7.7 Thyroiditis



10.1055/b-0038-162782

7.7 Thyroiditis



Key Features





  • Thyroiditis is an inflammation of the thyroid gland.



  • Hashimoto′s thyroiditis (chronic autoimmune thyroiditis) is the most common type.



  • Other forms include postpartum thyroiditis, subacute thyroiditis (de Quervain), silent thyroiditis, drug-induced thyroiditis, radiation-induced thyroiditis, and acute thyroiditis.


Thyroiditis is a diverse group of disorders associated with inflammation of the thyroid gland. Table 7.7 provides the main types of thyroiditis.





















































Table 7.7 The main types of thyroiditis
 

Hashimoto′s

Painless and postpartum

Subacute (painful)

Suppurative

Cause


Autoimmune

Autoimmune

Viral

Infectious


Clinical features


Painless, firm, bumpy, symmetric goiter (in 10% atrophied thyroid)

Painless, normal-size thyroid or diffuse goiter

Tender, firm goiter

Tender thyroid mass


Thyroid function


Hypothyroidism

Thyrotoxicosis, hypothyroidism, or both

Thyrotoxicosis, hypothyroidism, or both

Euthyroidism


Anti-TPO Abs


High titer, persistent

High titer, persistent

Low titer, absent or transient

Absent


ESR


Normal

Normal

High

High


24-hour RAI uptake


Variable

< 5%

< 5%

Normal



Thyroiditis Associated with Pain and Tenderness



Subacute Thyroiditis


Also known as subacute nonsuppurative thyroiditis, de Quervain thyroiditis, and giant cell or subacute granulomatous thyroiditis, it is a self-limited inflammatory disorder and is the most common cause of thyroid pain.



Etiology

Subacute thyroiditis is most likely caused by a viral infection (coxsackievirus, mumps virus, influenza, echovirus, or adenovirus) or postviral inflammatory process. There is a strong association with HLA-B35.

Only gold members can continue reading. Log In or Register to continue

Related posts:

  1. 7.0 Embryology and Anatomy of the Thyroid Gland
  2. 7.1 Physiology of the Thyroid Gland
  3. 7.6 Thyroid Storm
  4. 7.12 Calcium Disorders

Stay updated, free articles. Join our Telegram channel
Tags: , , , ,
May 19, 2020 | Posted by in OTOLARYNGOLOGY | Comments Off on 7.7 Thyroiditis

Full access? Get Clinical Tree
Get Clinical Tree app for offline access