We appreciate the insightful comments of Dr Park and associates on our published article. We agree with their opinion that the use of measurements from only 1 eye for studies involving eye-specific outcomes is recommended for the statistical analysis because of inter-eye correlation. Otherwise, the model-based analysis such as mixed model is useful when both eyes from 1 patient are included. We examined 60 eyes of 35 consecutive patients undergoing posterior chamber phakic intraocular lens implantation in the current study, in accordance with many published studies on refractive surgery. However, even when we included 35 eyes of 35 patients, we obtained similar results that the explanatory variables relevant to the myopic regression were the preoperative axial length and patient age. Moreover, the normality of all data samples was first checked by the Kolmogorov-Smirnov test. Since the data did not fulfill the criteria for normal distribution, the Spearman correlation coefficient was used to assess the univariate relationship of myopic regression with other variables in the present study. Even when the Pearson correlation coefficient was used for statistical analysis, we obtained almost similar results that there were significant correlations of myopic regression with the preoperative axial length and patient age, and no significant correlation shown with other clinical factors. Accordingly, we believe that eyes of older patients and eyes with greater axial length showed greater long-term myopic shift after posterior chamber phakic intraocular lens implantation.

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Jan 8, 2017 | Posted by in OPHTHALMOLOGY | Comments Off on Reply

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