Media Type: Textbook

Synopsis: During recent years, Fundus autofluorescence (FAF) imaging has been shown to be useful in various retinal diseases with regard to diagnosis, identification of disease progression, and monitoring of response to novel therapies. FAF imaging gives additional information above and beyond conventional imaging tools and should be used in evaluation of retinal pathologies.

Target Audience: Ophthalmologists

Review: This book provides comprehensive, up-to-date information on the use of FAF imaging in the evaluation of retinal disease. The 15 chapters in this book are divided to two main sections – basic science and clinical science. The basic science chapters focus on the mechanism of accumulation of lipofuscin, the main fluorophore in the retina generating the FAF signal; different imaging techniques available to image FAF; measures to quantify FAF findings; and interpretation of FAF images.

The clinical science chapters illustrate the distribution pattern of FAF in the healthy macula and in various retinal pathologies such as age-related macular degeneration, inherited retinal dystrophies, posterior uveitis, central serous chorioretinopathy, macular holes, and intraocular tumors. Each chapter gives a brief description of pathophysiology and compares FAF findings with other imaging techniques such as color fundus photographs, fluorescein angiography (FA), and indocyanine-green angiography (ICG), and optical coherence tomography (OCT). Figures and examples presented are of high quality, in terms of both photographic technique and disease description.

In summary, this is an up-to-date, organized, well-written, and well-illustrated book that may be used as a reference by general ophthalmologists as well as retina specialists to understand FAF characteristics of various retinal diseases.