Overview of General Management Principles for Heterophoria Associated with High AC/A Ratio
Optical correction of ametropia still remains the first issue that should be considered. However, as evidenced by
Case 10.2, the consideration of added lenses is close to the top of the list in
Table 10.1. In high AC/A cases, correction of the refractive error may be helpful for two reasons. The first is that the presence of an uncorrected refractive error may create an imbalance between the two eyes, leading to sensory fusion disturbances, or may create decreased fusional ability because of blurred retinal images. The second reason is that, because of the high AC/A, correction of the ametropia may have a beneficial effect on the magnitude of the deviation.
Thus, in cases of convergence excess associated with high tonic vergence, horizontal prism is an important consideration. When convergence excess is associated with a normal or low tonic vergence, prism is generally not necessary.
Although amblyopia is uncommon in nonstrabismic binocular vision anomalies, it can occur if the phoria is associated with a significant degree of anisometropia. Although anisometropic amblyopia is typically shallow (about 20/60 to 20/80), one of the early considerations should be treatment of amblyopia using occlusion and vision therapy. The use of occlusion and specific vision therapy procedures for the treatment of the amblyopia, and any associated suppression, always needs to be considered immediately after prescribing for the anisometropia and considering prism to compensate for a vertical phoria. In cases of convergence excess or divergence excess associated with anisometropia, we recommend part-time occlusion. Several (2 to 4) hours of occlusion using an opaque patch along with active amblyopia therapy is usually sufficient to resolve the amblyopia. Details regarding the evaluation and management of anisometropic amblyopia are provided in
Chapter 17. In almost all cases, however, amblyopia will not be present in either convergence or divergence excess. Thus, after consideration of ametropia, added lenses, and prism, vision therapy is the next treatment issue.
In many cases of convergence excess, the use of added lenses and prism will be sufficient to successfully treat the patient. If NFV is severely reduced, or the magnitude of the esophoria is very large, or if the patient remains uncomfortable even after wearing the glasses, vision therapy should be recommended. In contrast, vision therapy is the primary treatment option for divergence excess. In general, vision therapy is more effective for divergence excess, whereas base-out prism and added plus lenses tend to be more effective for convergence excess.
PROGNOSIS FOR BINOCULAR VISION DISORDERS ASSOCIATED WITH HIGH AC/A RATIOS
The prognosis for successful treatment of convergence excess is excellent. In many cases the use of lenses, added lenses, and prism will be sufficient. If the patient is still symptomatic after these other interventions, vision therapy can be used and will generally lead to success. It would be rare, therefore, to be unable to successfully treat a patient with convergence excess. Failures with these patients are almost always associated with refusal to wear glasses or poor compliance with vision therapy.
The treatment of convergence excess with vision therapy has received some attention in the literature. In a record review of 12 patients with convergence excess who underwent vision therapy, Shorter and Hatch
1 found that
8 (66%) of 12 patients reported improved symptoms, and 5 (62.5%) of the 8 patients with complete data showed increased NFV. The changes were not statistically significant, however. Grisham et al
2 and Wick
3 each reported a case of convergence excess that showed increased NFV and reduced symptoms after vision therapy. Ficcara et al
4 performed a retrospective review of 31 patients (mean age 15.9 years) with convergence excess. The mean number of vision therapy visits was 19.4. There was a significant reduction in symptoms and significant improvement in NFV and PRA. The authors found that the most important factor in determining success was the magnitude of the near phoria prior to vision therapy. Gallaway and Scheiman
5 also performed a retrospective analysis of 83 consecutive patients treated with vision therapy for convergence excess. In contrast to the study by Ficcara et al,
4 which took place at an optometry school clinic, this study consisted of private practice patients. Thus, the testing was standardized within a practice, and two clinicians performed all the measurements. Statistically significant changes were found in direct and indirect measures of NFV, and 84% of patients reported total elimination of symptoms. Vision therapy does appear to be a viable alternative for patients with convergence excess.
In contrast to the success of added lenses with convergence excess, divergence excess responds best to vision therapy. Many studies have evaluated the efficacy of vision therapy for divergence excess. Goldrich
6 reported on the success of vision therapy in a sample of 28 divergence excess patients. He developed criteria for excellent, good, fair, and poor outcomes. To be placed in the excellent category, a patient had to be free from asthenopia, have a phoria at all times, and have normal binocular findings. Placement in the good category meant that the patient was also free from asthenopia and had a phoria at all times, but could have deficiencies on some binocular test findings. A fair result meant that an intermittent strabismus was occasionally observed on cover testing, and a poor result suggested that little improvement had occurred. Twenty patients (71.4%) achieved an excellent rating, and three patients (10.7%) had a good rating. Thus, in 82.1% of the patients, vision therapy was successful in eliminating the intermittent strabismus and asthenopia. For the subjects in the excellent category, the mean number of therapy visits was 20.2 sessions, and for the good category, 28.3 sessions. Only 1 patient was rated poor after treatment.
Pickwell
7 reported on the results of vision therapy on 14 divergence excess patients; 10 patients achieved a satisfactory level, 2 patients showed measurable improvement, and 2 others discontinued therapy before completion. Daum
8 did a retrospective study of 18 divergence excess patients. The duration of treatment was unusually short, only 5.2 weeks, which raises questions about the meaning of his treatment results. However, he did suggest several interesting points relative to prognosis. He found that success was significantly better in subjects who had lower angles of deviation and no vertical deviation.
Other authors who have studied the effectiveness of vision therapy for intermittent exotropia did not differentiate divergence excess from other types of intermittent exotropia. Although this makes the results more difficult to analyze, the results still have relevance for understanding the effectiveness of vision therapy for divergence excess. Divergence excess is the most common type of intermittent exotropia for which surgery is likely to be recommended. As a result, it is reasonable to suggest that many of the patients reported in the following studies had divergence excess strabismus.
In a study of 37 exotropes, Sanfilippo and Clahane
9 found an excellent result in 64.5%, a good result in 9.7%, and a fair result in 22.6%. Only 1 patient (or 3.2%) had a poor result. The authors considered 64.5% to be “cured,” and 32.3% to have immediate improvement in status. They also provided useful data about various factors that influenced the effectiveness of treatment. Amblyopia, a constant deviation, noncomitancy, and a vertical component were negative factors.
Cooper and Leyman
10 reported on a retrospective study of 182 intermittent exotropes treated with orthoptics alone. They found a good result in 58.7% and a fair result in 38.4%. Only 5.6% of their sample failed to make significant progress with orthoptics. Coffey et al
11 reviewed 59 studies of intermittent exotropia treatment and compiled pooled success rates. They calculated the following pooled success rates: 28% for over minus therapy, 28% for prism therapy, 37% for occlusion, 46% for surgery, and 59% for vision therapy. Cooper and Medow
12 also reviewed the literature and concluded that divergence excess in patients younger than 6 years should be treated cautiously so as to reduce or eliminate the possibility of developing amblyopia or permanent loss of stereopsis. They suggested various nonsurgical intervention approaches such as patching, minus lens therapy, and home-based antisuppression treatment initially. Only if the deviation persists or increases should surgical intervention be considered. They suggested that in children older than 6 years, vision therapy is the treatment of choice unless the deviation is large (>35 Δ).
In a recent prospective study by Ma et al,
13 the authors evaluated changes in the Office Control Score after office-based vergence/accommodative therapy for intermittent exotropia in children 12 to 17 years old. They enrolled 14 Chinese participants, ages 6 to 17 years, with intermittent exotropia (excluding the convergence insufficiency type). All participants were treated with 12 weeks of office-based vergence/accommodative therapy. Therapy included vergence, accommodative, antisuppression, and monocular fixation in binocular field techniques. The primary outcome measure was the change in the Office Control Score from the baseline visit to the
13-week outcome visit. In this selected group of children with intermittent exotropia, 12 weeks of office-based vergence/accommodative therapy with home reinforcement resulted in statistically and clinically meaningful improvement in distance control of the exodeviation.
Thus, although the current literature lacks a high-quality randomized clinical trial, it does support the effectiveness of vision therapy in the treatment of divergence excess and, when compared to the cure rates for surgery described later in this chapter, suggests that vision therapy should be the first treatment option. It is important to keep in mind some of the negative prognostic factors suggested by the studies described earlier. Negative factors include a large angle of deviation (>35 Δ), a large vertical component, and a noncomitancy.
SUMMARY OF KEY POINTS IN TREATING PHORIA PATIENTS ASSOCIATED WITH HIGH AC/A
The primary determinant of the management sequence of high AC/A binocular vision problems is the effectiveness of added lenses. Because of the high AC/A ratio, added lenses have a significant effect on the angle of deviation and are, therefore, an important early treatment consideration. When esophoria is present at distance and correction of hyperopia is not sufficient to decrease the phoria to a manageable level, base-out prism is sometimes useful. At times, the use of lenses, added lenses, and prism will not be enough to restore comfort, and vision therapy is necessary.