BASICS
DESCRIPTION
• Small, saucer-like excavation at the corneal margin
• Most often form an ellipse; 2 × 1.5 mm parallel to the limbus
• Associated with adjacent elevation of paralimbal tissue
EPIDEMIOLOGY
Incidence
• 9% after trabeculectomy (1)
• Up to 19% after muscle surgery (2)
RISK FACTORS
Any process causing elevation of the perilimbal tissue
PATHOPHYSIOLOGY
Localized dehydration of the cornea secondary to a localized break in the precorneal oily tear film layer
ETIOLOGY
Elevation of paralimbal tissue leads to a change in the tear film probably by affecting lid function
COMMONLY ASSOCIATED CONDITIONS
• Episcleritis
• Pinguecula
• Pterygium
• Subconjunctival injection
• Glaucoma surgery with creation of a filtering bleb
• Subconjunctival hemorrhage
• Limbal malignancy
• Paralytic lagophthalmus
DIAGNOSIS
HISTORY
• Recent surgery
• Any change in the appearance of the eye
PHYSICAL EXAM
• Apparent corneal thinning evident on slit lamp exam (3)
• Steep wall on the corneal side, sloping wall on the limbal side
• May or may not stain with fluorescein
• Cornea can appear markedly thinned (may resemble a descemetocele without a bulge)
DIFFERENTIAL DIAGNOSIS
• Peripheral ulcerative keratitis
• Corneal ulcer
• Terrien’s marginal degeneration
TREATMENT
MEDICATION
First Line
• Artificial tears, 1 drop q.i.d (3)
• Ointment (antibiotic or tear) q.h.s (3)
Second Line
Topical antibiotic, 1 drop q.i.d (2)
ADDITIONAL TREATMENT
General Measures
• Patching of the involved eye for a day (3)
• Treatment of the cause for the tissue elevation
ONGOING CARE
FOLLOW-UP RECOMMENDATIONS
Should be seen in a week
PROGNOSIS
• If treated, resolves without sequelae
• May leave scar if present for a prolonged period of time
COMPLICATIONS
• Rarely, severe thinning may occur (4)
• May need surgical intervention (4)
REFERENCES
1. Fresina M, Campos EC. Corneal ‘dellen’ as a complication of strabismus surgery. Eye 2009;23(1):161–163.
2. Soong HK, Quigley HA. Dellen associated with filtering blebs. Arch Ophthalmol 1983;101:385–387.
3. Baum JL, Mishima S, Boruchoff SA. On the nature of dellen. Arch Ophthalmol 1968;79:657–662.
4. Insler MS, Tauber S, Packer A. Descemetocele formation in a patient with a postoperative corneal dellen. Cornea 1989;8:129–130.

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