The Perioperative Management of Patients With Obstructive Sleep Apnea





Introduction


The incidence of obstructive sleep apnea (OSA) has increased dramatically in the past two decades due to the increased incidence of obesity. Many continue to quote a 4% incidence of OSA in the adult population based on a 1994 report. A more recent study using data from the Wisconsin Sleep Cohort Study demonstrated an increased prevalence of OSA based on age, sex, and body mass index (BMI). Using data from the National Health and Nutrition Examination Survey, current estimates of moderate to severe OSA (Apnea/Hypopnea Index [AHI] measured as events/hour ≥15) are 3% among women and 10% among men aged 30 to 49 years and 9% among women and 17% among men aged 50 to 70 years. More importantly, 90% of patients with OSA are estimated to remain undiagnosed. Patients who undergo uvulopalatopharyngoplasty (UPPP) with or without tonsillectomy are most likely to have had a sleep study and a known diagnosis of OSA. However, they may or may not have had a full medical workup for comorbidities and may have complications perioperatively related to their OSA and not the surgical procedure.


The long-term effects of sleep-disordered breathing are associated with increased incidence of hypertension, cardiovascular events, diabetes, and premature death. All of these comorbidities need to be considered when evaluating the perioperative management of patients having surgery for OSA. Although many have written about the safety of performing UPPP with or without tonsillectomy as an outpatient, a more reasonable approach is to evaluate patients based on their current health status, not just the surgical procedure being performed. Pediatric and adult patients with OSA, even if asymptomatic, present special challenges that must be noted to decrease the risk of perioperative morbidity and mortality.


The Joint Commission has received 61 sentinel event reports in which the patient was diagnosed with or suspected of having OSA. Patients can experience complications when receiving opioids or concurrent sedatives (e.g. benzodiazepines) because the medications “diminish the protective arousal reflex triggered by hypoxia, increasing the risk of prolonged apnea and respiratory arrest.”


The Joint Commission announced OSA as a National Patient Safety Goal, focusing on preventing postoperative complications and harm. With the knowledge that 25% of the population has OSA and 90% are untreated, The Joint Commission required hospitals to:




  • Screen patients who show signs they may have sleep apnea.



  • Consider OSA when developing the anesthesia plan of care.



  • Develop a protocol to deal with OSA that must be evidence-based best practice.



  • Use the protocol for patients who are diagnosed with OSA and for patients who are not diagnosed but show signs that they may have OSA as well. The screening process should help staff identify the latter patients.



In 2014 the American Society of Anesthesiologists (ASA) Task Force updated practice guidelines for patients with OSA, which affect perioperative management, including recommendations for inpatient, observation, and outpatient procedures. The guidelines were developed to reduce the likelihood of adverse perioperative outcomes in patients with OSA. Task force members included anesthesiologists in private and academic practices, an otolaryngologist, a bariatric surgeon, and methodologists with expertise on development of practice parameters. The strength of evidence was described as supportive, suggestive, or equivocal when sufficient numbers of studies existed. With a lack of scientific evidence in the literature, the terms used were silent, insufficient, or inadequate.





Evaluation of the Patient with OSA


The preoperative evaluation of patients by anesthesia should include medical review of the patient and presence of increased BMI, hypertension, larger neck circumference, and a history of snoring or respiratory pauses. In the absence of a sleep study, a presumptive diagnosis of OSA may be made and perioperative management based on that assessment ( Table 62.1 ). The severity of OSA, the type of surgical procedure, and the need for postoperative analgesics should be considered in determining the perioperative risk from OSA ( Table 62.2 ).



Table 62.1

Identification and Assessment of OSA



























  • A.

    Clinical signs and symptoms suggesting the possibility of OSA



    • 1.

      Predisposing physical characteristics




      • Adult patients: BMI 35 kg/m 2



      • Pediatric patients: 95th percentile for age and sex



      • Neck circumference 17 inches (men) or 16 inches (women)



      • Craniofacial abnormalities affecting the airway



      • Anatomical nasal obstruction



      • Tonsils nearly touching or touching in the midline



    • 2.

      History of apparent airway obstruction during sleep


      Two or more of the following are present: (if patient lives alone or sleep is not observed by another person then only one condition needs to be present)




      • Loud snoring (loud enough to be heard through closed door)



      • Frequent snoring



      • Observed pauses in breathing during sleep



      • Awakens from sleep with choking sensation



      • Frequent arousals from sleep



      • Pediatric patients:




        • Intermittent vocalization during sleep



        • Parental report of restless sleep, difficulty breathing, or struggling respiratory efforts during sleep



        • Child with night terrors



        • Child sleeps in unusual positions



        • Child with new onset enuresis




    • 3.

      Somnolence (one or more of the following is present)




      • Frequent daytime somnolence or fatigure despite adequate “sleep”



      • Falls asleep easily in a nonstimulating environment (e.g. watching television, reading, riding in or driving a car) despite adequate “sleep”



      • Pediatric patients: parent or teacher comments that child appears sleepy during the day, is easily distracted, is overly aggressive, is irritable, or has diffculty concentrating



      • Pediatric patients: child often difficult to arouse at usual awakening time




    If a patient has signs or symptoms in two or more of the above categories, there is a significant probability that he or she has OSA. The severity of OSA may be determined by sleep study (see below). If a sleep study is not available, such patients should be treated as though they have moderate sleep apnea unless one or more of the signs or symptoms above is severely abnormal (e.g. markedly increased BMI or neck circumference, respiratory pauses which are frightening to the observer, patient regularly falls asleep within minutes after being left unstimulated without another explanation) in which case they should be treated as though they have severe sleep apnea.


  • B.

    If a sleep study has been done, the results should be used to determine the perioperative anesthetic management of a patient. However, because sleep laboratories differ in their criteria for detecting episodes of apnea and hypopnea, the Task Force believes that the sleep laboratory’s assessment (none, mild, moderate, or severe) should take precedence over the actual AHI. If the overall severity is not indicated, it may be determined by using the table below:

Severity of OSA Adult AHI Pediatric AHI
None 0–5 0
Mild OSA 6–20 1–5
Moderate OSA 21–40 6–10
Severe OSA >40 >10

AHI, Apnea/Hypopnea Index: the number of episodes of sleep-disordered breathing per hour; BMI, body mass index; OSA, obstructive sleep apnea.

(With permission from Practice Guidelines for the Perioperative Management of Patience with Obstrictive Sleep Apnea. Chapter 60. Pp. 1083-1087. Anesthesia. 2006: 104: 1081-93.)

Jun 10, 2019 | Posted by in OTOLARYNGOLOGY | Comments Off on The Perioperative Management of Patients With Obstructive Sleep Apnea

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