Common Variable Immunodeficiency with Granulomatous Panuveitis





Cutaneous nodules, granulomatous uveitis and oligoarthritis in child


History of Present Illness


A 5-year-old girl presented with a complaint of red eye and blurred vision left eye (OS) for the past 4 months. She had a history of pneumonia at 4 years of age, which required hospitalization. Shortly afterward she developed a swollen, painful right knee and left interphalangeal joint. For the past 6 months, erythematous, plaquelike, and scaly lesions were observed on her right hand ( Fig. 29.1 ), buttocks, and feet.



Exam












































OD OS
Visual acuity 20/20 20/40
Intraocular pressure (IOP) (mm Hg) 12 10
Sclera/conjunctiva Within normal limits (WNL) No ciliary injection.
Cornea WNL Diffuse mutton fat keratic precipitate (KP) on the inferior half of corneal endothelium
Anterior chamber (AC) WNL 2+ flare, 2+ cell
Iris WNL One Koeppe nodule on the pupillary margin ( Fig. 29.2 )
Lens Clear Clear
Vitreous cavity WNL 2+ vitritis
Retina/optic nerve WNL Mild perivasculitis extending to the periphery



Fig. 29.1


Cutaneous erythematous, plaquelike, and scaly lesions on both hands.

From Artac H, Bozkurt B, Talim B, Reisli I Sarcoid-like granulomas in common variable immunodeficiency. Rheumatol Int. 2009;30:109–112.

Apr 3, 2021 | Posted by in OPHTHALMOLOGY | Comments Off on Common Variable Immunodeficiency with Granulomatous Panuveitis

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