Abstract
Objective
The objective of the study was to describe our experience with modifications of the Miccoli minimally invasive thyroidectomy.
Design
Planned analysis of a prospectively maintained database was undertaken after Institutional Review Board approval.
Methods
Demographic and surgical data were obtained and analyzed with attention to age, sex, pathology, incision lengths, and complications.
Results
From a single-surgeon series of 785 consecutive thyroidectomies, 178 patients were identified who underwent an endoscopic minimally invasive thyroidectomy. A series of modifications of the classic Miccoli technique evolved over a period of 4 years and include presurgical factors (patient marking in holding area, intubation with laryngeal EMG tube using videolaryngoscope, rotation of operating table away from anesthesia), intraoperative principles (use of operative loupes, slave monitor, laryngeal nerve monitoring, and novel instrumentation; identification of the medial cleft and ligation of superior pedicle bundle using ultrasonic technology; avoidance of clips), and postoperative techniques (deep extubation, laryngeal endoscopy, outpatient management, and oral calcium supplementation).
Conclusions
A minimally invasive endoscopic thyroidectomy is possible even in a practice with moderate surgical volumes by using several techniques that facilitate the performance of this procedure. A high success rate and low complication rate can be achieved, resulting in improved patient satisfaction.
1
Introduction
After nearly a hundred years of performing a thyroidectomy essentially the way it was described by Theodore Kocher in the 19th century, the past decade has seen dramatic changes in modern surgical technique . Much of this change has been technologically driven, with the introduction of high-resolution endoscopy . advanced energy devices , and the evolution of robust laryngeal nerve monitoring . In addition to a faster and probably safer thyroidectomy, the possibility of accomplishing this procedure through a smaller incision has been widely recognized and increasingly embraced .
Several teams of surgeons around the world led the search for a less invasive and more cosmetically appealing approach to a thyroidectomy . Miccoli and his colleagues in Pisa deserve the credit for advancing the most viable approach, which has ultimately been incorporated by a number of high-volume practices . The essential features of this approach include a small cervical incision and a technique that is gasless and relies on conventional retraction, all of which are aided by the magnification afforded with a 5-mm angled laparoscope. The principal advantages are improved visualization, superior cosmetic outcome, and increased patient satisfaction. A downstream benefit that has been derived is the possibility of true outpatient surgery , particularly when combined with laryngeal nerve monitoring .
Because of the unusual nature of the endocrine practice in Pisa (surgical volumes exceeding 3000 cases per year), widespread application of this technique has been somewhat limited and, for practical purposes, has been confined to high-volume surgeons who have plentiful skilled assistants. We have introduced a number of modifications to this technique that serve to facilitate performance of the procedure and thereby potentially broaden its application beyond high-volume centers. These modifications are composed of preoperative, intraoperative, and postoperative interventions. Although these are particularly helpful for endoscopic and minimally invasive surgery, most of them also serve to make conventional thyroid surgery easier and more straightforward.
2
Methods and materials
A planned analysis of a prospectively maintained database was undertaken after Institutional Review Board approval was granted. Demographic and surgical data from a single-surgeon series of consecutive thyroidectomies from 2003 to 2009 were obtained and analyzed with attention to age, sex, pathology, incision lengths, and complications. Specific modifications of the classically reported Miccoli thyroidectomy are described below. Some of these maneuvers were identified in a previous report . The specific techniques can be segregated into preoperative, intraoperative, and postoperative measures.
2.1
Preoperative techniques
- 1.
The location for the cervical incision is determined preoperatively in the holding area with the patient sitting or standing upright. This is particularly important when a cosmetic outcome is desirable , and serves to ensure that the incision is made in an appropriate vertical location (not so low that it is on the anterior chest wall where the risk of hypertrophic scarring is increased, and not so superior that it will be easily visible postoperatively) and to ensure that there is horizontal symmetry. The line of marking is extended beyond the anticipated incision length, in case lengthening of the incision should be needed intraoperatively. Multiple incision length options can be denoted by vertical hash marks ( Fig. 1 ).
- 2.
The use of laryngeal nerve monitoring is a natural complement to the necessarily reduced aperture represented by minimal access thyroid surgery. To simplify this undertaking, the GlideScope (Verathon, Inc., Bothell, WA) device is used to accomplish intubation, so that proper positioning of the electromyographic endotracheal tube can be confirmed. The GlideScope is also profoundly helpful with the difficult airway.
- 3.
Because of the multitude of devices used to accomplish a modern thyroidectomy, rotation of the operating table 180° from the anesthesiologist allows comfortable positioning of surgeon, assistants, and technology ( Fig. 2 ).
2.2
Intraoperative techniques
- 1.
Although no modifications have been made to the excellent visualization that can be obtained with the 30°, 5-mm laparoscope, we have introduced the use of a slave monitor ( Fig. 2 ) to facilitate participation by the camera assistant and also for improved education of the retractor assistant. Taking this a step further, these surgeries are even more easily accomplished in an endoscopic suite; and this has now become our preference.
- 2.
For the nonendoscopic portions of the minimally invasive video-assisted thyroidectomy and for all other thyroid procedures, loupe magnification combined with a portable battery-powered headlight optimizes visualization as well as surgeon comfort.
- 3.
Instrumentation has emerged that in some ways represents an improvement upon the original Miccoli video-assisted thyroidectomy set. The Medtronic (Jacksonville, FL) thyroidectomy instrument set incorporates a nonreflective finish on its retractors, which are angled more than 90° to minimize the interference with the anterior chest wall and the face. The atraumatic suction has a malleable shaft, variable suction strength, and a blunt tip; and therefore, suction trauma to both the parathyroid glands and the laryngeal nerves may be minimized. A specially designed peanut-holder allows use of this type of cottonoid in a small space.
- 4.
When making the horizontal surgical incision, we have found it to be useful to reach deep and beyond the edge of the incision to horizontally divide the platysma to maximize the exposure achieved by a given incision and thereby facilitate delivery of the thyroid through the incision.
- 5.
We have found the management of the superior pole to be easier when the avascular cleft between the inferior constrictor muscles and the superior pole of the thyroid gland is identified and developed ( Fig. 3 ). Furthermore, when combined with lateral dissection of the superior pole, the entire upper pedicle can be ligated using a Harmonic device (Ethicon Endo-Surgery, Cincinnati, OH) ( Fig. 4 ). This thereby minimizes trauma introduced by dissection of the vessels and makes the ligation of the superior pole vasculature easier and faster.
- 6.
We prefer a completely clipless and sutureless removal of the thyroid gland. For example, even in the region of the recurrent nerve, we have not needed to use sutures or clips to achieve hemostasis. Instead, we favor the use of ultrasonic energy, which we have found to be safe and advantageous.
- 7.
In selected patients, a lateral endoscopic approach can be undertaken ( Fig. 5 ). Although this obviates the possibility of performing a bilateral thyroidectomy through the same incision, occasional patient preference may dictate this access. Although a somewhat unfamiliar approach to most surgeons, it is similar to the lateral approach to a superior parathyroidectomy, in which the gland is approached posterior to the strap muscles.
2.3
Postoperative techniques
- 1.
For all thyroid surgeries, including endoscopic minimally invasive techniques, a deep extubation of the patient (which implies removal of the endotracheal tube while the patient is asleep but breathing spontaneously) is very helpful for minimizing coughing and bucking, which may lead to bothersome oozing.
- 2.
We prefer that all patients undergo preoperative laryngoscopy to identify unanticipated preexisting nerve dysfunction . Postoperatively, all patients also undergo laryngeal examination in the postanesthesia care unit to confirm absence of laryngeal dysfunction before discharge. Occasionally, very transient nerve paresis can be appreciated at this examination, which is resolved by the time of the first postoperative visit. Therefore, useful information may be derived.
- 3.
An important departure from the practice of the Miccoli thyroidectomy in Italy is that nearly all of our patients undergoing endoscopic thyroidectomy are managed on an outpatient basis, including those undergoing total thyroidectomy. To introduce a measure of safety with this approach, patients in whom all 4 parathyroid glands are at risk during the surgery are treated prophylactically with oral calcium and vitamin D supplementation .