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The Problem |
“I see two of things.” |
Common Causes |
Physiological diplopia |
Breakdown of phoria |
Cranial nerve palsy |
Third nerve palsy |
Fourth nerve palsy |
Sixth nerve palsy |
Other Causes |
Decompensated childhood strabismus |
Duane syndrome |
Myasthenia gravis (discussed in ptosis chapter) |
KEY FINDINGS |
History |
Physiological diplopia |
Usually noticed about ages 5 to 6 years |
Most common in bright, observant children |
Not bothered by symptoms |
Breakdown of phoria |
Often no known history of strabismus |
Develop strabismus and diplopia during severe illness |
Resolves after recovery of illness |
Cranial nerve palsies |
Third nerve palsy |
Horizontal and vertical diplopia |
Ptosis |
Unequal pupils (anisocoria) |
Fourth nerve palsy |
Usually gradually worsening vertical diplopia |
Head tilt |
Sixth nerve palsy |
Horizontal diplopia |
Recent viral illness |
Idiopathic intracranial hypertension |
Headache |
Brief episodes of vision loss (transient visual obscurations) |
Recent medication change |
Corticosteroids, isotretinoic acid, others |
Examination |
Physiological diplopia |
Normal ophthalmic examination |
Normal physical examination |
Breakdown of phoria |
Variable esotropia or exotropia |
No limitation of extraocular movements |
Cranial nerve palsies |
Fourth nerve palsy |
Usually head tilt |
Eyes straight when head tilted to unaffected side |
Vertical misalignment when tilted to affected side |
Sixth nerve palsy |
Esotropia |
Inability to move affected eye outward |
Idiopathic intracranial hypertension |
Obesity |
Papilledema |
Third nerve palsy |
Eye out and down |
Ptosis on affected side |
Anisocoria (affected pupil larger in acquired third nerve palsy) |
Possible other neurological signs |
- 1. Physiological diplopia. This is a normal phenomenon that is most commonly noted by bright and observant children around ages 5 to 6 years. The eyes normally focus on objects in a single plane, and these are seen as single images. Objects in front of or behind the object of attention appear to be double, but most people do not notice this. The diplopia can be demonstrated by holding one finger up at arm’s distance in front of your face, with another object (e.g., something on the wall) in the background in line with your finger. If you focus on your finger but pay attention to the object in the background, the background object will appear double. Conversely, if you focus on the background object but pay attention to your finger, the finger will appear double (Figure 11–1). Most of the time these double images are ignored, but children may become aware of them and report them to their parents.
- 2. Breakdown of a phoria. Many normal individuals have a phoria. A phoria is a tendency for the eyes to become misaligned when one eye is covered. The eyes are straight during normal viewing conditions with both eyes open. With a phoria, when one is covered it drifts off center (either inward or outward). The eye returns to its normal position when the eye is uncovered (Figure 11–2). In some patients, usually in association with severe illness or trauma, the ability to control the phoria is temporarily lost, and they develop manifest strabismus (esotropia or exotropia) and diplopia. This usually resolves in conjunction with recovery from the underlying problem.
- 3. Fourth nerve palsy. This is most often congenital and not associated with other neurological problems.
- 4. Third nerve palsy. Acquired third nerve palsy may result from many different neurological problems.
- 5. Sixth nerve palsy. Most common causes are transient sixth nerve palsy of childhood (often associated with preceding viral illness) and increased intracranial pressure.