We appreciate Dr Cooke’s comments and interest in the Infant Aphakia Treatment Study (IATS) population for comparison of intraocular lens (IOL) calculation formula performance. We also appreciate his assistance in accessing some of the additional formulae. The table shows absolute prediction errors for the IATS eyes using the manufacturer’s A-constant. Of the 4 additional formulae examined (bold), T2 had the smallest mean and median absolute prediction error.
Table
Absolute Prediction Error by Intraocular Lens Calculation Formula using Manufacturer Constants
| Formula (n=43) | Absolute Predictor Error (Diopters) | |
|---|---|---|
| Mean ± SD a | Median ( a ) | |
| Haigis (n=33) | 3.5 ± 2.2 | 3.5 (1.4, 5.1) |
| Hoffer Q | 2.6 ± 2.0 | 2.1 (0.7, 4.0) |
| Holladay 1 | 1.7 ± 1.3 | 1.2 (0.7, 2.5) |
| Holladay 2 | 1.9 ± 1.5 | 1.4 (0.6, 2.9) |
| Olsen (n=33) | 2.2 ± 1.7 | 1.6 (0.9, 3.3) |
| SRK/T | 1.4 ± 1.1 | 1.3 (0.3, 2.1) |
| SRK II | 2.4 ± 1.8 | 2.2 (0.9, 3.6) |
| T2 | 1.3 ± 1.0 | 1.1 (0.5, 2.0) |
| Universal | 3.0 ± 2.2 | 2.8 (1.1, 4.7) |
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