	30	11	55118214 to 55200744	55124730 to 55194990	del
29	31	14	19456276 to 19461971	19459171 to 19459171	del
29	32	14	19467512 to 19497023	19473780 to 19490630	del
29	33	14	40670538 to 40746865	40704122 to 40726930	amp
29	34	14	73060301 to 73106558	73071404 to 73104572	dup
29	35	14	105398979 to 105441874	105405952 to 105432521	dup
29	36	14	105469325 to 105515561	105476748 to 105504747	dup
29	37	14	105536949 to 105584008	105545545 to 105576121	dup
29	38	14	105594189 to 105654998	105602756 to 105643293	del
29	39	14	105857193 to 105898674	105863067 to 105881279	del
29	40	14	106216726 to 106268973	106223137 to 106260876	del
29	41	15	32511475 to 32544263	32517513 to 32536263	dup
29	42	15	32553674 to 32594902	32563500 to 32590643	dup
29	43	16	2605126 to 2649851	2638581 to 2645485	del
29	44	16	32378126 to 32745412	32481309 to 32561819	dup
29	45	16	33280759 to 33316641	33288352 to 33300400	dup
29	46	16	33486907 to 33539023	33495501 to 33533440	dup
29	47	16	34297461 to 34685270	34339543 to 34634686	dup
29	48	16	54390012 to 54444069	54400475 to 54437553	dup
29	49	17	31456645 to 31889297	31461588 to 31504564	dup
29	50	17	41515622 to 41566540	41521544 to 41558893	del
29	51	19	3875484 to 3911050	3886180 to 3902577	del
29	52	19	40539029 to 40562762	40543992 to 40556205	del
29	53	19	46032440 to 46078903	46042726 to 46073325	dup
29	54	20	1506379 to 1557784	1516966 to 1546858	dup
29	55	20	14722913 to 14786217	14729413 to 14777904	dup
29	56	22	22681995 to 22686690	22686690 to 22686690	del
30	1	1	25457903 to 25541997	25482036 to 25536086	dup
30	2	1	146375659 to 147927292	147134175 to 147499046	dup
30	3	1	159791446 to 159900223	159876777 to 159895967	dup
30	4	1	246755225 to 246890704	246794522 to 246880850	dup
30	5	2	32548723 to 32596907	32557276 to 32588320	del
30	6	2	32696811 to 32907228	32697011 to 32891109	del
30	7	2	32916239 to 32975090	32927818 to 32958034	del
30	8	2	32991312 to 33017315	32998706 to 33008263	del
30	9	2	33030410 to 33062778	33041064 to 33054999	del
30	10	2	33071907 to 33148227	33080437 to 33139801	del
30	11	2	87178812 to 87661927	87229588 to 87613207	dup
30	12	2	88924973 to 89256456	88932397 to 89220538	dup
30	13	3	120200987 to 120307534	120209074 to 120306710	dup
30	14	3	163987457 to 164123806	163997228 to 164112873	dup
30	15	3	196904349 to 196929805	196911055 to 196924340	del
30	16	4	68905670 to 69657500	69057735 to 69643272	del
30	17	5	739292 to 848744	745859 to 837253	del
30	18	5	859176 to 905462	873416 to 894957	del
30	19	5	180194323 to 180379352	180342860 to 180365950	dup
30	20	6	32507380 to 32629848	32519935 to 32605300	dup
30	21	6	165640218 to 165664947	165645537 to 165657596	del
30	22	7	38270942 to 38312900	38276237 to 38305379	del
30	23	7	133414697 to 133465974	133439454 to 133459759	h_del
30	24	7	141408013 to 141453012	141413352 to 141452085	h_del
30	25	7	141687978 to 141720324	141705163 to 141711513	amp
30	26	7	142164247 to 142178220	142167901 to 142171618	amp
30	27	8	7256229 to 7747772	7261418 to 7729311	dup
30	28	8	11903901 to 12511855	12077339 to 12448374	dup
30	29	8	15982454 to 16079852	15996382 to 16070654	del
30	30	8	33264004 to 33344787	33306169 to 33337952	dup
30	31	8	33348916 to 33476716	33354628 to 33473611	dup
30	32	8	33483345 to 33552728	33490000 to 33548384	dup
30	33	9	112060652 to 112086263	112064860 to 112074405	del
30	34	9	138784969 to 138806983	138791196 to 138805207	del
30	35	10	45534651 to 46408696	45554717 to 46404919	dup
30	36	11	7762277 to 7803570	7774067 to 7797993	del
30	37	11	55112329 to 55207305	55118214 to 55200744	dup
30	38	12	9452803 to 9626736	9528590 to 9613074	del
30	39	12	82862371 to 82996016	82881625 to 82950135	del
30	40	14	19268776 to 19330937	19273289 to 19323579	dup
30	41	14	19350230 to 19505698	19362145 to 19497023	dup
30	42	14	21920051 to 21981288	21931667 to 21973343	del
30	43	14	21993784 to 22046097	22000194 to 22034704	del
30	44	14	105398979 to 105447369	105405952 to 105441874	dup
30	45	14	105536949 to 105643293	105545545 to 105630089	dup
30	46	14	105654998 to 105857193	105672615 to 105845658	dup
30	47	14	105863067 to 105934843	105873009 to 105923159	dup
30	48	14	105946993 to 105994646	105962305 to 105985458	dup
30	49	14	106002179 to 106056612	106017453 to 106048712	dup
30	50	16	3143106 to 3195143	3159477 to 3186299	dup
30	51	16	32378126 to 32553402	32481309 to 32545350	dup
30	52	16	33486907 to 33533440	33495501 to 33527454	dup
30	53	16	72937352 to 73022578	72955519 to 73012768	del
30	54	17	31456645 to 31889297	31461588 to 31504564	del
30	55	18	65342290 to 65375155	65359770 to 65367911	amp
30	56	19	56816785 to 56850433	56831724 to 56840346	amp
30	57	19	59414645 to 59446274	59427018 to 59440274	del
30	58	19	59487170 to 59507350	59492650 to 59502178	del
30	59	22	21169644 to 21199700	21173465 to 21196638	dup
30	60	22	21264394 to 21342013	21277813 to 21337368	dup
30	61	22	21386562 to 21409281	21398764 to 21404393	dup
30	62	22	21417094 to 21452488	21427178 to 21443735	dup
30	63	22	21460395 to 21588229	21470618 to 21575829	dup
30	64	22	22671374 to 22736990	22677959 to 22731196	dup
30	65	X	62321946 to 62453817	62390645 to 62434259	h_del
30	66	X	153127027 to 153158679	153158679 to 153158679	amp
31	1	1	17094475 to 17148592	17104345 to 17130528	dup
31	2	1	25457903 to 25547799	25482036 to 25541997	dup
31	3	1	72533856 to 72652073	72550248 to 72602597	del
31	4	1	151026228 to 151044659	151027357 to 151040463	del
31	5	1	246794522 to 246805521	246795223 to 246795223	del
31	6	1	246812523 to 246880850	246822838 to 246874992	del
31	7	2	34539740 to 34627348	34556434 to 34608979	del
31	8	2	81363444 to 81481628	81386092 to 81453471	del
31	9	2	88924973 to 89263354	88932397 to 89256456	del
31	10	2	187714155 to 187867949	187758371 to 187832894	del
31	11	3	164023502 to 164123806	164038917 to 164112873	h_del
31	12	3	199228720 to 199266105	199235950 to 199251129	del
31	13	3	199288161 to 199329592	199300213 to 199321387	del
31	14	4	68905670 to 69657500	69057735 to 69643272	del
31	15	4	70201666 to 70264689	70207135 to 70255674	del
31	16	5	745859 to 848744	763494 to 837253	del
31	17	5	859176 to 905462	873416 to 894957	del
31	18	5	17570523 to 17685501	17647063 to 17674967	del
31	19	5	32133136 to 32217543	32146491 to 32209048	dup
31	20	5	37475302 to 37510190	37491462 to 37501489	amp
31	21	5	69767948 to 70622715	70343857 to 70422297	del
31	22	5	140196482 to 140228321	140203440 to 140221835	dup
31	23	5	150166447 to 150224239	150185190 to 150209789	del
31	24	5	175563657 to 175648882	175590732 to 175600582	amp
31	25	5	180342860 to 180365950	180351118 to 180362342	del
31	26	6	174815 to 262620	204528 to 252939	dup
31	27	6	29975388 to 30021894	29981930 to 30010234	del
31	28	6	32702995 to 32738443	32711957 to 32732764	dup
31	29	6	78983276 to 79133892	79035891 to 79101978	h_del
31	30	7	141408013 to 141453012	141413352 to 141452085	h_del
31	31	8	6929691 to 8132139	7040596 to 8117271	dup
31	32	8	39341524 to 39535655	39356595 to 39511632	dup
31	33	9	17568661 to 17626610	17585185 to 17620872	dup
31	34	9	112060652 to 112086263	112064860 to 112074405	del
31	35	10	46404919 to 46427571	46408696 to 46423080	del
31	36	10	46431590 to 47025997	46444985 to 47010385	del
31	37	10	47138700 to 47172534	47148030 to 47161232	del
31	38	10	89148059 to 89241227	89178988 to 89199763	amp
31	39	11	18896166 to 18929375	18906505 to 18915871	amp
31	40	11	55118214 to 55207305	55124730 to 55200744	dup
31	41	12	9452803 to 9626736	9528590 to 9613074	h_del
31	42	12	84421489 to 84607143	84437166 to 84582421	dup
31	43	14	19154992 to 19505698	19216369 to 19497023	dup
31	44	14	40670538 to 40779816	40704122 to 40746865	del
31	45	14	105398979 to 105515561	105405952 to 105504747	h_del
31	46	14	105536949 to 105654998	105545545 to 105643293	h_del
31	47	14	105845658 to 105898674	105857193 to 105881279	del
31	48	14	105946993 to 105994646	105962305 to 105985458	del
31	49	14	106216726 to 106260876	106223137 to 106251081	del
31	50	15	18790589 to 19121757	18810004 to 19109124	dup
31	51	15	19786655 to 19952195	19805960 to 19943194	dup
31	52	15	19963175 to 20307869	19970687 to 20249886	dup
31	53	15	30232492 to 30686791	30249934 to 30648859	dup
31	54	15	41729085 to 41803782	41737960 to 41782489	del
31	55	15	95606006 to 95668297	95616750 to 95658438	del
31	56	16	68710277 to 68838368	68726557 to 68795079	dup
31	57	16	72917554 to 73022578	72933295 to 73012768	dup
31	58	17	40901702 to 41062669	40926154 to 41041674	dup
31	59	17	41566540 to 41635536	41577520 to 41624471	dup
31	60	17	41644979 to 42049540	41700762 to 41983407	dup
31	61	22	22681995 to 22686690	22686690 to 22686690	dup
32	1	1	25457903 to 25541997	25482036 to 25536086	dup
32	2	1	72533856 to 72602597	72550248 to 72568009	amp
32	3	1	147213294 to 147987813	147307637 to 147978622	dup
32	4	1	167483267 to 167523140	167493768 to 167507882	amp
32	5	1	195045871 to 195187023	195048208 to 195165228	dup
32	6	3	89473678 to 89499433	89488409 to 89493682	del
32	7	3	164023502 to 164101776	164038917 to 164086905	del
32	8	3	196933317 to 196968244	196942158 to 196958467	dup
32	9	4	70159690 to 70296172	70184190 to 70264689	dup
32	10	4	132507641 to 132550171	132519648 to 132536630	amp
32	11	5	745859 to 837253	763494 to 826044	h_del
32	12	5	37043865 to 37109511	37051902 to 37096717	dup
32	13	5	69274433 to 70343857	69741318 to 69767948	h_del
32	14	5	140196482 to 1572735	140203440 to 1567217	dup
32	15	6	161732311 to 161776261	161750297 to 161768616	del
32	16	7	141408013 to 141438504	141413352 to 141431668	del
32	17	7	141687978 to 141720324	141705163 to 141711513	h_del
32	18	7	142164247 to 142178220	142167901 to 142171618	h_del
32	19	11	55118214 to 55200744	55124730 to 55194990	dup
32	20	14	105594189 to 105643293	105602756 to 105630089	h_del
32	21	14	105845658 to 105898674	105857193 to 105881279	dup
32	22	15	20079935 to 20800736	20220416 to 20773131	dup
32	23	15	32517513 to 32578483	32523241 to 32572315	del
32	24	17	41515622 to 41577520	41521544 to 41566540	dup
32	25	22	18691941 to 19063427	18989547 to 19038890	amp
32	26	22	22644243 to 22658543	22656831 to 22656831	amp
32	27	22	22671374 to 22731196	22677959 to 22725305	del
32	28	22	37683516 to 37718669	37689058 to 37715385	dup
32	29	X	62321946 to 62390645	62390645 to 62390645	h_del
33	1	1	554268 to 736483	554287 to 639581
33	2	1	17086698 to 17124554	17088704 to 17114337	dup
33	3	1	25457903 to 25541997	25482036 to 25536086	h_del
33	4	1	72533856 to 72652073	72550248 to 72602597	h_del
33	5	1	110017502 to 110062339	110023268 to 110057882	dup
33	6	1	150819451 to 150861724	150823073 to 150857070	del
33	7	1	151026228 to 151044659	151027357 to 151040463	del
33	8	1	167483267 to 167538962	167493768 to 167523140	del
33	9	1	194978218 to 195104207	195005520 to 195091758	dup
33	10	1	246683018 to 246713357	246688566 to 246711305	dup
33	11	1	246755225 to 246805521	246794522 to 246795223	del
33	12	1	246812523 to 246880850	246822838 to 246874992	del
33	13	2	32480016 to 33071907	32496047 to 33062778	dup
33	14	2	33080437 to 33139801	33093716 to 33128874	dup
33	15	2	33148227 to 33205267	33156634 to 33189314	dup
33	16	2	34539740 to 34627348	34556434 to 34608979	h_del
33	17	2	88932397 to 89093646	88944977 to 89078609	del
33	18	2	89408826 to 89755931	89654638 to 89750144	dup
33	19	2	89856321 to 90982930	89863711 to 89895566	dup
33	20	2	111843508 to 111952139	111891528 to 111932907	del
33	21	3	174721900 to 174785195	174736125 to 174775059	dup
33	22	4	68905670 to 69657500	69057735 to 69643272	dup
33	23	5	725942 to 905462	739292 to 894957	dup
33	24	5	37475302 to 37515693	37491462 to 37510190	h_del
33	25	5	140196482 to 140228321	140203440 to 140221835	dup
33	26	5	175563657 to 175657218	175590732 to 175648882	h_del
33	27	5	180342860 to 180379352	180351118 to 180365950	h_del
33	28	6	174815 to 262620	204528 to 252939	del
33	29	6	29802169 to 29840973	29808111 to 29833986	dup
33	30	6	29950805 to 30026699	29962849 to 30021894	dup
33	31	6	32600962 to 32634044	32605300 to 32629848	amp
33	32	6	32702995 to 32738443	32711957 to 32732764	dup
33	33	6	35862502 to 35887585	35866245 to 35882448	del
33	34	7	32185898 to 32229880	32193044 to 32224735	del
33	35	7	32254133 to 32300981	32269032 to 32294558	del
33	36	7	32313688 to 32423824	32327287 to 32383491	del
33	37	7	100162851 to 100194979	100171204 to 100183859	del
33	38	7	141408013 to 141453012	141413352 to 141452085	del
33	39	7	141687978 to 141727147	141705163 to 141720324	h_del
33	40	7	142152205 to 142178751	142159154 to 142178220	del
33	41	7	143501811 to 143706194	143514962 to 143705425	dup
33	42	8	7701787 to 8117271	7729311 to 7789937	h_del
33	43	8	39341524 to 39464577	39356595 to 39457650	del
33	44	8	39470226 to 39535655	39475979 to 39511632	del
33	45	8	43254441 to 43309920	43264404 to 43291237	del
33	46	8	43345026 to 43452736	43353214 to 43419507	del
33	47	9	83721179 to 83788611	83754779 to 83784529	dup
33	48	10	46371243 to 46423080	46384979 to 46414875	del
33	49	10	46462545 to 46506743	46473500 to 46500053	del
33	50	10	46512806 to 47010385	46516583 to 46568496	del
33	51	10	47074824 to 47133281	47089737 to 47125093	del
33	52	10	47138700 to 47735472	47148030 to 47172534	del
33	53	10	89148059 to 89253592	89178988 to 89241227	h_del
33	54	11	55118214 to 55207305	55124730 to 55200744	h_del
33	55	12	9452803 to 9633884	9528590 to 9626736	dup
33	56	13	56650373 to 56726008	56658479 to 56691355	dup
33	57	14	105398979 to 105447369	105405952 to 105441874	h_del
33	58	14	105536949 to 105568190	105545545 to 105556724	del
33	59	14	105576121 to 105643293	105584008 to 105630089	del
33	60	14	105701420 to 105776293	105708209 to 105768318	del
33	61	14	105946993 to 106002179	105962305 to 105994646	dup
33	62	14	106216726 to 106260876	106223137 to 106251081	del
33	63	15	19427350 to 19805960	19435500 to 19786655	del
33	64	15	30298096 to 30686791	30405629 to 30648859	del
33	65	16	3143106 to 3186299	3159477 to 3177627	del
33	66	16	18577167 to 18701947	18599499 to 18701570	del
33	67	16	31862577 to 32105104	31958973 to 32004586	del
33	68	16	33486907 to 33875313	33495501 to 33758082	del
33	69	17	31456645 to 31891535	31461588 to 31889297	dup
33	70	18	65342290 to 65385582	65359770 to 65375155	h_del
33	71	19	56816785 to 56859204	56831724 to 56850433	h_del
33	72	X	62321946 to 62434259	62390645 to 62416396	amp
33	73	X	153067477 to 153186834	153127027 to 153176364	del
33	74	X	154561606 to 154570177	154570177 to 154570177	dup
34	1	1	116950996 to 117008723	116970390 to 117001475	dup
34	2	1	147213294 to 147946905	147307637 to 147927292	h_del
34	3	1	151026228 to 151044659	151027357 to 151040463	dup
34	4	1	159750339 to 159786265	159758730 to 159778722	dup
34	5	1	16807713 to 16893620	16820714 to 16884678	dup
34	6	1	16921319 to 17086698	16926444 to 17082119	dup
34	7	1	246683018 to 246750352	246688566 to 246713357	dup
34	8	1	246755225 to 246805521	246794522 to 246795223	del
34	9	1	246812523 to 246880850	246822838 to 246874992	h_del
34	10	1	72533856 to 72652073	72550248 to 72602597	h_del
34	11	11	95842634 to 95963703	95855890 to 95946296	dup
34	12	12	10465787 to 10497371	10474925 to 10493984	del
34	13	12	7884886 to 7956956	7894681 to 7944668	dup
34	14	12	7963159 to 8056718	7969578 to 8036400	dup
34	15	12	9452803 to 9633884	9528590 to 9626736	h_del
34	16	13	42629858 to 42696134	42663797 to 42691461	dup
34	17	14	105594189 to 105643293	105602756 to 105630089	del
34	18	14	105946993 to 106002179	105962305 to 105994646	dup
34	19	14	106216726 to 106260876	106223137 to 106251081	del
34	20	14	18187154 to 18864561	18504575 to 18642252	del
34	21	14	19216369 to 19350230	19268776 to 19330937	dup
34	22	14	19388122 to 19505698	19397709 to 19497023	dup
34	23	14	73060301 to 73104572	73071404 to 73092018	del
34	24	15	19874690 to 19910867	19879661 to 19886840	del
34	25	15	28606757 to 28748125	28719136 to 28742018	del
34	26	16	31862577 to 32105104	31958973 to 32004586	del
34	27	16	32378126 to 32561819	32481309 to 32553402	del
34	28	16	33288352 to 33316641	33289608 to 33300400	del
34	29	16	33486907 to 33875313	33495501 to 33758082	del
34	30	16	34297461 to 34584793	34339543 to 34539890	del
34	31	16	54390012 to 54437553	54400475 to 54422612	dup
34	32	16	87739826 to 87817666	87744023 to 87813045	dup
34	33	17	41515622 to 41577520	41521544 to 41566540	dup
34	34	17	41587723 to 41700762	41599011 to 41644979	dup
34	35	19	59487170 to 59507350	59492650 to 59502178	del
34	36	2	242393213 to 242602220	242565932 to 242596654	dup
34	37	2	242608960 to 242700979	242622792 to 242689978	dup
34	38	2	34539740 to 34627348	34556434 to 34608979	del
34	39	2	89408826 to 89755931	89654638 to 89750144	del
34	40	2	89856321 to 90982930	89863711 to 89895566	del
34	41	20	1499034 to 1539155	1506379 to 1528899	del
34	42	22	33086125 to 33291150	33121333 to 33242946	del
34	43	3	164023502 to 164123806	164038917 to 164112873	dup
34	44	3	196656498 to 196943380	196904349 to 196942158	del
34	45	3	75845446 to 75914406	75858339 to 75896020	dup
34	46	4	68511739 to 68586205	68530854 to 68578670	dup
34	47	4	70207135 to 70264689	70216707 to 70255674	del
34	48	5	180342860 to 180379352	180351118 to 180365950	del
34	49	5	37475302 to 37515693	37491462 to 37510190	del
34	50	5	802518 to 826044	812169 to 819038	del
34	51	5	837253 to 878290	848744 to 873416	del
34	52	6	160948812 to 161001748	160951944 to 160991636	del
34	53	6	174815 to 262620	204528 to 252939	del
34	54	6	31377756 to 31425144	31385778 to 31418006	del
34	55	6	32519935 to 32629848	32558677 to 32605300	del
34	56	6	32634044 to 32683958	32654432 to 32672983	del
34	57	6	78983276 to 79133892	79035891 to 79101978	h_del
34	58	7	100162851 to 100194979	100171204 to 100183859	h_del
34	59	7	128766157 to 128801493	128775509 to 128789921	del
34	60	7	141408013 to 141453012	141413352 to 141452085	dup
34	61	7	141687978 to 141727147	141705163 to 141720324	h_del
34	62	7	142164247 to 142178751	142167901 to 142178220	del
34	63	8	12077339 to 12548003	12276178 to 12511855	dup
34	64	9	134932959 to 134938349	134938349 to 134938349	dup
35	1	1	16900526 to 17086698	16911911 to 17082119	dup
35	2	1	72533856 to 72652073	72550248 to 72602597	h_del
35	3	1	147213294 to 147386918	147307637 to 147357754	del
35	4	1	150819451 to 150861724	150823073 to 150857070	h_del
35	5	1	246755225 to 246805521	246794522 to 246795223	del
35	6	1	246812523 to 246880850	246822838 to 246874992	del
35	7	2	88932397 to 88984458	88944977 to 88971719	dup
35	8	2	132117324 to 132206366	132130850 to 132185414	dup
35	9	2	242393213 to 242602220	242565932 to 242596654	del
35	10	2	242608960 to 242700979	242622792 to 242689978	h_del
35	11	3	163987457 to 164123806	163997228 to 164112873	del
35	12	3	196933317 to 196978235	196942158 to 196968244	dup
35	13	4	68905670 to 69657500	69057735 to 69643272	dup
35	14	4	70130975 to 70299545	70159690 to 70296172	dup
35	15	4	79011907 to 79049463	79023641 to 79040612	del
35	16	5	28961655 to 29188493	28971597 to 29166378	del
35	17	5	32133136 to 32217543	32146491 to 32209048	dup
35	18	5	37475302 to 37510190	37491462 to 37501489	amp
35	19	5	140196482 to 140228321	140203440 to 140221835	del
35	20	5	175563657 to 175648882	175590732 to 175600582	amp
35	21	5	180194323 to 180379352	180342860 to 180365950	dup
35	22	6	174815 to 262620	204528 to 252939	dup
35	23	6	32519935 to 32629848	32558677 to 32605300	dup
35	24	6	78983276 to 79133892	79035891 to 79101978	h_del
35	25	7	38277728 to 38296218	38281765 to 38290450	del
35	26	7	141408013 to 141453012	141413352 to 141452085	dup
35	27	8	12077339 to 12448374	12276178 to 12285464	amp
35	28	8	13476994 to 13580299	13483725 to 13543130	dup
35	29	9	1767483 to 1817515	1783496 to 1808052	del
35	30	11	7762277 to 7803570	7774067 to 7797993	dup
35	31	11	55118214 to 55207305	55124730 to 55200744	dup
35	32	11	89400624 to 89496302	89413821 to 89482692	dup
35	33	12	81689864 to 81748190	81702107 to 81740575	del
35	34	13	56650373 to 56726008	56658479 to 56691355	del
35	35	14	18537177 to 19505698	18624383 to 19497023	dup
35	36	14	21958644 to 21993784	21966870 to 21981288	del
35	37	14	73071404 to 73104572	73075500 to 73092018	del
35	38	14	105398979 to 105455799	105405952 to 105447369	dup
35	39	14	105643293 to 105701420	105654998 to 105693581	dup
35	40	14	105708209 to 105812803	105724107 to 105799261	dup
35	41	14	106216726 to 106268973	106223137 to 106260876	dup
35	42	15	19537035 to 19860116	19786655 to 19845942	del
35	43	15	19927262 to 19963175	19933992 to 19952195	del
35	44	15	22163893 to 22346355	22232458 to 22329016	dup
35	45	16	2592859 to 2649851	2605126 to 2645485	del
35	46	16	18069609 to 18701947	18205105 to 18701570	dup
35	47	16	32004586 to 32748349	32105104 to 32745412	dup
35	48	16	33316641 to 33433058	33373002 to 33424939	dup
35	49	16	33445329 to 33875313	33472086 to 33758082	dup
35	50	16	34297461 to 34685270	34339543 to 34634686	dup
35	51	16	54343465 to 54400475	54354643 to 54390012	dup
35	52	19	20383210 to 20523656	20422576 to 20510787	del
35	53	19	40539029 to 40556205	40543992 to 40548081	amp
35	54	19	62679393 to 62702260	62682738 to 62697513	dup
35	55	20	14277060 to 14343797	14285858 to 14335648	dup
35	56	22	37683516 to 37689058	37689058 to 37689058	dup
36	1	1	1160181 to 1196747	1165696 to 1188225	dup
36	2	1	16921319 to 17086698	16926444 to 17082119	del
36	3	1	25457903 to 25547799	25482036 to 25541997	dup
36	4	1	72533856 to 72602597	72550248 to 72568009	amp
36	5	1	110017502 to 110062339	110023268 to 110057882	del
36	6	1	116950996 to 117008723	116970390 to 117001475	dup
36	7	1	147203277 to 147987813	147213294 to 147978622	dup
36	8	1	150819451 to 150866947	150823073 to 150861724	dup
36	9	1	151026228 to 151044659	151027357 to 151040463	dup
36	10	1	191336918 to 191377619	191341540 to 191371193	dup
36	11	1	246683018 to 246711305	246688566 to 246702361	del
36	12	1	246812523 to 246890704	246822838 to 246880850	dup
36	13	2	32513992 to 32596907	32519984 to 32588320	del
36	14	2	32608307 to 32640703	32616151 to 32628022	del
36	15	2	32652426 to 32750852	32659456 to 32742980	del
36	16	2	32757415 to 32790864	32763943 to 32781516	del
36	17	2	32799455 to 32856392	32812404 to 32847049	del
36	18	2	32865684 to 32891109	32871072 to 32878011	del
36	19	2	32907228 to 33008263	32916239 to 32998706	del
36	20	2	33030410 to 33062778	33041064 to 33054999	del
36	21	2	33071907 to 33110959	33080437 to 33102581	del
36	22	2	33121271 to 33156634	33128874 to 33148227	del
36	23	2	34539740 to 34608979	34556434 to 34580533	amp
36	24	2	87178812 to 87786474	87229588 to 87781651	dup
36	25	2	88924973 to 89220538	88932397 to 89207763	dup
36	26	2	112193136 to 112342911	112206769 to 112338434	dup
36	27	3	163987457 to 164123806	163997228 to 164112873	dup
36	28	5	802518 to 826044	812169 to 819038	del
36	29	5	837253 to 905462	848744 to 894957	del
36	30	5	37475302 to 37510190	37491462 to 37501489	amp
36	31	5	140526960 to 140550615	140533456 to 140545963	dup
36	32	5	180194323 to 180379352	180342860 to 180365950	dup
36	33	6	174815 to 262620	204528 to 252939	dup
36	34	6	29950805 to 30026699	29962849 to 30021894	dup
36	35	6	78983276 to 79133892	79035891 to 79101978	del
36	36	6	165640218 to 165664947	165645537 to 165657596	del
36	37	7	892695 to 933785	897068 to 922544	dup
36	38	7	133414697 to 133465974	133439454 to 133459759	h_del
36	39	7	141402937 to 141453012	141408013 to 141452085	dup
36	40	7	141687978 to 141720324	141705163 to 141711513	amp
36	41	7	142152205 to 142178751	142159154 to 142178220	dup
36	42	7	143514962 to 143705425	143582864 to 143584350	del
36	43	8	7701787 to 8132139	7729311 to 8117271	dup
36	44	8	145062148 to 145101628	145067179 to 145091748	dup
36	45	9	112060652 to 112086263	112064860 to 112074405	del
36	46	9	138361990 to 138390698	138369981 to 138387485	dup
36	47	10	76818526 to 76854355	76828065 to 76844480	dup
36	48	11	5738494 to 5777496	5742476 to 5766615	dup
36	49	11	55118214 to 55207305	55124730 to 55200744	dup
36	50	12	101817806 to 101992046	101875647 to 101932070	dup
36	51	14	18537177 to 19505698	18624383 to 19497023	dup
36	52	14	40670538 to 40779816	40704122 to 40746865	del
36	53	14	69078818 to 69106345	69088190 to 69098569	del
36	54	14	73060301 to 73106558	73071404 to 73104572	del
36	55	14	105082760 to 105178535	105105322 to 105169640	dup
36	56	14	105280523 to 105314254	105286479 to 105308045	dup
36	57	14	105322191 to 105369044	105330913 to 105361835	dup
36	58	14	105398979 to 105584008	105405952 to 105576121	dup
36	59	14	105594189 to 105654998	105602756 to 105643293	h_del
36	60	14	105693581 to 105923159	105701420 to 105907191	dup
36	61	15	19786655 to 19879661	19805960 to 19874690	dup
36	62	15	19882711 to 20307869	19886840 to 20249886	dup
36	63	16	511780 to 557428	524396 to 552637	dup
36	64	16	613201 to 654002	621556 to 650166	dup
36	65	16	1478848 to 1514105	1482640 to 1502609	dup
36	66	16	11243506 to 11269436	11251386 to 11263596	dup
36	67	16	32378126 to 32553402	32481309 to 32545350	dup
36	68	16	65739934 to 65759425	65747201 to 65755542	dup
36	69	17	41566540 to 41841187	41577520 to 41706870	dup
36	70	17	75376816 to 75407306	75380512 to 75399375	dup
36	71	18	65342290 to 65375155	65359770 to 65367911	amp
36	72	19	509633 to 551018	521823 to 544916	dup
36	73	19	1384778 to 1419448	1390151 to 1413309	dup
36	74	19	2166856 to 2198406	2173267 to 2191758	dup
36	75	19	40539029 to 40562762	40543992 to 40556205	del
36	76	19	56816785 to 56850433	56831724 to 56840346	amp
36	77	20	61640278 to 61669839	61643034 to 61663726	dup
36	78	20	62134857 to 62161541	62139491 to 62156028	dup
36	79	21	46239917 to 46263844	46244682 to 46256922	dup
36	80	22	22671374 to 22736990	22677959 to 22731196	del
36	81	X	62321946 to 62453817	62390645 to 62434259	h_del
36	82	X	153127027 to 153158679	153158679 to 153158679	amp
37	1	1	47276899 to 47344060	47288841 to 47305355	del
37	2	1	103899771 to 103965274	103909053 to 103965227	dup
37	3	1	143700072 to 143793179	143706304 to 143787504	dup
37	4	1	150819451 to 150861724	150823073 to 150857070	dup
37	5	1	151026228 to 151044659	151027357 to 151040463	dup
37	6	2	43372667 to 43413230	43381945 to 43401068	del
37	7	2	130410455 to 130453313	130427905 to 130447827	dup
37	8	2	132093699 to 132210342	132117324 to 132206366	dup
37	9	2	242565932 to 242622792	242572731 to 242608960	del
37	10	2	242637386 to 242700979	242646987 to 242689978	del
37	11	3	89473678 to 89516057	89488409 to 89509246	dup
37	12	3	163987457 to 164123806	163997228 to 164112873	dup
37	13	4	70184190 to 70299545	70188454 to 70296172	dup
37	14	5	104145969 to 104337899	104170279 to 104327699	del
37	15	5	150166447 to 150224239	150185190 to 150209789	del
37	16	6	32558677 to 32654432	32567382 to 32634044	h_del
37	17	6	165640218 to 165664947	165645537 to 165657596	h_del
37	18	7	141408013 to 141453012	141413352 to 141452085	del
37	19	7	141687978 to 141720324	141705163 to 141711513	amp
37	20	7	143514962 to 143706194	143582864 to 143705425	dup
37	21	7	153455702 to 153661525	153490741 to 153653779	dup
37	22	8	7040596 to 7747772	7256229 to 7729311	dup
37	23	8	12077339 to 12448374	12276178 to 12285464	amp
37	24	8	39341524 to 39535655	39356595 to 39511632	dup
37	25	9	43165653 to 43550676	43445839 to 43530076	del
37	26	9	112060652 to 112086263	112064860 to 112074405	del
37	27	10	56112067 to 56142414	56122417 to 56135384	del
37	28	11	5738494 to 5777496	5742476 to 5766615	del
37	29	11	55118214 to 55207305	55124730 to 55200744	dup
37	30	12	9452803 to 9626736	9528590 to 9613074	h_del
37	31	12	31173065 to 31257959	31226529 to 31248212	del
37	32	13	56650373 to 56726008	56658479 to 56691355	dup
37	33	14	18537177 to 19154992	18624383 to 19090564	dup
37	34	14	19273289 to 19350230	19284254 to 19330937	dup
37	35	14	19362145 to 19505698	19380994 to 19497023	dup
37	36	14	73060301 to 73106558	73071404 to 73104572	h_del
37	37	14	105594189 to 105654998	105602756 to 105643293	h_del
37	38	14	105857193 to 105898674	105863067 to 105881279	del
37	39	14	105946993 to 106002179	105962305 to 105994646	dup
37	40	15	18874663 to 19235401	18884436 to 19227549	dup
37	41	15	19338183 to 19786655	19347444 to 19537035	dup
37	42	16	21448093 to 21507188	21476688 to 21501073	dup
37	43	20	1499034 to 1546858	1506379 to 1539155	del
37	44	21	46914686 to 15019428	14504218 to 14884298	dup
37	45	22	22671374 to 22736990	22677959 to 22731196	dup
37	46	X	62321946 to 62453817	62390645 to 62434259	del
37	47	X	118447421 to 118463317	118463317 to 118463317	dup

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Tags: American Journal of Ophthalmology Volume 151 Issue 6

Jan 16, 2017 | Posted by drzezo in OPHTHALMOLOGY | Comments Off

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Fastest Otolaryngology & Ophthalmology Insight Engine

High Frequency Of Submicroscopic Chromosomal Deletions in Patients with Idiopathic Congenital Eye Malformations

Purpose

Design

Methods

Results

Conclusions

Methods

Agilent Array Comparative Genomic Hybridization

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Ento Key

Fastest Otolaryngology & Ophthalmology Insight Engine

High Frequency Of Submicroscopic Chromosomal Deletions in Patients with Idiopathic Congenital Eye Malformations

Purpose

Design

Methods

Results

Conclusions

Methods

Agilent Array Comparative Genomic Hybridization

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