9 Blepharoptosis
ACQUIRED PTOSIS
Preoperative evaluation
The vast majority of cases of acquired ptosis are aponeurogenic. Nonetheless, the causes of acquired ptosis are diverse, and it is helpful in evaluation and treatment to classify acquired ptosis into the following: aponeurogenic, from involutional or other disinsertional changes in the aponeurosis; myogenic, associated with decreased levator muscle function, as seen in myasthenia gravis or congenital progressive external ophthalmoplegia (CPEO); neurogenic, as seen in third-nerve palsy or Horner’s syndrome; and mechanical, associated with eyelid masses or scarring of the eyelid lamellae. Traumatic ptosis may be considered a separate category, although it actually is a subcategory of each of the foregoing categories.
In the patient workup and evaluation, one must begin with a careful history, with attention to duration and progression of ptosis, daily variation in the severity of ptosis, and any history of dry eye complaints. Examination should focus on determining the severity of ptosis, levator function, lid crease height, and coexisting eye problems, such as lower eyelid retraction, overhanging skin on the upper lid, or contralateral upper eyelid retraction, creating a pseudoptosis on the side in question. Clinical features of a patient with acquired aponeurosis disinsertion consist of good levator function, higher than normal eyelid crease, and a ptotic eyelid that assumes a lower position on down gaze. If a history consistent with myasthenia gravis is suspected, tests for fatigability as well as an edrophonium (Tensilon) test should be performed. The examiner should be cognizant of the frequency of bilateral ptosis that is more apparent on one side. Because of the equal innervation to both levator muscles, correcting only one upper lid may result in worsening the appearance of ptosis on the opposite side. This phenomenon follows Hering’s law and is especially frequent in aponeurogenic ptosis.
Indications for surgery
Adult ptosis is typically symptomatic, whether the complaints relate to visual obstruction or a tired, inattentive appearance. A patient may also complain of forehead fatigue caused by constant brow elevation in an effort to help lift a ptotic eyelid. If repair is being performed for functional indications, it is vital to document the severity of ptosis with diagrams, facial photographs, and perimetry, showing the superior visual field constriction produced by the ptosis. It is also helpful to have photographs and notes available for reference at the time of surgery. A ptosis repair may be performed in most patients at any time. After trauma, it is prudent to wait 6 months before ptosis repair, as function may improve during that time. In myasthenia gravis, or any medical or neurologic condition that may remit with therapy, it is wise to delay surgery until the condition is stable and optimally controlled.
Making procedural choices
With few exceptions, acquired ptosis can be treated by an aponeurotic resection or repair. An external aponeurotic approach directly treats the most common cause for acquired ptosis, aponeurotic rarefaction, or disinsertion. Aponeurotic surgery is also the preferred approach in myogenic or neurogenic ptosis with adequate levator function.
The mullerectomy procedure described by Urist and Putterman provides predictable correction of ptosis based on response to a phenylephrine test in the ptotic eyelid. The simplicity of this procedure and ability to perform formulaic surgery predicted by a pharmacologic test make this technique popular.
Frontalis suspension procedures (see section on “Congenital Ptosis”) may be required in severe neurogenic, myogenic, or traumatic ptosis with the loss of levator function. In acquired unilateral ptosis with poor levator function, it is unnecessary to extirpate the contralateral levator and then suspend both lids. It is much easier for an adult without long-standing visual suppression to learn to use brow function to help elevate a ptotic eyelid. When performing sling procedures or aponeurotic surgery on individuals with ptosis associated with weak eyelid closure (CPEO, myasthenia gravis), one must avoid overcorrection and exposure keratopathy.
Surgical procedure
Aponeurotic resection
The eyelid crease is generally marked along the entire eyelid to correspond with the natural skin crease of the opposite upper lid. In selected adult patients with good levator function, the repair can be accomplished through a small central 12 to 15 mm incision. Anesthesia is obtained by subcutaneous infiltration along the preplaced skin marking with 0.5 to 1.5 ml of 2% lidocaine with 1:100,000 dilution of epinephrine. It is important not to inject too deeply into the eyelid, thereby anesthetizing Müller’s muscle, which can influence intraoperative lid height adjustments. Topical tetracaine is instilled onto the cornea.
While retracting the superior edge of the incision with a double-pronged skin hook, gentle pressure is applied on the globe. With retrograde orbital pressure, the preaponeurotic fat pad bulges forward to tent up the orbital septum.
The foregoing maneuvers are important to identify the preaponeurotic fat pad and to avoid making iatrogenic defects in the aponeurosis.
If the aponeurosis has been disinserted, the disinserted edge is grasped with a forceps and sutured to the anterior surface of the tarsal plate. If there has been no obvious disinsertion, the aponeurosis is then detached from the upper border of the tarsal plate. The peripheral vascular arcade in Müller’s muscle helps to identify this structure. If bleeding occurs in this plane, one should pick up the tissue with the bipolar tip before cauterizing, thereby preventing thermal injury to the underlying cornea.