Fig. 1
(a–c) Techniques for enlarging the capsulorrhexis when converting from phacoemulsification to MSICS. (a) Nick the capsulorrhexis edge to create a new flap, then tear this flap 360 degrees; (b) Create a series of relaxing incisions in the capsular bag; (c) Employ can‐opener technique
Prolapsing Lens with Loose Zonules or Torn Capsule
When zonular compromise or capsular tear is suspected, steps should be taken to facilitate nuclear delivery while minimizing stress on these structures. If nuclear delivery is hindered by a small pupil, then the pupil should be enlarged. This can be accomplished with bimanual pupillary stretching, iris hooks, or relaxing sphincterotomies. If the capsular opening is too small, this too should be enlarged, as described above. The scleral tunnel should also be widened as needed to minimize resistance to nuclear prolapse [29, 32]. In cases of known or suspected posterior capsular tear, cortex removal should be performed with low irrigation, under the cover of viscoelastic, to avoid extension of the tear. In cases of mild to moderate zonular instability, placement of a capsular tension ring (CTR) can be considered, provided that the capsular bag is intact. If zonular dehiscence is more extensive (4 clock hours or more), a scleral-fixated capsular tension segment (CTS) or modified capsular tension ring (MCTR) is indicated [33]. In these cases, attempts should not be made to dial the nucleus out of the bag as this may result in total dislocation of the lens to the posterior pole. Lenses with severe zonular dehiscence are most safely addressed by a vitreoretinal surgeon via a pars plana approach. Where retina support is unavailable, intracapsular extraction with ACIOL or secondary placement of an iris or scleral-fixated IOL is an option.
Alternative nucleus delivery techniques may also employed to reduce stress on weak zonules or a compromised capsule. Venkatesh described a bimanual prolapse technique using a Sinskey hook and a cyclodialysis spatula. The Sinskey hook is placed through the scleral tunnel and used to gently displace the nucleus toward 6 o’clock. Once the superior pole of the nucleus is visualized, the cyclodialysis spatula is positioned beneath the nucleus via the side port incision. Employing the spatula as a fulcrum, the Sinskey hook is used to dial the nucleus out of the capsular bag. This method allows rotational forces to be absorbed by the cyclodialysis spatula, minimizing stress on the capsule and zonules [29]. Variations of this method have been described using different instruments. Fry described a similar technique known as phaco sandwich, utilizing an irrigating vectis for his supporting instrument rather than a cyclodialysis spatula [34].
Anterior Vitrectomy
The prolapse of vitreous into the anterior chamber requires careful management to avoid potentially devastating consequences. Incarceration of vitreous in the anterior chamber can result in vitreoretinal traction and subsequent cystoid macular edema or retinal detachment. Vitreous in the surgical wound can result in wound leak and endophthalmitis. Automated, high-speed vitrectomy is the procedure of choice in these settings. Manual cellulose sponge vitrectomy, once regarded as viable option in the absence of an automated vitrector, has fallen out of favor due to the retinal traction induced each time the sponge is lifted for cutting of the vitreous [35]. In the setting of conversion from phacoemulsification to MSICS, an automated vitrector is usually available and should be used. Dilute Kenalog (10:1) injected into the anterior chamber is useful to highlight vitreous, thereby facilitating its removal. A secondary benefit is the anti-inflammatory effect of Kenalog, which in theory may reduce the risk of postoperative cystoid macular edema [36]. After thorough automated vitrectomy (preferably confirmed with Kenalog staining), cellulose sponges may be used to extract any remaining vitreous from the external wound, since its adhesions to the retina have been cut [37]. Theoretically, this may help reduce the risk of wound leak and endophthalmitis.
IOL Choice
Worldwide, the rigid 3-piece polymethyl methacrylate (PMMA) intraocular lens is the most commonly used IOL for MSICS. The advantages of PMMA include low cost, good biocompatibility, and relatively low incidence of dysphotopsias. The three-piece design allows for safe, stable implantation in either the capsular bag or ciliary sulcus, depending on the surgical scenario. These IOLs range from 5.00 to 6.5 mm in diameter, with the 6.0 mm size being most commonly used. This optic size is usually well-accommodated by the external incision of the scleral tunnel which is typically 6.5 to 7.0 mm in length. Smaller diameter IOLs (5.0–5.5 mm) may produce more dysphotopsias under scotopic conditions, due to exposure of the optic edge when the pupil is more dilated [38].
When performing phacoemulsification, most surgeons use a foldable, single-piece acrylic or silicone IOL to allow for insertion through a small incision. These single-piece IOLs can also be used when converting from phacoemulsification to MSICS, as long as the posterior capsule remains intact and the lens-zonule complex is sufficiently stable. In the case of a torn posterior capsule, however, generally a 3-piece IOL should be placed in the ciliary sulcus. An exception would be in the case of a stable round hole, without vitreous loss. In this case, placement of a single-piece IOL in the capsular bag can be considered. A single-piece IOL should never be placed in the ciliary sulcus as this can lead to iris chafing and subsequent uveitis-glaucoma-hyphema (UGH) syndrome [39]. If zonular instability is detected, placement of a capsular tension ring (CTR) should be considered prior to IOL placement in either the bag or sulcus [33].
When sulcus IOL placement is needed, it is important to adjust the lens power calculation to account for the relatively anterior position of the sulcus compared to the capsular bag. Failure to account for this change in effective lens position will result in myopic surprise. Several studies have shown that the power of the sulcus-based IOL should be between 0.5 D and 1.0 D less than the power calculated for in-the-bag placement [40, 41].
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