Bilateral Pigment Dispersion





History of Present Illness (HPI)


A 35-year-old healthy woman with no significant past medical or ocular history is referred to the uveitis clinic by an outside ophthalmologist for “bilateral acute anterior uveitis.” She reports that her symptoms started a little over a month ago. Her eyes started to become red and very light sensitive. The referral note mentions that she was started on prednisolone acetate 1% four times a day (QID) both eyes (OU) for “4+ cells” in both anterior chambers and timolol 0.5% twice a day (BID) OU for an intraocular pressure (IOP) of 32 OU upon presentation. Since then, the photophobia and redness have decreased somewhat, she says, but not completely. The referral note goes on to add that despite some symptomatic relief, the cellularity has remained unchanged.



Exam








































OD OS
Visual acuity 20/25 pinhole (PH) 20/20 20/40 PH 20/20
IOP 28 27
Sclera/conjunctiva Trace injection Trace injection
Cornea Clear stroma, pigment on inferior endothelium Clear, pigment on inferior endothelium
Anterior chamber (AC) 4+ pigmented cells, 2+ flare 4+ pigmented cells, 2+ flare
Iris See Figs. 14.1 and 14.2 See Figs. 14.1 and 14.2
Lens Clear Clear
Anterior vitreous 1+ pigmented cells 1+ pigmented cells



Fig. 14.1


(A) Color external photographs of both eyes. The pupils are mid-dilated, and both irises have multiple areas of depigmentation. (B) Slit lamp photograph shows deposition of pigment on the corneal endothelium. (C) Gonioscopy reveals abnormal pigmentation of the angle.

Reproduced from Rueda-Rueda T, Sánchez-Vicente LJ, Moruno-Rodríguez A, Monge-Esquivel J, Muñoz-Morales A, López-Herrero F. Bilateral acute iris depigmentation and bilateral acute iris transillumination syndrome. Arch Spanish Society Opthalmol [English Edition]. 2019;94:355–358.



Fig. 14.2


Color slit lamp photograph of both eyes under retroillumination shows iris transillumination defects (blue arrows).

Reproduced from Rueda-Rueda T, Sánchez-Vicente LJ, Moruno-Rodríguez A, Monge-Esquivel J, Muñoz-Morales A, López-Herrero F. Bilateral acute iris depigmentation and bilateral acute iris transillumination syndrome. Arch Spanish Society Opthalmol [English Edition]. 2019;94:355–358.

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Apr 3, 2021 | Posted by in OPHTHALMOLOGY | Comments Off on Bilateral Pigment Dispersion

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